{"id":38,"date":"2023-09-24T12:53:25","date_gmt":"2023-09-24T10:53:25","guid":{"rendered":"https:\/\/remus.germanywestcentral.cloudapp.azure.com\/publikace-z-dat-registru\/"},"modified":"2026-05-28T12:30:11","modified_gmt":"2026-05-28T10:30:11","slug":"publications-from-registry-data","status":"publish","type":"page","link":"https:\/\/www.multiplesclerosis.cz\/en\/publikace-z-dat-registru\/","title":{"rendered":"Publications from registry data"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"38\" class=\"elementor elementor-38\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-08c3c6b e-flex e-con-boxed e-con e-parent\" data-id=\"08c3c6b\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-93656ca ms-sticky-tabs e-n-tabs-mobile elementor-widget elementor-widget-n-tabs\" data-id=\"93656ca\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"nested-tabs.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"e-n-tabs\" data-widget-number=\"154556106\" aria-label=\"Karty. Polo\u017eky otev\u00edrejte kl\u00e1vesou Enter nebo mezern\u00edk, zav\u00edrejte kl\u00e1vesou Escape a navigujte pomoc\u00ed \u0161ipek.\">\n\t\t\t<div class=\"e-n-tabs-heading\" role=\"tablist\">\n\t\t\t\t\t<button id=\"e-n-tab-title-1545561061\" data-tab-title-id=\"e-n-tab-title-1545561061\" class=\"e-n-tab-title\" aria-selected=\"true\" data-tab-index=\"1\" role=\"tab\" tabindex=\"0\" aria-controls=\"e-n-tab-content-1545561061\" style=\"--n-tabs-title-order: 1;\">\n\t\t\t\t\t\t<span class=\"e-n-tab-title-text\">\n\t\t\t\t\u010cl\u00e1nky\t\t\t<\/span>\n\t\t<\/button>\n\t\t\t\t<button id=\"e-n-tab-title-1545561062\" data-tab-title-id=\"e-n-tab-title-1545561062\" class=\"e-n-tab-title\" aria-selected=\"false\" data-tab-index=\"2\" role=\"tab\" tabindex=\"-1\" aria-controls=\"e-n-tab-content-1545561062\" style=\"--n-tabs-title-order: 2;\">\n\t\t\t\t\t\t<span class=\"e-n-tab-title-text\">\n\t\t\t\tNejnov\u011bj\u0161\u00ed postery\t\t\t<\/span>\n\t\t<\/button>\n\t\t\t\t<button id=\"e-n-tab-title-1545561063\" data-tab-title-id=\"e-n-tab-title-1545561063\" class=\"e-n-tab-title\" aria-selected=\"false\" data-tab-index=\"3\" role=\"tab\" tabindex=\"-1\" aria-controls=\"e-n-tab-content-1545561063\" style=\"--n-tabs-title-order: 3;\">\n\t\t\t\t\t\t<span class=\"e-n-tab-title-text\">\n\t\t\t\tNejnov\u011bj\u0161\u00ed prezentace\t\t\t<\/span>\n\t\t<\/button>\n\t\t\t\t\t<\/div>\n\t\t\t<div class=\"e-n-tabs-content\">\n\t\t\t\t<div id=\"e-n-tab-content-1545561061\" role=\"tabpanel\" aria-labelledby=\"e-n-tab-title-1545561061\" data-tab-index=\"1\" style=\"--n-tabs-title-order: 1;\" class=\"e-active elementor-element elementor-element-bcce395 e-flex e-con-boxed e-con e-child\" data-id=\"bcce395\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-1a65b10 e-con-full e-flex e-con e-child\" data-id=\"1a65b10\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2348a7e elementor-widget elementor-widget-heading\" data-id=\"2348a7e\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Publikace z dat registru ReMuS<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-c712af0 e-con-full e-flex e-con e-child\" data-id=\"c712af0\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-74a0330 elementor-widget__width-inherit elementor-widget elementor-widget-text-editor\" data-id=\"74a0330\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Z registru ReMuS vy\u0161lo od jeho zalo\u017een\u00ed ji\u017e mnoho odborn\u00fdch publikac\u00ed. V\u00fdsledky registru ReMuS jsou d\u00e1le prezentov\u00e1ny na odborn\u00fdch tuzemsk\u00fdch i mezin\u00e1rodn\u00edch konferenc\u00edch a informace z registru tak z\u00edsk\u00e1vaj\u00ed odborn\u00edci na ka\u017edoro\u010dn\u00edm \u010cesk\u00e9m a slovensk\u00e9m neurologick\u00e9m sjezdu, odborn\u00e9m sympoziu Jedli\u010dkovy neuroimunologick\u00e9 a likvorologick\u00e9 dny i na \u0159ad\u011b dal\u0161\u00edch odborn\u00fdch setk\u00e1n\u00edch. V\u00fdsledky ro\u010dn\u00edho sb\u011bru dat jsou tradi\u010dn\u011b zve\u0159ej\u0148ov\u00e1ny p\u0159i p\u0159\u00edle\u017eitosti Sv\u011btov\u00e9ho dne roztrou\u0161en\u00e9 skler\u00f3zy na jarn\u00ed tiskov\u00e9 konferenci v Praze.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d29d75b elementor-widget elementor-widget-image\" data-id=\"d29d75b\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"800\" height=\"534\" src=\"\/wp-content\/uploads\/2024\/08\/publications_mockup2-1024x683.jpg\" class=\"attachment-large size-large wp-image-3237\" alt=\"\" srcset=\"\/wp-content\/uploads\/2024\/08\/publications_mockup2-1024x683.jpg 1024w, \/wp-content\/uploads\/2024\/08\/publications_mockup2-300x200.jpg 300w, \/wp-content\/uploads\/2024\/08\/publications_mockup2-768x512.jpg 768w, \/wp-content\/uploads\/2024\/08\/publications_mockup2.jpg 1200w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-9ef3e02 e-grid e-con-full e-con e-child\" data-id=\"9ef3e02\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-88ae567 e-con-full e-flex e-con e-child\" data-id=\"88ae567\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-95d8d10 custom-blog-post-image elementor-widget elementor-widget-elementskit-blog-posts\" data-id=\"95d8d10\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"elementskit-blog-posts.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"ekit-wid-con\" >\n        <div id=\"post-items--95d8d10\" class=\"row post-items ekit-blog-posts-content masonry \" data-enable=\"no\">\n\n\t\t\t<!-- Blog Carousel markup render -->\n\t\t\t\n\n            <div class=\"col-lg-12 col-md-12\">\n\n                                    <div class=\"elementskit-post-image-card\">\n                        <div class=\"elementskit-entry-header\">\n                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2026\/05\/27\/tiskova-konference-remus-27-kvetna-2026\/\" class=\"elementskit-entry-thumb\">\n                                    <img decoding=\"async\" src=\"\/wp-content\/uploads\/2026\/05\/TK2026_header_image.jpg\" alt=\"Tiskov\u00e1 konference ReMuS | 27. kv\u011btna 2026\">\n                                <\/a><!-- .elementskit-entry-thumb END -->\n                                                            \n                            \n                                                    <\/div><!-- .elementskit-entry-header END -->\n\n                        <div class=\"elementskit-post-body \">\n                            \n                                        \n                                        \t\t\t\t\t\t\t\t\t\t                <h2 class=\"entry-title\">\n                    <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2026\/05\/27\/tiskova-konference-remus-27-kvetna-2026\/\">\n                            Tiskov\u00e1 konference ReMuS | 27. kv\u011btna 2026                    <\/a>\n                <\/h2>\n                                                        \n                                                                                                                                                                            <p>U p\u0159\u00edle\u017eitosti Sv\u011btov\u00e9ho dne roztrou\u0161en\u00e9 skler\u00f3zy (30. kv\u011btna) zve\u0159ej\u0148uje registr ReMuS \u010derstv\u00e1 data, kter\u00e1 potvrzuj\u00ed v\u00fdrazn\u00fd posun v p\u00e9\u010di o pacienty s RS v \u010cesk\u00e9 republice.<\/p>\n                                                                                                                                                                <div class=\"post-meta-list\">\n                                                                                                <span class=\"meta-date\">\n\n                                <i aria-hidden=\"true\" class=\"icon icon-calendar3\"><\/i>\n                                <span class=\"meta-date-text\">\n                                    27. 5. 2026                                <\/span>\n                            <\/span>\n                                                                                                                                                                                                <span class=\"post-cat\">\n\n                                \n\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/category\/akce\/\" rel=\"category tag\">akce<\/a> | <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/category\/publikace\/\" rel=\"category tag\">publikace<\/a>\n                            <\/span>\n                                                                                    <\/div>\n                                                                                                                            <div class=\"btn-wraper\">\n                                    \n                                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2026\/05\/27\/tiskova-konference-remus-27-kvetna-2026\/\" class=\"elementskit-btn  whitespace--normal\" >\n                                                                                    P\u0159e\u010d\u00edst v\u00edce                                         <\/a>\n                                                                    <\/div>\n                                                    <\/div><!-- .elementskit-post-body END -->\n                    <\/div>\n                \n            <\/div>\t\t\t\t\n\n            <div class=\"col-lg-12 col-md-12\">\n\n                                    <div class=\"elementskit-post-image-card\">\n                        <div class=\"elementskit-entry-header\">\n                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2026\/04\/19\/pet-na-pet-ceska-petileta-data-o-kladribinu-na-aan-2026-v-chicagu\/\" class=\"elementskit-entry-thumb\">\n                                    <img decoding=\"async\" src=\"\/wp-content\/uploads\/2026\/04\/AAN2026_Poster_Session_DS_2026-04-19__p03.jpg\" alt=\"P\u011bt na p\u011bt: \u010desk\u00e1 p\u011btilet\u00e1 data o kladribinu na AAN 2026 v Chicagu\">\n                                <\/a><!-- .elementskit-entry-thumb END -->\n                                                            \n                            \n                                                    <\/div><!-- .elementskit-entry-header END -->\n\n                        <div class=\"elementskit-post-body \">\n                            \n                                        \n                                        \t\t\t\t\t\t\t\t\t\t                <h2 class=\"entry-title\">\n                    <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2026\/04\/19\/pet-na-pet-ceska-petileta-data-o-kladribinu-na-aan-2026-v-chicagu\/\">\n                            P\u011bt na p\u011bt: \u010desk\u00e1 p\u011btilet\u00e1 data o kladribinu na AAN 2026 v Chicagu                    <\/a>\n                <\/h2>\n                                                        \n                                                                                                                                                                            <p>Ve dnech 18.\u201322. dubna 2026 prob\u00edh\u00e1 v Chicagu v\u00fdro\u010dn\u00ed kongres Americk\u00e9 neurologick\u00e9 akademie. Za ReMuS tam MUDr. Dominika \u0160\u0165astn\u00e1, Ph.D. prezentovala poster s p\u011btilet\u00fdmi v\u00fdsledky l\u00e9\u010dby kladribinem u \u010desk\u00fdch pacient\u016f s roztrou\u0161enou skler\u00f3zou.<\/p>\n                                                                                                                                                                <div class=\"post-meta-list\">\n                                                                                                <span class=\"meta-date\">\n\n                                <i aria-hidden=\"true\" class=\"icon icon-calendar3\"><\/i>\n                                <span class=\"meta-date-text\">\n                                    19. 4. 2026                                <\/span>\n                            <\/span>\n                                                                                                                                                                                                <span class=\"post-cat\">\n\n                                \n\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/category\/publikace\/\" rel=\"category tag\">publikace<\/a>\n                            <\/span>\n                                                                                    <\/div>\n                                                                                                                            <div class=\"btn-wraper\">\n                                    \n                                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2026\/04\/19\/pet-na-pet-ceska-petileta-data-o-kladribinu-na-aan-2026-v-chicagu\/\" class=\"elementskit-btn  whitespace--normal\" >\n                                                                                    P\u0159e\u010d\u00edst v\u00edce                                         <\/a>\n                                                                    <\/div>\n                                                    <\/div><!-- .elementskit-post-body END -->\n                    <\/div>\n                \n            <\/div>\t\t\t\t\n\n            <div class=\"col-lg-12 col-md-12\">\n\n                                    <div class=\"elementskit-post-image-card\">\n                        <div class=\"elementskit-entry-header\">\n                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2025\/12\/23\/od-slunecniho-zareni-k-boji-proti-roztrousene-skleroze-vliv-hladiny-vitaminu-d-na-aktivitu-roztrousene-sklerozy\/\" class=\"elementskit-entry-thumb\">\n                                    <img decoding=\"async\" src=\"\/wp-content\/uploads\/2025\/12\/vit_D_remus_thumbnail.jpg\" alt=\"Od slune\u010dn\u00edho z\u00e1\u0159en\u00ed k boji proti roztrou\u0161en\u00e9 skler\u00f3ze: vliv hladiny vitam\u00ednu D na aktivitu roztrou\u0161en\u00e9 skler\u00f3zy\">\n                                <\/a><!-- .elementskit-entry-thumb END -->\n                                                            \n                            \n                                                    <\/div><!-- .elementskit-entry-header END -->\n\n                        <div class=\"elementskit-post-body \">\n                            \n                                        \n                                        \t\t\t\t\t\t\t\t\t\t                <h2 class=\"entry-title\">\n                    <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2025\/12\/23\/od-slunecniho-zareni-k-boji-proti-roztrousene-skleroze-vliv-hladiny-vitaminu-d-na-aktivitu-roztrousene-sklerozy\/\">\n                            Od slune\u010dn\u00edho z\u00e1\u0159en\u00ed k boji proti roztrou\u0161en\u00e9 skler\u00f3ze: vliv hladiny vitam\u00ednu D na aktivitu roztrou\u0161en\u00e9 skler\u00f3zy                    <\/a>\n                <\/h2>\n                                                        \n                                                                                                                                                                            <p>Nov\u00e1 studie publikovan\u00e1 v \u010dasopisu Neurological Sciences p\u0159in\u00e1\u0161\u00ed poznatky o vlivu hladin vitaminu D na aktivitu roztrou\u0161en\u00e9 skler\u00f3zy (RS) v re\u00e1ln\u00e9 klinick\u00e9 praxi. Tato pr\u00e1ce, kterou vedla Prim. MUDr. Marta [&hellip;] <\/p>\n                                                                                                                                                                <div class=\"post-meta-list\">\n                                                                                                <span class=\"meta-date\">\n\n                                <i aria-hidden=\"true\" class=\"icon icon-calendar3\"><\/i>\n                                <span class=\"meta-date-text\">\n                                    23. 12. 2025                                <\/span>\n                            <\/span>\n                                                                                                                                                                                                <span class=\"post-cat\">\n\n                                \n\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/category\/publikace\/\" rel=\"category tag\">publikace<\/a>\n                            <\/span>\n                                                                                    <\/div>\n                                                                                                                            <div class=\"btn-wraper\">\n                                    \n                                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2025\/12\/23\/od-slunecniho-zareni-k-boji-proti-roztrousene-skleroze-vliv-hladiny-vitaminu-d-na-aktivitu-roztrousene-sklerozy\/\" class=\"elementskit-btn  whitespace--normal\" >\n                                                                                    P\u0159e\u010d\u00edst v\u00edce                                         <\/a>\n                                                                    <\/div>\n                                                    <\/div><!-- .elementskit-post-body END -->\n                    <\/div>\n                \n            <\/div>\t\t\t\t\n\n            <div class=\"col-lg-12 col-md-12\">\n\n                                    <div class=\"elementskit-post-image-card\">\n                        <div class=\"elementskit-entry-header\">\n                            \n                            \n                                                    <\/div><!-- .elementskit-entry-header END -->\n\n                        <div class=\"elementskit-post-body \">\n                            \n                                        \n                                        \t\t\t\t\t\t\t\t\t\t                <h2 class=\"entry-title\">\n                    <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2025\/04\/08\/remus-v-americe-poster-na-prestiznim-neurologickem-kongresu-american-academy-of-neurology\/\">\n                            ReMuS v Americe \u2013 poster na presti\u017en\u00edm neurologick\u00e9m kongresu American Academy of Neurology                    <\/a>\n                <\/h2>\n                                                        \n                                                                                                                                                                            <p>ReMuS v Americe \u2013 poster na presti\u017en\u00edm neurologick\u00e9m kongresu American Academy of Neurology V dubnu roku 2025 prob\u011bhl kongres AAN, kde Dr. Dominika \u0160\u0165astn\u00e1 prezentovala v\u00fdsledky anal\u00fdzy. \u200e \u200e \u200e [&hellip;] <\/p>\n                                                                                                                                                                <div class=\"post-meta-list\">\n                                                                                                <span class=\"meta-date\">\n\n                                <i aria-hidden=\"true\" class=\"icon icon-calendar3\"><\/i>\n                                <span class=\"meta-date-text\">\n                                    8. 4. 2025                                <\/span>\n                            <\/span>\n                                                                                                                                                                                                <span class=\"post-cat\">\n\n                                \n\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/category\/publikace\/\" rel=\"category tag\">publikace<\/a>\n                            <\/span>\n                                                                                    <\/div>\n                                                                                                                            <div class=\"btn-wraper\">\n                                    \n                                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2025\/04\/08\/remus-v-americe-poster-na-prestiznim-neurologickem-kongresu-american-academy-of-neurology\/\" class=\"elementskit-btn  whitespace--normal\" >\n                                                                                    P\u0159e\u010d\u00edst v\u00edce                                         <\/a>\n                                                                    <\/div>\n                                                    <\/div><!-- .elementskit-post-body END -->\n                    <\/div>\n                \n            <\/div>\t\t\t\t\n\n            <div class=\"col-lg-12 col-md-12\">\n\n                                    <div class=\"elementskit-post-image-card\">\n                        <div class=\"elementskit-entry-header\">\n                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2024\/09\/18\/seznamte-se-s-registrem-remus\/\" class=\"elementskit-entry-thumb\">\n                                    <img decoding=\"async\" src=\"\/wp-content\/uploads\/2024\/09\/ReMuS_ECTRIMS_Brochure_mockup_2B.webp\" alt=\"Seznamte se s registrem ReMuS\">\n                                <\/a><!-- .elementskit-entry-thumb END -->\n                                                            \n                            \n                                                    <\/div><!-- .elementskit-entry-header END -->\n\n                        <div class=\"elementskit-post-body \">\n                            \n                                        \n                                        \t\t\t\t\t\t\t\t\t\t                <h2 class=\"entry-title\">\n                    <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2024\/09\/18\/seznamte-se-s-registrem-remus\/\">\n                            Seznamte se s registrem ReMuS                    <\/a>\n                <\/h2>\n                                                        \n                                                                                                                                                                            <p>Seznamte se s registrem ReMuS Pro prezentaci registru ReMuS na mezin\u00e1rodn\u00edm kongresu o neuroimunologick\u00fdch onemocn\u011bn\u00edch ECTRIMS jsme p\u0159ipravili kr\u00e1tkou prezentaci, kter\u00e1 v\u00e1m poodhal\u00ed, co v\u0161echno se skr\u00fdv\u00e1 pod pokli\u010dkou tohoto [&hellip;] <\/p>\n                                                                                                                                                                <div class=\"post-meta-list\">\n                                                                                                <span class=\"meta-date\">\n\n                                <i aria-hidden=\"true\" class=\"icon icon-calendar3\"><\/i>\n                                <span class=\"meta-date-text\">\n                                    18. 9. 2024                                <\/span>\n                            <\/span>\n                                                                                                                                                                                                <span class=\"post-cat\">\n\n                                \n\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/category\/publikace\/\" rel=\"category tag\">publikace<\/a>\n                            <\/span>\n                                                                                    <\/div>\n                                                                                                                            <div class=\"btn-wraper\">\n                                    \n                                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2024\/09\/18\/seznamte-se-s-registrem-remus\/\" class=\"elementskit-btn  whitespace--normal\" >\n                                                                                    P\u0159e\u010d\u00edst v\u00edce                                         <\/a>\n                                                                    <\/div>\n                                                    <\/div><!-- .elementskit-post-body END -->\n                    <\/div>\n                \n            <\/div>\t\t\t\t\n\n            <div class=\"col-lg-12 col-md-12\">\n\n                                    <div class=\"elementskit-post-image-card\">\n                        <div class=\"elementskit-entry-header\">\n                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2024\/06\/24\/ucinnost-kladribinu-jako-eskalacni-strategie-u-rs-v-realne-klinicke-praxi-poznatky-z-ceskeho-celostatniho-registru-remus\/\" class=\"elementskit-entry-thumb\">\n                                    <img decoding=\"async\" src=\"\/wp-content\/uploads\/2024\/06\/kladribin_article_image.webp\" alt=\"\u00da\u010dinnost kladribinu jako eskala\u010dn\u00ed strategie u RS v re\u00e1ln\u00e9 klinick\u00e9 praxi: Poznatky z \u010desk\u00e9ho celost\u00e1tn\u00edho registru ReMuS\">\n                                <\/a><!-- .elementskit-entry-thumb END -->\n                                                            \n                            \n                                                    <\/div><!-- .elementskit-entry-header END -->\n\n                        <div class=\"elementskit-post-body \">\n                            \n                                        \n                                        \t\t\t\t\t\t\t\t\t\t                <h2 class=\"entry-title\">\n                    <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2024\/06\/24\/ucinnost-kladribinu-jako-eskalacni-strategie-u-rs-v-realne-klinicke-praxi-poznatky-z-ceskeho-celostatniho-registru-remus\/\">\n                            \u00da\u010dinnost kladribinu jako eskala\u010dn\u00ed strategie u RS v re\u00e1ln\u00e9 klinick\u00e9 praxi: Poznatky z \u010desk\u00e9ho celost\u00e1tn\u00edho registru ReMuS                    <\/a>\n                <\/h2>\n                                                        \n                                                                                                                                                                            <p>Nov\u00e1 studie publikovan\u00e1 v \u010dasopisu Journal of Central Nervous System Disease p\u0159in\u00e1\u0161\u00ed poznatky o \u00fa\u010dinnosti kladribinu p\u0159i l\u00e9\u010db\u011b roztrou\u0161en\u00e9 skler\u00f3zy (RS) v re\u00e1ln\u00e9 klinick\u00e9 praxi. Tato pr\u00e1ce vyu\u017e\u00edv\u00e1 data z \u010desk\u00e9ho celon\u00e1rodn\u00edho registru ReMuS a&#8230;<\/p>\n                                                                                                                                                                <div class=\"post-meta-list\">\n                                                                                                <span class=\"meta-date\">\n\n                                <i aria-hidden=\"true\" class=\"icon icon-calendar3\"><\/i>\n                                <span class=\"meta-date-text\">\n                                    24. 6. 2024                                <\/span>\n                            <\/span>\n                                                                                                                                                                                                <span class=\"post-cat\">\n\n                                \n\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/category\/publikace\/\" rel=\"category tag\">publikace<\/a>\n                            <\/span>\n                                                                                    <\/div>\n                                                                                                                            <div class=\"btn-wraper\">\n                                    \n                                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2024\/06\/24\/ucinnost-kladribinu-jako-eskalacni-strategie-u-rs-v-realne-klinicke-praxi-poznatky-z-ceskeho-celostatniho-registru-remus\/\" class=\"elementskit-btn  whitespace--normal\" >\n                                                                                    P\u0159e\u010d\u00edst v\u00edce                                         <\/a>\n                                                                    <\/div>\n                                                    <\/div><!-- .elementskit-post-body END -->\n                    <\/div>\n                \n            <\/div>\t\t\t\t\n\n            <div class=\"col-lg-12 col-md-12\">\n\n                                    <div class=\"elementskit-post-image-card\">\n                        <div class=\"elementskit-entry-header\">\n                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2024\/05\/29\/neurologove-vsichni-pacienti-musi-dostat-kvalitni-peci-tiskova-konference-registru-remus-2024\/\" class=\"elementskit-entry-thumb\">\n                                    <img decoding=\"async\" src=\"\/wp-content\/uploads\/2024\/05\/TK2024_header2.webp\" alt=\"Neurologov\u00e9: v\u0161ichni pacienti mus\u00ed dostat kvalitn\u00ed p\u00e9\u010di | Tiskov\u00e1 konference registru ReMuS 2024\">\n                                <\/a><!-- .elementskit-entry-thumb END -->\n                                                            \n                            \n                                                    <\/div><!-- .elementskit-entry-header END -->\n\n                        <div class=\"elementskit-post-body \">\n                            \n                                        \n                                        \t\t\t\t\t\t\t\t\t\t                <h2 class=\"entry-title\">\n                    <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2024\/05\/29\/neurologove-vsichni-pacienti-musi-dostat-kvalitni-peci-tiskova-konference-registru-remus-2024\/\">\n                            Neurologov\u00e9: v\u0161ichni pacienti mus\u00ed dostat kvalitn\u00ed p\u00e9\u010di | Tiskov\u00e1 konference registru ReMuS 2024                    <\/a>\n                <\/h2>\n                                                        \n                                                                                                                                                                            <p>Pokud \u010dlov\u011bk onemocn\u00ed roztrou\u0161enou skler\u00f3zou (RS), nem\u011blo by z\u00e1le\u017eet na tom, zda \u017eije v Chebu, Kol\u00edn\u011b nebo ve Fr\u00fddku M\u00edstku. Stejnou p\u00e9\u010di by m\u011bl dostat ve v\u0161ech centrech v cel\u00e9 \u010cesk\u00e9 republice. D\u00edky Registru pacient\u016f&#8230;<\/p>\n                                                                                                                                                                <div class=\"post-meta-list\">\n                                                                                                <span class=\"meta-date\">\n\n                                <i aria-hidden=\"true\" class=\"icon icon-calendar3\"><\/i>\n                                <span class=\"meta-date-text\">\n                                    29. 5. 2024                                <\/span>\n                            <\/span>\n                                                                                                                                                                                                <span class=\"post-cat\">\n\n                                \n\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/category\/akce\/\" rel=\"category tag\">akce<\/a> | <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/category\/publikace\/\" rel=\"category tag\">publikace<\/a>\n                            <\/span>\n                                                                                    <\/div>\n                                                                                                                            <div class=\"btn-wraper\">\n                                    \n                                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2024\/05\/29\/neurologove-vsichni-pacienti-musi-dostat-kvalitni-peci-tiskova-konference-registru-remus-2024\/\" class=\"elementskit-btn  whitespace--normal\" >\n                                                                                    P\u0159e\u010d\u00edst v\u00edce                                         <\/a>\n                                                                    <\/div>\n                                                    <\/div><!-- .elementskit-post-body END -->\n                    <\/div>\n                \n            <\/div>\t\t\t\t\n\n            <div class=\"col-lg-12 col-md-12\">\n\n                                    <div class=\"elementskit-post-image-card\">\n                        <div class=\"elementskit-entry-header\">\n                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2024\/04\/01\/big-multiple-sclerosis-data-network-mezinarodni-vyzkumna-sit-registru\/\" class=\"elementskit-entry-thumb\">\n                                    <img decoding=\"async\" src=\"\/wp-content\/uploads\/2024\/04\/2024_BMSD_Glaser_header2.webp\" alt=\"Big Multiple Sclerosis Data network: mezin\u00e1rodn\u00ed v\u00fdzkumn\u00e1 s\u00ed\u0165 registr\u016f\">\n                                <\/a><!-- .elementskit-entry-thumb END -->\n                                                            \n                            \n                                                    <\/div><!-- .elementskit-entry-header END -->\n\n                        <div class=\"elementskit-post-body \">\n                            \n                                        \n                                        \t\t\t\t\t\t\t\t\t\t                <h2 class=\"entry-title\">\n                    <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2024\/04\/01\/big-multiple-sclerosis-data-network-mezinarodni-vyzkumna-sit-registru\/\">\n                            Big Multiple Sclerosis Data network: mezin\u00e1rodn\u00ed v\u00fdzkumn\u00e1 s\u00ed\u0165 registr\u016f                    <\/a>\n                <\/h2>\n                                                        \n                                                                                                                                                                            <p>\u010cl\u00e1nek doc. Anny Glaser ze \u0161v\u00e9dsk\u00e9 univerzity Karolinska Institutet se zam\u011b\u0159uje na v\u00fdznam a p\u0159\u00ednos evropsk\u00fdch registr\u016f roztrou\u0161en\u00e9 skler\u00f3zy, konkr\u00e9tn\u011b projektu Big Multiple Sclerosis Data Network (BMSD), do n\u011bj\u017e je ReMuS aktivn\u011b zapojen&#8230;<\/p>\n                                                                                                                                                                <div class=\"post-meta-list\">\n                                                                                                <span class=\"meta-date\">\n\n                                <i aria-hidden=\"true\" class=\"icon icon-calendar3\"><\/i>\n                                <span class=\"meta-date-text\">\n                                    1. 4. 2024                                <\/span>\n                            <\/span>\n                                                                                                                                                                                                <span class=\"post-cat\">\n\n                                \n\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/category\/publikace\/\" rel=\"category tag\">publikace<\/a>\n                            <\/span>\n                                                                                    <\/div>\n                                                                                                                            <div class=\"btn-wraper\">\n                                    \n                                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2024\/04\/01\/big-multiple-sclerosis-data-network-mezinarodni-vyzkumna-sit-registru\/\" class=\"elementskit-btn  whitespace--normal\" >\n                                                                                    P\u0159e\u010d\u00edst v\u00edce                                         <\/a>\n                                                                    <\/div>\n                                                    <\/div><!-- .elementskit-post-body END -->\n                    <\/div>\n                \n            <\/div>\t\t\t\t\n\n            <div class=\"col-lg-12 col-md-12\">\n\n                                    <div class=\"elementskit-post-image-card\">\n                        <div class=\"elementskit-entry-header\">\n                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2023\/09\/26\/vliv-zdravotnickych-systemu-na-diagnozu-a-pouzivani-lecby-modifikujici-onemocneni-u-roztrousene-sklerozy-pohled-na-pet-evropskych-registru\/\" class=\"elementskit-entry-thumb\">\n                                    <img decoding=\"async\" src=\"\/wp-content\/uploads\/2024\/08\/map-of-europe-with-heart-flag-buttons.webp\" alt=\"Vliv zdravotnick\u00fdch syst\u00e9m\u016f na diagn\u00f3zu a pou\u017e\u00edv\u00e1n\u00ed l\u00e9\u010dby modifikuj\u00edc\u00ed onemocn\u011bn\u00ed u roztrou\u0161en\u00e9 skler\u00f3zy: pohled na p\u011bt evropsk\u00fdch registr\u016f\">\n                                <\/a><!-- .elementskit-entry-thumb END -->\n                                                            \n                            \n                                                    <\/div><!-- .elementskit-entry-header END -->\n\n                        <div class=\"elementskit-post-body \">\n                            \n                                        \n                                        \t\t\t\t\t\t\t\t\t\t                <h2 class=\"entry-title\">\n                    <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2023\/09\/26\/vliv-zdravotnickych-systemu-na-diagnozu-a-pouzivani-lecby-modifikujici-onemocneni-u-roztrousene-sklerozy-pohled-na-pet-evropskych-registru\/\">\n                            Vliv zdravotnick\u00fdch syst\u00e9m\u016f na diagn\u00f3zu a pou\u017e\u00edv\u00e1n\u00ed l\u00e9\u010dby modifikuj\u00edc\u00ed onemocn\u011bn\u00ed u roztrou\u0161en\u00e9 skler\u00f3zy: pohled na p\u011bt evropsk\u00fdch registr\u016f                    <\/a>\n                <\/h2>\n                                                        \n                                                                                                                                                                            <p>T\u00fdm veden\u00fd Richardem Nicholasem se ve sv\u00e9 nov\u00e9 studii zam\u011b\u0159il na to, jak zdravotnick\u00e9 syst\u00e9my v r\u016fzn\u00fdch zem\u00edch ovliv\u0148uj\u00ed klinickou diagn\u00f3zu a p\u0159\u00edstup k l\u00e9\u010db\u011b roztrou\u0161en\u00e9 skler\u00f3zy&#8230;<\/p>\n                                                                                                                                                                <div class=\"post-meta-list\">\n                                                                                                <span class=\"meta-date\">\n\n                                <i aria-hidden=\"true\" class=\"icon icon-calendar3\"><\/i>\n                                <span class=\"meta-date-text\">\n                                    26. 9. 2023                                <\/span>\n                            <\/span>\n                                                                                                                                                                                                <span class=\"post-cat\">\n\n                                \n\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/category\/publikace\/\" rel=\"category tag\">publikace<\/a>\n                            <\/span>\n                                                                                    <\/div>\n                                                                                                                            <div class=\"btn-wraper\">\n                                    \n                                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2023\/09\/26\/vliv-zdravotnickych-systemu-na-diagnozu-a-pouzivani-lecby-modifikujici-onemocneni-u-roztrousene-sklerozy-pohled-na-pet-evropskych-registru\/\" class=\"elementskit-btn  whitespace--normal\" >\n                                                                                    P\u0159e\u010d\u00edst v\u00edce                                         <\/a>\n                                                                    <\/div>\n                                                    <\/div><!-- .elementskit-post-body END -->\n                    <\/div>\n                \n            <\/div>\t\t\t\t\n\n            <div class=\"col-lg-12 col-md-12\">\n\n                                    <div class=\"elementskit-post-image-card\">\n                        <div class=\"elementskit-entry-header\">\n                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2023\/06\/15\/je-kojeni-pri-rs-skodlive-nebo-ne-odpoved-na-zaklade-realnych-dat-z-ceska\/\" class=\"elementskit-entry-thumb\">\n                                    <img decoding=\"async\" src=\"\/wp-content\/uploads\/2024\/08\/breastfeeding_grayscale.webp\" alt=\"Je kojen\u00ed p\u0159i RS \u0161kodliv\u00e9, nebo ne? Odpov\u011b\u010f na z\u00e1klad\u011b re\u00e1ln\u00fdch dat z \u010ceska\">\n                                <\/a><!-- .elementskit-entry-thumb END -->\n                                                            \n                            \n                                                    <\/div><!-- .elementskit-entry-header END -->\n\n                        <div class=\"elementskit-post-body \">\n                            \n                                        \n                                        \t\t\t\t\t\t\t\t\t\t                <h2 class=\"entry-title\">\n                    <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2023\/06\/15\/je-kojeni-pri-rs-skodlive-nebo-ne-odpoved-na-zaklade-realnych-dat-z-ceska\/\">\n                            Je kojen\u00ed p\u0159i RS \u0161kodliv\u00e9, nebo ne? Odpov\u011b\u010f na z\u00e1klad\u011b re\u00e1ln\u00fdch dat z \u010ceska                    <\/a>\n                <\/h2>\n                                                        \n                                                                                                                                                                            <p>Origin\u00e1ln\u00ed \u010dl\u00e1nek MUDr. Pavla Hrad\u00edlka, Ph.D. z Fakultn\u00ed nemocnice Ostrava vych\u00e1zej\u00edc\u00ed z dat registru ReMuS byl uve\u0159ejn\u011bn v odborn\u00e9m \u010dasopise Multiple Sclerosis and Related Disorders. Proto\u017ee vliv kojen\u00ed a jeho d\u00e9lky na pr\u016fb\u011bh roztrou\u0161en\u00e9 skler\u00f3zy je nejasn\u00fd, analyzovali auto\u0159i re\u00e1ln\u00e1 data o koj\u00edc\u00edch \u017een\u00e1ch s RS a pr\u016fb\u011bhu jejich onemocn\u011bn\u00ed&#8230;<\/p>\n                                                                                                                                                                <div class=\"post-meta-list\">\n                                                                                                <span class=\"meta-date\">\n\n                                <i aria-hidden=\"true\" class=\"icon icon-calendar3\"><\/i>\n                                <span class=\"meta-date-text\">\n                                    15. 6. 2023                                <\/span>\n                            <\/span>\n                                                                                                                                                                                                <span class=\"post-cat\">\n\n                                \n\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/category\/publikace\/\" rel=\"category tag\">publikace<\/a>\n                            <\/span>\n                                                                                    <\/div>\n                                                                                                                            <div class=\"btn-wraper\">\n                                    \n                                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2023\/06\/15\/je-kojeni-pri-rs-skodlive-nebo-ne-odpoved-na-zaklade-realnych-dat-z-ceska\/\" class=\"elementskit-btn  whitespace--normal\" >\n                                                                                    P\u0159e\u010d\u00edst v\u00edce                                         <\/a>\n                                                                    <\/div>\n                                                    <\/div><!-- .elementskit-post-body END -->\n                    <\/div>\n                \n            <\/div>\t\t\t\t\n\n            <div class=\"col-lg-12 col-md-12\">\n\n                                    <div class=\"elementskit-post-image-card\">\n                        <div class=\"elementskit-entry-header\">\n                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2023\/06\/12\/prekonava-pocatecni-vysoce-ucinna-lecba-u-roztrousene-sklerozy-strategii-postupne-eskalace-lecby-srovnani-pacientu-s-relabujici-remitentni-roztrousenou-sklerozou-v-ceskem-a-svedskem-narodnim-registru\/\" class=\"elementskit-entry-thumb\">\n                                    <img decoding=\"async\" src=\"\/wp-content\/uploads\/2023\/06\/swedish_flag.webp\" alt=\"P\u0159ekon\u00e1v\u00e1 po\u010d\u00e1te\u010dn\u00ed vysoce \u00fa\u010dinn\u00e1 l\u00e9\u010dba u roztrou\u0161en\u00e9 skler\u00f3zy strategii postupn\u00e9 eskalace l\u00e9\u010dby? Srovn\u00e1n\u00ed pacient\u016f s relabuj\u00edc\u00ed-remitentn\u00ed roztrou\u0161enou skler\u00f3zou v \u010desk\u00e9m a \u0161v\u00e9dsk\u00e9m n\u00e1rodn\u00edm registru roztrou\u0161en\u00e9 skler\u00f3zy.\">\n                                <\/a><!-- .elementskit-entry-thumb END -->\n                                                            \n                            \n                                                    <\/div><!-- .elementskit-entry-header END -->\n\n                        <div class=\"elementskit-post-body \">\n                            \n                                        \n                                        \t\t\t\t\t\t\t\t\t\t                <h2 class=\"entry-title\">\n                    <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2023\/06\/12\/prekonava-pocatecni-vysoce-ucinna-lecba-u-roztrousene-sklerozy-strategii-postupne-eskalace-lecby-srovnani-pacientu-s-relabujici-remitentni-roztrousenou-sklerozou-v-ceskem-a-svedskem-narodnim-registru\/\">\n                            P\u0159ekon\u00e1v\u00e1 po\u010d\u00e1te\u010dn\u00ed vysoce \u00fa\u010dinn\u00e1 l\u00e9\u010dba u roztrou\u0161en\u00e9 skler\u00f3zy strategii postupn\u00e9 eskalace l\u00e9\u010dby? Srovn\u00e1n\u00ed pacient\u016f s relabuj\u00edc\u00ed-remitentn\u00ed roztrou\u0161enou skler\u00f3zou v \u010desk\u00e9m a \u0161v\u00e9dsk\u00e9m n\u00e1rodn\u00edm registru roztrou\u0161en\u00e9 skler\u00f3zy.                    <\/a>\n                <\/h2>\n                                                        \n                                                                                                                                                                            <p>Odborn\u00fd \u010dl\u00e1nek Ing. Terezy Hrn\u010diarov\u00e9, Ph.D. z 1. l\u00e9ka\u0159sk\u00e9 fakulty Univerzity Karlovy se zab\u00fdv\u00e1 problematikou l\u00e9\u010debn\u00fdch strategi\u00ed u relaps-remitentn\u00ed roztrou\u0161en\u00e9 skler\u00f3zy. Ve sv\u00e9 pr\u00e1ci vych\u00e1z\u00ed z dat \u010desk\u00e9ho registru ReMuS a \u0161v\u00e9dsk\u00e9ho SMSR (Swedish MS Registry). Navazuje tak na&#8230;<\/p>\n                                                                                                                                                                <div class=\"post-meta-list\">\n                                                                                                <span class=\"meta-date\">\n\n                                <i aria-hidden=\"true\" class=\"icon icon-calendar3\"><\/i>\n                                <span class=\"meta-date-text\">\n                                    12. 6. 2023                                <\/span>\n                            <\/span>\n                                                                                                                                                                                                <span class=\"post-cat\">\n\n                                \n\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/category\/publikace\/\" rel=\"category tag\">publikace<\/a>\n                            <\/span>\n                                                                                    <\/div>\n                                                                                                                            <div class=\"btn-wraper\">\n                                    \n                                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2023\/06\/12\/prekonava-pocatecni-vysoce-ucinna-lecba-u-roztrousene-sklerozy-strategii-postupne-eskalace-lecby-srovnani-pacientu-s-relabujici-remitentni-roztrousenou-sklerozou-v-ceskem-a-svedskem-narodnim-registru\/\" class=\"elementskit-btn  whitespace--normal\" >\n                                                                                    P\u0159e\u010d\u00edst v\u00edce                                         <\/a>\n                                                                    <\/div>\n                                                    <\/div><!-- .elementskit-post-body END -->\n                    <\/div>\n                \n            <\/div>\t\t\t\t\n\n            <div class=\"col-lg-12 col-md-12\">\n\n                                    <div class=\"elementskit-post-image-card\">\n                        <div class=\"elementskit-entry-header\">\n                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2023\/05\/25\/tiskova-konference-registru-remus-2023\/\" class=\"elementskit-entry-thumb\">\n                                    <img decoding=\"async\" src=\"\/wp-content\/uploads\/2023\/05\/TK2023_header.webp\" alt=\"L\u00e9\u010dba roztrou\u0161en\u00e9 skler\u00f3zy za\u017e\u00edv\u00e1 revoluci | Tiskov\u00e1 konference registru ReMuS 2023\">\n                                <\/a><!-- .elementskit-entry-thumb END -->\n                                                            \n                            \n                                                    <\/div><!-- .elementskit-entry-header END -->\n\n                        <div class=\"elementskit-post-body \">\n                            \n                                        \n                                        \t\t\t\t\t\t\t\t\t\t                <h2 class=\"entry-title\">\n                    <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2023\/05\/25\/tiskova-konference-registru-remus-2023\/\">\n                            L\u00e9\u010dba roztrou\u0161en\u00e9 skler\u00f3zy za\u017e\u00edv\u00e1 revoluci | Tiskov\u00e1 konference registru ReMuS 2023                    <\/a>\n                <\/h2>\n                                                        \n                                                                                                                                                                            <p>K bl\u00ed\u017e\u00edc\u00edmu se sv\u011btov\u00e9mu dni roztrou\u0161en\u00e9 skler\u00f3zy (RS) po\u0159\u00e1dal registr pacient\u016f ReMuS tradi\u010dn\u00ed tiskovou konferenci 25. kv\u011btna 2023. V r\u00e1mci konference byla prezentov\u00e1na nejaktu\u00e1ln\u011bj\u0161\u00ed data o RS a praktick\u00e9 po\u010diny, kter\u00e9 se v r\u00e1mci registru ReMuS poda\u0159ilo b\u011bhem 10 let jeho existence realizovat&#8230;<\/p>\n                                                                                                                                                                <div class=\"post-meta-list\">\n                                                                                                <span class=\"meta-date\">\n\n                                <i aria-hidden=\"true\" class=\"icon icon-calendar3\"><\/i>\n                                <span class=\"meta-date-text\">\n                                    25. 5. 2023                                <\/span>\n                            <\/span>\n                                                                                                                                                                                                <span class=\"post-cat\">\n\n                                \n\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/category\/akce\/\" rel=\"category tag\">akce<\/a> | <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/category\/publikace\/\" rel=\"category tag\">publikace<\/a>\n                            <\/span>\n                                                                                    <\/div>\n                                                                                                                            <div class=\"btn-wraper\">\n                                    \n                                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2023\/05\/25\/tiskova-konference-registru-remus-2023\/\" class=\"elementskit-btn  whitespace--normal\" >\n                                                                                    P\u0159e\u010d\u00edst v\u00edce                                         <\/a>\n                                                                    <\/div>\n                                                    <\/div><!-- .elementskit-post-body END -->\n                    <\/div>\n                \n            <\/div>\t\t\t\t\n\n            <div class=\"col-lg-12 col-md-12\">\n\n                                    <div class=\"elementskit-post-image-card\">\n                        <div class=\"elementskit-entry-header\">\n                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2023\/03\/28\/cesky-narodni-registr-roztrousene-sklerozy-remus-trendy-dat-u-pacientu-s-roztrousenou-sklerozou-u-nichz-byla-v-letech-2013-2021-zahajena-prvni-chorobu-modifikujici-lecba\/\" class=\"elementskit-entry-thumb\">\n                                    <img decoding=\"async\" src=\"\/wp-content\/uploads\/2023\/03\/CZ_image_photo.webp\" alt=\"\u010cesk\u00fd n\u00e1rodn\u00ed registr roztrou\u0161en\u00e9 skler\u00f3zy ReMuS: Trendy dat u pacient\u016f s roztrou\u0161enou skler\u00f3zou, u nich\u017e byla v letech 2013-2021 zah\u00e1jena prvn\u00ed chorobu modifikuj\u00edc\u00ed l\u00e9\u010dba.\">\n                                <\/a><!-- .elementskit-entry-thumb END -->\n                                                            \n                            \n                                                    <\/div><!-- .elementskit-entry-header END -->\n\n                        <div class=\"elementskit-post-body \">\n                            \n                                        \n                                        \t\t\t\t\t\t\t\t\t\t                <h2 class=\"entry-title\">\n                    <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2023\/03\/28\/cesky-narodni-registr-roztrousene-sklerozy-remus-trendy-dat-u-pacientu-s-roztrousenou-sklerozou-u-nichz-byla-v-letech-2013-2021-zahajena-prvni-chorobu-modifikujici-lecba\/\">\n                            \u010cesk\u00fd n\u00e1rodn\u00ed registr roztrou\u0161en\u00e9 skler\u00f3zy ReMuS: Trendy dat u pacient\u016f s roztrou\u0161enou skler\u00f3zou, u nich\u017e byla v letech 2013-2021 zah\u00e1jena prvn\u00ed chorobu modifikuj\u00edc\u00ed l\u00e9\u010dba.                    <\/a>\n                <\/h2>\n                                                        \n                                                                                                                                                                            <p>Roztrou\u0161en\u00e1 skler\u00f3za je v\u00e1\u017en\u00e9 neuroimunologick\u00e9 onemocn\u011bn\u00ed a data o jeho v\u00fdskytu a l\u00e9\u010db\u011b systematicky a dlouhodob\u011b vyhodnocuje n\u00e1rodn\u00ed registr ReMuS. Trendy v l\u00e9\u010db\u011b pacient\u016f v \u010cesk\u00e9 republice se zab\u00fdvala MUDr. Dominika \u0160\u0165astn\u00e1, Ph.D. ze V\u0161eobecn\u00e9 fakultn\u00ed nemocnice v Praze ve sv\u00e9m&#8230;<\/p>\n                                                                                                                                                                <div class=\"post-meta-list\">\n                                                                                                <span class=\"meta-date\">\n\n                                <i aria-hidden=\"true\" class=\"icon icon-calendar3\"><\/i>\n                                <span class=\"meta-date-text\">\n                                    28. 3. 2023                                <\/span>\n                            <\/span>\n                                                                                                                                                                                                <span class=\"post-cat\">\n\n                                \n\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/category\/publikace\/\" rel=\"category tag\">publikace<\/a>\n                            <\/span>\n                                                                                    <\/div>\n                                                                                                                            <div class=\"btn-wraper\">\n                                    \n                                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2023\/03\/28\/cesky-narodni-registr-roztrousene-sklerozy-remus-trendy-dat-u-pacientu-s-roztrousenou-sklerozou-u-nichz-byla-v-letech-2013-2021-zahajena-prvni-chorobu-modifikujici-lecba\/\" class=\"elementskit-btn  whitespace--normal\" >\n                                                                                    P\u0159e\u010d\u00edst v\u00edce                                         <\/a>\n                                                                    <\/div>\n                                                    <\/div><!-- .elementskit-post-body END -->\n                    <\/div>\n                \n            <\/div>\t\t\t\t\n\n            <div class=\"col-lg-12 col-md-12\">\n\n                                    <div class=\"elementskit-post-image-card\">\n                        <div class=\"elementskit-entry-header\">\n                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2023\/02\/16\/podil-a-charakteristiky-sekundarni-progresivni-roztrousene-sklerozy-v-peti-evropskych-registrech-s-vyuzitim-objektivnich-klasifikatoru\/\" class=\"elementskit-entry-thumb\">\n                                    <img decoding=\"async\" src=\"\/wp-content\/uploads\/2023\/02\/europe_abstract_map.webp\" alt=\"Pod\u00edl a charakteristiky sekund\u00e1rn\u00ed progresivn\u00ed roztrou\u0161en\u00e9 skler\u00f3zy v p\u011bti evropsk\u00fdch registrech s vyu\u017eit\u00edm objektivn\u00edch klasifik\u00e1tor\u016f\">\n                                <\/a><!-- .elementskit-entry-thumb END -->\n                                                            \n                            \n                                                    <\/div><!-- .elementskit-entry-header END -->\n\n                        <div class=\"elementskit-post-body \">\n                            \n                                        \n                                        \t\t\t\t\t\t\t\t\t\t                <h2 class=\"entry-title\">\n                    <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2023\/02\/16\/podil-a-charakteristiky-sekundarni-progresivni-roztrousene-sklerozy-v-peti-evropskych-registrech-s-vyuzitim-objektivnich-klasifikatoru\/\">\n                            Pod\u00edl a charakteristiky sekund\u00e1rn\u00ed progresivn\u00ed roztrou\u0161en\u00e9 skler\u00f3zy v p\u011bti evropsk\u00fdch registrech s vyu\u017eit\u00edm objektivn\u00edch klasifik\u00e1tor\u016f                    <\/a>\n                <\/h2>\n                                                        \n                                                                                                                                                                            <p>Sekund\u00e1rn\u011b progresivn\u00ed roztrou\u0161en\u00e1 skler\u00f3za (SPRS) p\u0159edstavuje v\u00fdznamnou f\u00e1zi v\u00fdvoje roztrou\u0161en\u00e9 skler\u00f3zy, kterou je v\u0161ak \u010dasto obt\u00ed\u017en\u00e9 p\u0159esn\u011b diagnostikovat. Studie, proveden\u00e1 v p\u011bti evropsk\u00fdch zem\u00edch, vyu\u017eila objektivn\u00edch klasifik\u00e1tor\u016f ke zji\u0161t\u011bn\u00ed pod\u00edlu a charakteristik SPRS v jednotliv\u00fdch registrech pacient\u016f s roztrou\u0161enou skler\u00f3zou, v\u010detn\u011b n\u00e1rodn\u00edho registru ReMuS. Zji\u0161t\u011bn\u00ed nazna\u010duj\u00ed&#8230;<\/p>\n                                                                                                                                                                <div class=\"post-meta-list\">\n                                                                                                <span class=\"meta-date\">\n\n                                <i aria-hidden=\"true\" class=\"icon icon-calendar3\"><\/i>\n                                <span class=\"meta-date-text\">\n                                    16. 2. 2023                                <\/span>\n                            <\/span>\n                                                                                                                                                                                                <span class=\"post-cat\">\n\n                                \n\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/category\/publikace\/\" rel=\"category tag\">publikace<\/a>\n                            <\/span>\n                                                                                    <\/div>\n                                                                                                                            <div class=\"btn-wraper\">\n                                    \n                                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2023\/02\/16\/podil-a-charakteristiky-sekundarni-progresivni-roztrousene-sklerozy-v-peti-evropskych-registrech-s-vyuzitim-objektivnich-klasifikatoru\/\" class=\"elementskit-btn  whitespace--normal\" >\n                                                                                    P\u0159e\u010d\u00edst v\u00edce                                         <\/a>\n                                                                    <\/div>\n                                                    <\/div><!-- .elementskit-post-body END -->\n                    <\/div>\n                \n            <\/div>\t\t\t\t\n\n            <div class=\"col-lg-12 col-md-12\">\n\n                                    <div class=\"elementskit-post-image-card\">\n                        <div class=\"elementskit-entry-header\">\n                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2022\/07\/02\/byt-ci-nebyt-ockovan-riziko-relapsu-rs-nebo-nmosd-po-ockovani-a-infekci-covid-19\/\" class=\"elementskit-entry-thumb\">\n                                    <img decoding=\"async\" src=\"\/wp-content\/uploads\/2022\/07\/covid19_vaccination.webp\" alt=\"B\u00fdt \u010di neb\u00fdt o\u010dkov\u00e1n: Riziko relapsu RS nebo NMOSD po o\u010dkov\u00e1n\u00ed a infekci COVID-19\">\n                                <\/a><!-- .elementskit-entry-thumb END -->\n                                                            \n                            \n                                                    <\/div><!-- .elementskit-entry-header END -->\n\n                        <div class=\"elementskit-post-body \">\n                            \n                                        \n                                        \t\t\t\t\t\t\t\t\t\t                <h2 class=\"entry-title\">\n                    <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2022\/07\/02\/byt-ci-nebyt-ockovan-riziko-relapsu-rs-nebo-nmosd-po-ockovani-a-infekci-covid-19\/\">\n                            B\u00fdt \u010di neb\u00fdt o\u010dkov\u00e1n: Riziko relapsu RS nebo NMOSD po o\u010dkov\u00e1n\u00ed a infekci COVID-19                    <\/a>\n                <\/h2>\n                                                        \n                                                                                                                                                                            <p>V ned\u00e1vn\u00e9 studii publikovan\u00e9 v \u010dasopise Multiple Sclerosis and Related Disorders zkoumali v\u011bdci riziko relapsu u pacient\u016f s roztrou\u0161enou skler\u00f3zou (RS) a neuromyelitis optica (NMOSD) po o\u010dkov\u00e1n\u00ed proti COVID-19 a po prod\u011bl\u00e1n\u00ed COVID-19. Studie sledovala data z \u010desk\u00e9ho n\u00e1rodn\u00edho registru ReMuS a uk\u00e1zala&#8230;<\/p>\n                                                                                                                                                                <div class=\"post-meta-list\">\n                                                                                                <span class=\"meta-date\">\n\n                                <i aria-hidden=\"true\" class=\"icon icon-calendar3\"><\/i>\n                                <span class=\"meta-date-text\">\n                                    2. 7. 2022                                <\/span>\n                            <\/span>\n                                                                                                                                                                                                <span class=\"post-cat\">\n\n                                \n\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/category\/publikace\/\" rel=\"category tag\">publikace<\/a>\n                            <\/span>\n                                                                                    <\/div>\n                                                                                                                            <div class=\"btn-wraper\">\n                                    \n                                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2022\/07\/02\/byt-ci-nebyt-ockovan-riziko-relapsu-rs-nebo-nmosd-po-ockovani-a-infekci-covid-19\/\" class=\"elementskit-btn  whitespace--normal\" >\n                                                                                    P\u0159e\u010d\u00edst v\u00edce                                         <\/a>\n                                                                    <\/div>\n                                                    <\/div><!-- .elementskit-post-body END -->\n                    <\/div>\n                \n            <\/div>\t\t\t\t\n\n            <div class=\"col-lg-12 col-md-12\">\n\n                                    <div class=\"elementskit-post-image-card\">\n                        <div class=\"elementskit-entry-header\">\n                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2022\/04\/18\/analyza-skupiny-detskych-pacientu-s-relabujici-roztrousenou-sklerozou-udaje-z-ceskeho-narodniho-registru\/\" class=\"elementskit-entry-thumb\">\n                                    <img decoding=\"async\" src=\"\/wp-content\/uploads\/2022\/04\/pediatric_MS_abstract_image.jpg\" alt=\"Anal\u00fdza skupiny d\u011btsk\u00fdch pacient\u016f s relabuj\u00edc\u00ed roztrou\u0161enou skler\u00f3zou: \u00dadaje z \u010desk\u00e9ho n\u00e1rodn\u00edho registru\">\n                                <\/a><!-- .elementskit-entry-thumb END -->\n                                                            \n                            \n                                                    <\/div><!-- .elementskit-entry-header END -->\n\n                        <div class=\"elementskit-post-body \">\n                            \n                                        \n                                        \t\t\t\t\t\t\t\t\t\t                <h2 class=\"entry-title\">\n                    <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2022\/04\/18\/analyza-skupiny-detskych-pacientu-s-relabujici-roztrousenou-sklerozou-udaje-z-ceskeho-narodniho-registru\/\">\n                            Anal\u00fdza skupiny d\u011btsk\u00fdch pacient\u016f s relabuj\u00edc\u00ed roztrou\u0161enou skler\u00f3zou: \u00dadaje z \u010desk\u00e9ho n\u00e1rodn\u00edho registru                    <\/a>\n                <\/h2>\n                                                        \n                                                                                                                                                                            <p>Roztrou\u0161en\u00e1 skler\u00f3za m\u016f\u017ee postihnout i d\u011bti, a\u010dkoli se jedn\u00e1 o vz\u00e1cn\u011bj\u0161\u00ed formu tohoto onemocn\u011bn\u00ed. P\u0159ibli\u017en\u011b 3-10 % pacient\u016f rozvine roztrou\u0161enou skler\u00f3zu p\u0159ed dosa\u017een\u00edm v\u011bku 16 let. Tato studie se zam\u011b\u0159uje na anal\u00fdzu skupiny d\u011btsk\u00fdch pacient\u016f s relabuj\u00edc\u00ed formou roztrou\u0161en\u00e9 skler\u00f3zy, kte\u0159\u00ed zah\u00e1jili l\u00e9\u010dbu&#8230;<\/p>\n                                                                                                                                                                <div class=\"post-meta-list\">\n                                                                                                <span class=\"meta-date\">\n\n                                <i aria-hidden=\"true\" class=\"icon icon-calendar3\"><\/i>\n                                <span class=\"meta-date-text\">\n                                    18. 4. 2022                                <\/span>\n                            <\/span>\n                                                                                                                                                                                                <span class=\"post-cat\">\n\n                                \n\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/category\/publikace\/\" rel=\"category tag\">publikace<\/a>\n                            <\/span>\n                                                                                    <\/div>\n                                                                                                                            <div class=\"btn-wraper\">\n                                    \n                                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2022\/04\/18\/analyza-skupiny-detskych-pacientu-s-relabujici-roztrousenou-sklerozou-udaje-z-ceskeho-narodniho-registru\/\" class=\"elementskit-btn  whitespace--normal\" >\n                                                                                    P\u0159e\u010d\u00edst v\u00edce                                         <\/a>\n                                                                    <\/div>\n                                                    <\/div><!-- .elementskit-post-body END -->\n                    <\/div>\n                \n            <\/div>\t\t\t\t\n\n            <div class=\"col-lg-12 col-md-12\">\n\n                                    <div class=\"elementskit-post-image-card\">\n                        <div class=\"elementskit-entry-header\">\n                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2021\/11\/28\/je-tehotenstvi-u-pacientek-s-rs-bezpecne-a-jaky-ma-vliv-na-prubeh-rs-realne-poznatky-z-1-533-tehotenstvi-v-ceske-republice\/\" class=\"elementskit-entry-thumb\">\n                                    <img decoding=\"async\" src=\"\/wp-content\/uploads\/2021\/11\/pregnancy_and_MS.jpg\" alt=\"Je t\u011bhotenstv\u00ed u pacientek s RS bezpe\u010dn\u00e9 a jak\u00fd m\u00e1 vliv na pr\u016fb\u011bh RS? Re\u00e1ln\u00e9 poznatky z 1 533 t\u011bhotenstv\u00ed v \u010cesk\u00e9 republice\">\n                                <\/a><!-- .elementskit-entry-thumb END -->\n                                                            \n                            \n                                                    <\/div><!-- .elementskit-entry-header END -->\n\n                        <div class=\"elementskit-post-body \">\n                            \n                                        \n                                        \t\t\t\t\t\t\t\t\t\t                <h2 class=\"entry-title\">\n                    <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2021\/11\/28\/je-tehotenstvi-u-pacientek-s-rs-bezpecne-a-jaky-ma-vliv-na-prubeh-rs-realne-poznatky-z-1-533-tehotenstvi-v-ceske-republice\/\">\n                            Je t\u011bhotenstv\u00ed u pacientek s RS bezpe\u010dn\u00e9 a jak\u00fd m\u00e1 vliv na pr\u016fb\u011bh RS? Re\u00e1ln\u00e9 poznatky z 1 533 t\u011bhotenstv\u00ed v \u010cesk\u00e9 republice                    <\/a>\n                <\/h2>\n                                                        \n                                                                                                                                                                            <p>T\u011bhotenstv\u00ed u pacientek s roztrou\u0161enou skler\u00f3zou (RS) vy\u017eaduje zvl\u00e1\u0161tn\u00ed p\u00e9\u010di, zejm\u00e9na pokud jde o rozhodov\u00e1n\u00ed ohledn\u011b l\u00e9\u010dby modifikuj\u00edc\u00ed onemocn\u011bn\u00ed (DMD) a poradenstv\u00ed t\u00fdkaj\u00edc\u00ed se obdob\u00ed po\u010det\u00ed, t\u011bhotenstv\u00ed a poporodn\u00edho obdob\u00ed. Tato studie se zam\u011b\u0159uje na anal\u00fdzu vlivu t\u011bhotenstv\u00ed, porodu nebo potratu na pr\u016fb\u011bh roztrou\u0161en\u00e9 skler\u00f3zy&#8230;<\/p>\n                                                                                                                                                                <div class=\"post-meta-list\">\n                                                                                                <span class=\"meta-date\">\n\n                                <i aria-hidden=\"true\" class=\"icon icon-calendar3\"><\/i>\n                                <span class=\"meta-date-text\">\n                                    28. 11. 2021                                <\/span>\n                            <\/span>\n                                                                                                                                                                                                <span class=\"post-cat\">\n\n                                \n\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/category\/publikace\/\" rel=\"category tag\">publikace<\/a>\n                            <\/span>\n                                                                                    <\/div>\n                                                                                                                            <div class=\"btn-wraper\">\n                                    \n                                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2021\/11\/28\/je-tehotenstvi-u-pacientek-s-rs-bezpecne-a-jaky-ma-vliv-na-prubeh-rs-realne-poznatky-z-1-533-tehotenstvi-v-ceske-republice\/\" class=\"elementskit-btn  whitespace--normal\" >\n                                                                                    P\u0159e\u010d\u00edst v\u00edce                                         <\/a>\n                                                                    <\/div>\n                                                    <\/div><!-- .elementskit-post-body END -->\n                    <\/div>\n                \n            <\/div>\t\t\t\t\n\n            <div class=\"col-lg-12 col-md-12\">\n\n                                    <div class=\"elementskit-post-image-card\">\n                        <div class=\"elementskit-entry-header\">\n                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2021\/06\/24\/roztrousena-skleroza-neuromyelitis-optica-a-covid-19-pandemicky-rok-v-cesku\/\" class=\"elementskit-entry-thumb\">\n                                    <img decoding=\"async\" src=\"\/wp-content\/uploads\/2021\/06\/covid19_face_mask.jpg\" alt=\"Roztrou\u0161en\u00e1 skler\u00f3za, neuromyelitis optica a COVID-19: Pandemick\u00fd rok v \u010cesku\">\n                                <\/a><!-- .elementskit-entry-thumb END -->\n                                                            \n                            \n                                                    <\/div><!-- .elementskit-entry-header END -->\n\n                        <div class=\"elementskit-post-body \">\n                            \n                                        \n                                        \t\t\t\t\t\t\t\t\t\t                <h2 class=\"entry-title\">\n                    <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2021\/06\/24\/roztrousena-skleroza-neuromyelitis-optica-a-covid-19-pandemicky-rok-v-cesku\/\">\n                            Roztrou\u0161en\u00e1 skler\u00f3za, neuromyelitis optica a COVID-19: Pandemick\u00fd rok v \u010cesku                    <\/a>\n                <\/h2>\n                                                        \n                                                                                                                                                                            <p>Vzhledem k v\u00fdskytu nov\u00e9ho koronaviru COVID-19 vznikly obavy ohledn\u011b pr\u016fb\u011bhu tohoto onemocn\u011bn\u00ed u pacient\u016f s roztrou\u0161enou skler\u00f3zou (RS) a neuromyelitis optica spectrum disorder (NMOSD). Tato studie si kladla za c\u00edl vyhodnotit v\u00fdskyt, z\u00e1va\u017enost a rizikov\u00e9 faktory pro z\u00e1va\u017en\u011bj\u0161\u00ed pr\u016fb\u011bh COVID-19 mezi pacienty s RS a NMOSD&#8230;<\/p>\n                                                                                                                                                                <div class=\"post-meta-list\">\n                                                                                                <span class=\"meta-date\">\n\n                                <i aria-hidden=\"true\" class=\"icon icon-calendar3\"><\/i>\n                                <span class=\"meta-date-text\">\n                                    24. 6. 2021                                <\/span>\n                            <\/span>\n                                                                                                                                                                                                <span class=\"post-cat\">\n\n                                \n\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/category\/publikace\/\" rel=\"category tag\">publikace<\/a>\n                            <\/span>\n                                                                                    <\/div>\n                                                                                                                            <div class=\"btn-wraper\">\n                                    \n                                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2021\/06\/24\/roztrousena-skleroza-neuromyelitis-optica-a-covid-19-pandemicky-rok-v-cesku\/\" class=\"elementskit-btn  whitespace--normal\" >\n                                                                                    P\u0159e\u010d\u00edst v\u00edce                                         <\/a>\n                                                                    <\/div>\n                                                    <\/div><!-- .elementskit-post-body END -->\n                    <\/div>\n                \n            <\/div>\t\t\t\t\n\n            <div class=\"col-lg-12 col-md-12\">\n\n                                    <div class=\"elementskit-post-image-card\">\n                        <div class=\"elementskit-entry-header\">\n                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2021\/05\/25\/covid-19-a-roztrousena-skleroza-pod-drobnohledem\/\" class=\"elementskit-entry-thumb\">\n                                    <img decoding=\"async\" src=\"\/wp-content\/uploads\/2021\/05\/TK_2021_header2.jpg\" alt=\"Covid-19 a roztrou\u0161en\u00e1 skler\u00f3za pod drobnohledem | Tiskov\u00e1 konference registru ReMuS 2021\">\n                                <\/a><!-- .elementskit-entry-thumb END -->\n                                                            \n                            \n                                                    <\/div><!-- .elementskit-entry-header END -->\n\n                        <div class=\"elementskit-post-body \">\n                            \n                                        \n                                        \t\t\t\t\t\t\t\t\t\t                <h2 class=\"entry-title\">\n                    <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2021\/05\/25\/covid-19-a-roztrousena-skleroza-pod-drobnohledem\/\">\n                            Covid-19 a roztrou\u0161en\u00e1 skler\u00f3za pod drobnohledem | Tiskov\u00e1 konference registru ReMuS 2021                    <\/a>\n                <\/h2>\n                                                        \n                                                                                                                                                                            <p>P\u0159esn\u011b 1918 pacient\u016f s roztrou\u0161enou skler\u00f3zou (RS), kte\u0159\u00ed z\u00e1rove\u0148 onemocn\u011bli koronavirem, podrobn\u011b sleduj\u00ed l\u00e9ka\u0159i v Registru pacient\u016f s roztrou\u0161enou skler\u00f3zou ReMuS. Od b\u0159ezna lo\u0148sk\u00e9ho roku zkoumaj\u00ed symptomy, l\u00e9\u010dbu i p\u0159\u00edpadn\u00fd vliv koronaviru na tuto specifickou skupinu lid\u00ed. Prvn\u00ed anal\u00fdzy ukazuj\u00ed, \u017ee RS nen\u00ed rizikov\u00fdm faktorem, ve vy\u0161\u0161\u00edm riziku se v\u0161ak ocitaj\u00ed pacienti star\u0161\u00ed, s t\u011b\u017e\u0161\u00edm neurologick\u00fdm posti\u017een\u00edm, ob\u00e9zn\u00ed a tak\u00e9 pacienti s ur\u010dit\u00fdm typem chronick\u00e9 terapie&#8230;<\/p>\n                                                                                                                                                                <div class=\"post-meta-list\">\n                                                                                                <span class=\"meta-date\">\n\n                                <i aria-hidden=\"true\" class=\"icon icon-calendar3\"><\/i>\n                                <span class=\"meta-date-text\">\n                                    25. 5. 2021                                <\/span>\n                            <\/span>\n                                                                                                                                                                                                <span class=\"post-cat\">\n\n                                \n\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/category\/akce\/\" rel=\"category tag\">akce<\/a> | <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/category\/publikace\/\" rel=\"category tag\">publikace<\/a>\n                            <\/span>\n                                                                                    <\/div>\n                                                                                                                            <div class=\"btn-wraper\">\n                                    \n                                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2021\/05\/25\/covid-19-a-roztrousena-skleroza-pod-drobnohledem\/\" class=\"elementskit-btn  whitespace--normal\" >\n                                                                                    P\u0159e\u010d\u00edst v\u00edce                                         <\/a>\n                                                                    <\/div>\n                                                    <\/div><!-- .elementskit-post-body END -->\n                    <\/div>\n                \n            <\/div>\t\t\t\t\n\n            <div class=\"col-lg-12 col-md-12\">\n\n                                    <div class=\"elementskit-post-image-card\">\n                        <div class=\"elementskit-entry-header\">\n                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2021\/03\/17\/roztrousena-skleroza-neuromyelitis-optica-a-covid-19-pandemicky-rok-v-ceskuzmena-lecby-a-preruseni-lecby-v-prubehu-20-let-ve-skupine-registru-big-multiple-sclerosis-data-network\/\" class=\"elementskit-entry-thumb\">\n                                    <img decoding=\"async\" src=\"\/wp-content\/uploads\/2021\/03\/BMSD_discontinuations1.jpg\" alt=\"Zm\u011bna l\u00e9\u010dby a p\u0159eru\u0161en\u00ed l\u00e9\u010dby v pr\u016fb\u011bhu 20 let ve skupin\u011b registr\u016f Big Multiple Sclerosis Data Network\u200b\">\n                                <\/a><!-- .elementskit-entry-thumb END -->\n                                                            \n                            \n                                                    <\/div><!-- .elementskit-entry-header END -->\n\n                        <div class=\"elementskit-post-body \">\n                            \n                                        \n                                        \t\t\t\t\t\t\t\t\t\t                <h2 class=\"entry-title\">\n                    <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2021\/03\/17\/roztrousena-skleroza-neuromyelitis-optica-a-covid-19-pandemicky-rok-v-ceskuzmena-lecby-a-preruseni-lecby-v-prubehu-20-let-ve-skupine-registru-big-multiple-sclerosis-data-network\/\">\n                            Zm\u011bna l\u00e9\u010dby a p\u0159eru\u0161en\u00ed l\u00e9\u010dby v pr\u016fb\u011bhu 20 let ve skupin\u011b registr\u016f Big Multiple Sclerosis Data Network\u200b                    <\/a>\n                <\/h2>\n                                                        \n                                                                                                                                                                            <p>Tato studie se zam\u011b\u0159uje na popis p\u0159eru\u0161en\u00ed a ukon\u010den\u00ed l\u00e9\u010dby ve skupin\u011b registr\u016f Big Multiple Sclerosis Data Network. V r\u00e1mci t\u00e9to kohortov\u00e9 studie byla pod veden\u00edm prof. Jana Hillerta ze \u0161v\u00e9dsk\u00e9 univerzity Karolinska Institutet slou\u010dena data z p\u011bti klinick\u00fdch registr\u016f, kter\u00e9 pokr\u00fdvaj\u00ed obdob\u00ed 20 let&#8230;.<\/p>\n                                                                                                                                                                <div class=\"post-meta-list\">\n                                                                                                <span class=\"meta-date\">\n\n                                <i aria-hidden=\"true\" class=\"icon icon-calendar3\"><\/i>\n                                <span class=\"meta-date-text\">\n                                    17. 3. 2021                                <\/span>\n                            <\/span>\n                                                                                                                                                                                                <span class=\"post-cat\">\n\n                                \n\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/category\/publikace\/\" rel=\"category tag\">publikace<\/a>\n                            <\/span>\n                                                                                    <\/div>\n                                                                                                                            <div class=\"btn-wraper\">\n                                    \n                                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2021\/03\/17\/roztrousena-skleroza-neuromyelitis-optica-a-covid-19-pandemicky-rok-v-ceskuzmena-lecby-a-preruseni-lecby-v-prubehu-20-let-ve-skupine-registru-big-multiple-sclerosis-data-network\/\" class=\"elementskit-btn  whitespace--normal\" >\n                                                                                    P\u0159e\u010d\u00edst v\u00edce                                         <\/a>\n                                                                    <\/div>\n                                                    <\/div><!-- .elementskit-post-body END -->\n                    <\/div>\n                \n            <\/div>\t\t\t\t\n\n            <div class=\"col-lg-12 col-md-12\">\n\n                                    <div class=\"elementskit-post-image-card\">\n                        <div class=\"elementskit-entry-header\">\n                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2021\/01\/12\/srovnani-terapie-u-pacientu-s-rs-po-prvni-demyelinizacni-prihode-v-realne-klinicke-praxi-v-ceske-republice-udaje-z-narodniho-registru-remus\/\" class=\"elementskit-entry-thumb\">\n                                    <img decoding=\"async\" src=\"\/wp-content\/uploads\/2021\/01\/PAVELEK_2021_frontiers.jpg\" alt=\"Srovn\u00e1n\u00ed terapie u pacient\u016f s RS po prvn\u00ed demyeliniza\u010dn\u00ed p\u0159\u00edhod\u011b v re\u00e1ln\u00e9 klinick\u00e9 praxi v \u010cesk\u00e9 republice: \u00dadaje z n\u00e1rodn\u00edho registru ReMuS\">\n                                <\/a><!-- .elementskit-entry-thumb END -->\n                                                            \n                            \n                                                    <\/div><!-- .elementskit-entry-header END -->\n\n                        <div class=\"elementskit-post-body \">\n                            \n                                        \n                                        \t\t\t\t\t\t\t\t\t\t                <h2 class=\"entry-title\">\n                    <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2021\/01\/12\/srovnani-terapie-u-pacientu-s-rs-po-prvni-demyelinizacni-prihode-v-realne-klinicke-praxi-v-ceske-republice-udaje-z-narodniho-registru-remus\/\">\n                            Srovn\u00e1n\u00ed terapie u pacient\u016f s RS po prvn\u00ed demyeliniza\u010dn\u00ed p\u0159\u00edhod\u011b v re\u00e1ln\u00e9 klinick\u00e9 praxi v \u010cesk\u00e9 republice: \u00dadaje z n\u00e1rodn\u00edho registru ReMuS                    <\/a>\n                <\/h2>\n                                                        \n                                                                                                                                                                            <p>Roztrou\u0161en\u00e1 skler\u00f3za (RS) je chronick\u00e9 z\u00e1n\u011btliv\u00e9 a neurodegenerativn\u00ed onemocn\u011bn\u00ed centr\u00e1ln\u00edho nervov\u00e9ho syst\u00e9mu. Po prvn\u00ed demyeliniza\u010dn\u00ed p\u0159\u00edhod\u011b se v \u010cesk\u00e9 republice u pacient\u016f s RS b\u011b\u017en\u011b pou\u017e\u00edvaj\u00ed dob\u0159e zaveden\u00e9 l\u00e9ky&#8230;<\/p>\n                                                                                                                                                                <div class=\"post-meta-list\">\n                                                                                                <span class=\"meta-date\">\n\n                                <i aria-hidden=\"true\" class=\"icon icon-calendar3\"><\/i>\n                                <span class=\"meta-date-text\">\n                                    12. 1. 2021                                <\/span>\n                            <\/span>\n                                                                                                                                                                                                <span class=\"post-cat\">\n\n                                \n\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/category\/publikace\/\" rel=\"category tag\">publikace<\/a>\n                            <\/span>\n                                                                                    <\/div>\n                                                                                                                            <div class=\"btn-wraper\">\n                                    \n                                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2021\/01\/12\/srovnani-terapie-u-pacientu-s-rs-po-prvni-demyelinizacni-prihode-v-realne-klinicke-praxi-v-ceske-republice-udaje-z-narodniho-registru-remus\/\" class=\"elementskit-btn  whitespace--normal\" >\n                                                                                    P\u0159e\u010d\u00edst v\u00edce                                         <\/a>\n                                                                    <\/div>\n                                                    <\/div><!-- .elementskit-post-body END -->\n                    <\/div>\n                \n            <\/div>\t\t\t\t\n\n            <div class=\"col-lg-12 col-md-12\">\n\n                                    <div class=\"elementskit-post-image-card\">\n                        <div class=\"elementskit-entry-header\">\n                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2020\/10\/15\/jaka-data-nabizi-celostatni-registr-pacientu-s-roztrousenou-sklerozou-remus\/\" class=\"elementskit-entry-thumb\">\n                                    <img decoding=\"async\" src=\"\/wp-content\/uploads\/2020\/10\/NPP_Horakova_2020_image.jpg\" alt=\"Jak\u00e1 data nab\u00edz\u00ed celost\u00e1tn\u00ed registr pacient\u016f s roztrou\u0161enou skler\u00f3zou ReMuS?\">\n                                <\/a><!-- .elementskit-entry-thumb END -->\n                                                            \n                            \n                                                    <\/div><!-- .elementskit-entry-header END -->\n\n                        <div class=\"elementskit-post-body \">\n                            \n                                        \n                                        \t\t\t\t\t\t\t\t\t\t                <h2 class=\"entry-title\">\n                    <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2020\/10\/15\/jaka-data-nabizi-celostatni-registr-pacientu-s-roztrousenou-sklerozou-remus\/\">\n                            Jak\u00e1 data nab\u00edz\u00ed celost\u00e1tn\u00ed registr pacient\u016f s roztrou\u0161enou skler\u00f3zou ReMuS?                    <\/a>\n                <\/h2>\n                                                        \n                                                                                                                                                                            <p>V p\u0159ehledov\u00e9m \u010dl\u00e1nku odborn\u00e9ho \u010dasopisu Neurologie pro praxi se odborn\u00e1 garantka registru ReMuS zam\u011b\u0159ila na p\u0159edstaven\u00ed registru ReMuS a zejm\u00e9na \u0161k\u00e1ly dat v n\u011bm obsa\u017een\u00fdch. \u010cl\u00e1nek nab\u00edz\u00ed tak\u00e9 pohled na zastoupen\u00ed pacient\u016f v jednotliv\u00fdch RS centrech \u010cesk\u00e9 republiky, v\u00fdvoj nasazov\u00e1n\u00ed vysoce \u00fa\u010dinn\u00fdch l\u00e9\u010div\u00fdch p\u0159\u00edpravk\u016f nebo velmi d\u016fle\u017eitou oblast&#8230;<\/p>\n                                                                                                                                                                <div class=\"post-meta-list\">\n                                                                                                <span class=\"meta-date\">\n\n                                <i aria-hidden=\"true\" class=\"icon icon-calendar3\"><\/i>\n                                <span class=\"meta-date-text\">\n                                    15. 10. 2020                                <\/span>\n                            <\/span>\n                                                                                                                                                                                                <span class=\"post-cat\">\n\n                                \n\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/category\/publikace\/\" rel=\"category tag\">publikace<\/a>\n                            <\/span>\n                                                                                    <\/div>\n                                                                                                                            <div class=\"btn-wraper\">\n                                    \n                                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2020\/10\/15\/jaka-data-nabizi-celostatni-registr-pacientu-s-roztrousenou-sklerozou-remus\/\" class=\"elementskit-btn  whitespace--normal\" >\n                                                                                    P\u0159e\u010d\u00edst v\u00edce                                         <\/a>\n                                                                    <\/div>\n                                                    <\/div><!-- .elementskit-post-body END -->\n                    <\/div>\n                \n            <\/div>\t\t\t\t\n\n            <div class=\"col-lg-12 col-md-12\">\n\n                                    <div class=\"elementskit-post-image-card\">\n                        <div class=\"elementskit-entry-header\">\n                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2019\/09\/21\/registr-pacientu-s-roztrousenou-sklerozou-remus-vyznam-dat-u-chronickych-onemocneni\/\" class=\"elementskit-entry-thumb\">\n                                    <img decoding=\"async\" src=\"\/wp-content\/uploads\/2019\/09\/2019_Horakova_Remedia_image.jpg\" alt=\"Registr pacient\u016f s roztrou\u0161enou skler\u00f3zou ReMuS \u2013 v\u00fdznam dat u chronick\u00fdch onemocn\u011bn\u00ed\">\n                                <\/a><!-- .elementskit-entry-thumb END -->\n                                                            \n                            \n                                                    <\/div><!-- .elementskit-entry-header END -->\n\n                        <div class=\"elementskit-post-body \">\n                            \n                                        \n                                        \t\t\t\t\t\t\t\t\t\t                <h2 class=\"entry-title\">\n                    <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2019\/09\/21\/registr-pacientu-s-roztrousenou-sklerozou-remus-vyznam-dat-u-chronickych-onemocneni\/\">\n                            Registr pacient\u016f s roztrou\u0161enou skler\u00f3zou ReMuS \u2013 v\u00fdznam dat u chronick\u00fdch onemocn\u011bn\u00ed                    <\/a>\n                <\/h2>\n                                                        \n                                                                                                                                                                            <p>Nov\u00fd \u010dl\u00e1nek v odborn\u00e9m \u010dasopisu Remedia p\u0159in\u00e1\u0161\u00ed informace o tom, co lze po \u0161esti letech fungov\u00e1n\u00ed naj\u00edt v datech registru pacient\u016f s roztrou\u0161enou skler\u00f3zou ReMuS i re\u00e1ln\u00e9 klinick\u00e9 praxi \u010cesk\u00e9 republiky. Od sv\u00e9ho vzniku jsou k dispozici z\u00e1znamy&#8230;<\/p>\n                                                                                                                                                                <div class=\"post-meta-list\">\n                                                                                                <span class=\"meta-date\">\n\n                                <i aria-hidden=\"true\" class=\"icon icon-calendar3\"><\/i>\n                                <span class=\"meta-date-text\">\n                                    21. 9. 2019                                <\/span>\n                            <\/span>\n                                                                                                                                                                                                <span class=\"post-cat\">\n\n                                \n\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/category\/publikace\/\" rel=\"category tag\">publikace<\/a>\n                            <\/span>\n                                                                                    <\/div>\n                                                                                                                            <div class=\"btn-wraper\">\n                                    \n                                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2019\/09\/21\/registr-pacientu-s-roztrousenou-sklerozou-remus-vyznam-dat-u-chronickych-onemocneni\/\" class=\"elementskit-btn  whitespace--normal\" >\n                                                                                    P\u0159e\u010d\u00edst v\u00edce                                         <\/a>\n                                                                    <\/div>\n                                                    <\/div><!-- .elementskit-post-body END -->\n                    <\/div>\n                \n            <\/div>\t\t\t\t\n\n            <div class=\"col-lg-12 col-md-12\">\n\n                                    <div class=\"elementskit-post-image-card\">\n                        <div class=\"elementskit-entry-header\">\n                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2019\/08\/03\/zahajeni-prvni-chorobu-modifikujici-lecby-u-pacientu-s-roztrousenou-sklerozou-v-ceske-republice-v-letech-2013-2016-udaje-z-narodniho-registru-remus\/\" class=\"elementskit-entry-thumb\">\n                                    <img decoding=\"async\" src=\"\/wp-content\/uploads\/2019\/08\/2019_Horakova_MSARD_header1.jpg\" alt=\"Zah\u00e1jen\u00ed prvn\u00ed chorobu modifikuj\u00edc\u00ed l\u00e9\u010dby u pacient\u016f s roztrou\u0161enou skler\u00f3zou v \u010cesk\u00e9 republice v letech 2013-2016: \u00dadaje z n\u00e1rodn\u00edho registru ReMuS\u200b\">\n                                <\/a><!-- .elementskit-entry-thumb END -->\n                                                            \n                            \n                                                    <\/div><!-- .elementskit-entry-header END -->\n\n                        <div class=\"elementskit-post-body \">\n                            \n                                        \n                                        \t\t\t\t\t\t\t\t\t\t                <h2 class=\"entry-title\">\n                    <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2019\/08\/03\/zahajeni-prvni-chorobu-modifikujici-lecby-u-pacientu-s-roztrousenou-sklerozou-v-ceske-republice-v-letech-2013-2016-udaje-z-narodniho-registru-remus\/\">\n                            Zah\u00e1jen\u00ed prvn\u00ed chorobu modifikuj\u00edc\u00ed l\u00e9\u010dby u pacient\u016f s roztrou\u0161enou skler\u00f3zou v \u010cesk\u00e9 republice v letech 2013-2016: \u00dadaje z n\u00e1rodn\u00edho registru ReMuS\u200b                    <\/a>\n                <\/h2>\n                                                        \n                                                                                                                                                                            <p>Spr\u00e1vn\u00fd management l\u00e9\u010dby roztrou\u0161en\u00e9 skler\u00f3zy (RS) vy\u017eaduje zp\u011btnou vazbu z klinick\u00e9 praxe, kterou poskytuj\u00ed registry. Tento \u010dl\u00e1nek se zam\u011b\u0159uje na p\u0159edstaven\u00ed \u010desk\u00e9ho n\u00e1rodn\u00edho registru roztrou\u0161en\u00e9 skler\u00f3zy, ReMuS, a zkoum\u00e1 dostupnost a vyu\u017e\u00edv\u00e1n\u00ed l\u00e9k\u016f&#8230;<\/p>\n                                                                                                                                                                <div class=\"post-meta-list\">\n                                                                                                <span class=\"meta-date\">\n\n                                <i aria-hidden=\"true\" class=\"icon icon-calendar3\"><\/i>\n                                <span class=\"meta-date-text\">\n                                    3. 8. 2019                                <\/span>\n                            <\/span>\n                                                                                                                                                                                                <span class=\"post-cat\">\n\n                                \n\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/category\/publikace\/\" rel=\"category tag\">publikace<\/a>\n                            <\/span>\n                                                                                    <\/div>\n                                                                                                                            <div class=\"btn-wraper\">\n                                    \n                                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2019\/08\/03\/zahajeni-prvni-chorobu-modifikujici-lecby-u-pacientu-s-roztrousenou-sklerozou-v-ceske-republice-v-letech-2013-2016-udaje-z-narodniho-registru-remus\/\" class=\"elementskit-btn  whitespace--normal\" >\n                                                                                    P\u0159e\u010d\u00edst v\u00edce                                         <\/a>\n                                                                    <\/div>\n                                                    <\/div><!-- .elementskit-post-body END -->\n                    <\/div>\n                \n            <\/div>\t\t\t\t\n\n            <div class=\"col-lg-12 col-md-12\">\n\n                                    <div class=\"elementskit-post-image-card\">\n                        <div class=\"elementskit-entry-header\">\n                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2018\/12\/10\/jaka-data-nabizi-celostatni-registr-pacientu-s-roztrousenou-sklerozou-remus-2\/\" class=\"elementskit-entry-thumb\">\n                                    <img decoding=\"async\" src=\"\/wp-content\/uploads\/2018\/12\/2018_Horakova_NPP_header.jpg\" alt=\"Kam jsme se posunuli za p\u011bt let existence registru ReMuS\">\n                                <\/a><!-- .elementskit-entry-thumb END -->\n                                                            \n                            \n                                                    <\/div><!-- .elementskit-entry-header END -->\n\n                        <div class=\"elementskit-post-body \">\n                            \n                                        \n                                        \t\t\t\t\t\t\t\t\t\t                <h2 class=\"entry-title\">\n                    <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2018\/12\/10\/jaka-data-nabizi-celostatni-registr-pacientu-s-roztrousenou-sklerozou-remus-2\/\">\n                            Kam jsme se posunuli za p\u011bt let existence registru ReMuS                    <\/a>\n                <\/h2>\n                                                        \n                                                                                                                                                                            <p>Za p\u011bt let sv\u00e9 existence se \u010desk\u00fd n\u00e1rodn\u00ed registr pacient\u016f s roztrou\u0161enou skler\u00f3zou, ReMuS, stal neoceniteln\u00fdm zdrojem dat pro klinickou praxi i v\u00fdzkum. Tento \u010dl\u00e1nek p\u0159in\u00e1\u0161\u00ed p\u0159ehled o tom, jak\u00fdm zp\u016fsobem se registr vyvinul od sv\u00e9ho vzniku v roce 2013&#8230;<\/p>\n                                                                                                                                                                <div class=\"post-meta-list\">\n                                                                                                <span class=\"meta-date\">\n\n                                <i aria-hidden=\"true\" class=\"icon icon-calendar3\"><\/i>\n                                <span class=\"meta-date-text\">\n                                    10. 12. 2018                                <\/span>\n                            <\/span>\n                                                                                                                                                                                                <span class=\"post-cat\">\n\n                                \n\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/category\/publikace\/\" rel=\"category tag\">publikace<\/a>\n                            <\/span>\n                                                                                    <\/div>\n                                                                                                                            <div class=\"btn-wraper\">\n                                    \n                                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2018\/12\/10\/jaka-data-nabizi-celostatni-registr-pacientu-s-roztrousenou-sklerozou-remus-2\/\" class=\"elementskit-btn  whitespace--normal\" >\n                                                                                    P\u0159e\u010d\u00edst v\u00edce                                         <\/a>\n                                                                    <\/div>\n                                                    <\/div><!-- .elementskit-post-body END -->\n                    <\/div>\n                \n            <\/div>\t\t\t\t\n\n            <div class=\"col-lg-12 col-md-12\">\n\n                                    <div class=\"elementskit-post-image-card\">\n                        <div class=\"elementskit-entry-header\">\n                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2018\/10\/04\/registry-roztrousene-sklerozy-v-evrope-aktualizovany-prehled\/\" class=\"elementskit-entry-thumb\">\n                                    <img decoding=\"async\" src=\"\/wp-content\/uploads\/2018\/10\/2019_Glaser_MSARD_header1.jpg\" alt=\"Registry roztrou\u0161en\u00e9 skler\u00f3zy v Evrop\u011b &#8211; Aktualizovan\u00fd p\u0159ehled\">\n                                <\/a><!-- .elementskit-entry-thumb END -->\n                                                            \n                            \n                                                    <\/div><!-- .elementskit-entry-header END -->\n\n                        <div class=\"elementskit-post-body \">\n                            \n                                        \n                                        \t\t\t\t\t\t\t\t\t\t                <h2 class=\"entry-title\">\n                    <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2018\/10\/04\/registry-roztrousene-sklerozy-v-evrope-aktualizovany-prehled\/\">\n                            Registry roztrou\u0161en\u00e9 skler\u00f3zy v Evrop\u011b &#8211; Aktualizovan\u00fd p\u0159ehled                    <\/a>\n                <\/h2>\n                                                        \n                                                                                                                                                                            <p>V roce 2018 bylo provedeno aktualizovan\u00e9 mapov\u00e1n\u00ed registr\u016f roztrou\u0161en\u00e9 skler\u00f3zy (RS) v Evrop\u011b, kter\u00e9 nav\u00e1zalo na p\u0159edchoz\u00ed pr\u016fzkum z roku 2014. Tento pr\u016fzkum zahrnuje 19 registr\u016f, p\u0159ev\u00e1\u017en\u011b z Evropy, a poskytuje podrobn\u00e9 informace o organizaci, metod\u00e1ch sb\u011bru dat, kvalit\u011b kontroln\u00edch mechanism\u016f a financov\u00e1n\u00ed&#8230;<\/p>\n                                                                                                                                                                <div class=\"post-meta-list\">\n                                                                                                <span class=\"meta-date\">\n\n                                <i aria-hidden=\"true\" class=\"icon icon-calendar3\"><\/i>\n                                <span class=\"meta-date-text\">\n                                    4. 10. 2018                                <\/span>\n                            <\/span>\n                                                                                                                                                                                                <span class=\"post-cat\">\n\n                                \n\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/category\/publikace\/\" rel=\"category tag\">publikace<\/a>\n                            <\/span>\n                                                                                    <\/div>\n                                                                                                                            <div class=\"btn-wraper\">\n                                    \n                                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2018\/10\/04\/registry-roztrousene-sklerozy-v-evrope-aktualizovany-prehled\/\" class=\"elementskit-btn  whitespace--normal\" >\n                                                                                    P\u0159e\u010d\u00edst v\u00edce                                         <\/a>\n                                                                    <\/div>\n                                                    <\/div><!-- .elementskit-post-body END -->\n                    <\/div>\n                \n            <\/div>\t\t\t\t\n\n            <div class=\"col-lg-12 col-md-12\">\n\n                                    <div class=\"elementskit-post-image-card\">\n                        <div class=\"elementskit-entry-header\">\n                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2018\/06\/07\/srovnani-ucinnosti-subkutanne-podavaneho-interferonu-%ce%b2-1a-44-%ce%bcg-dimetyl-fumaratu-a-fingolimodu-v-realne-klinicke-praxi-multicentricka-observacni-studie\/\" class=\"elementskit-entry-thumb\">\n                                    <img decoding=\"async\" src=\"\/wp-content\/uploads\/2018\/06\/2018_Pavelek_CSNN_header1.jpg\" alt=\"Srovn\u00e1n\u00ed \u00fa\u010dinnosti subkut\u00e1nn\u011b pod\u00e1van\u00e9ho interferonu \u03b2-1a 44 \u03bcg, dimetyl fumar\u00e1tu a fingolimodu v re\u00e1ln\u00e9 klinick\u00e9 praxi \u2013 multicentrick\u00e1 observa\u010dn\u00ed studie\">\n                                <\/a><!-- .elementskit-entry-thumb END -->\n                                                            \n                            \n                                                    <\/div><!-- .elementskit-entry-header END -->\n\n                        <div class=\"elementskit-post-body \">\n                            \n                                        \n                                        \t\t\t\t\t\t\t\t\t\t                <h2 class=\"entry-title\">\n                    <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2018\/06\/07\/srovnani-ucinnosti-subkutanne-podavaneho-interferonu-%ce%b2-1a-44-%ce%bcg-dimetyl-fumaratu-a-fingolimodu-v-realne-klinicke-praxi-multicentricka-observacni-studie\/\">\n                            Srovn\u00e1n\u00ed \u00fa\u010dinnosti subkut\u00e1nn\u011b pod\u00e1van\u00e9ho interferonu \u03b2-1a 44 \u03bcg, dimetyl fumar\u00e1tu a fingolimodu v re\u00e1ln\u00e9 klinick\u00e9 praxi \u2013 multicentrick\u00e1 observa\u010dn\u00ed studie                    <\/a>\n                <\/h2>\n                                                        \n                                                                                                                                                                            <p>Roztrou\u0161en\u00e1 skler\u00f3za (RS) je chronick\u00e9 z\u00e1n\u011btliv\u00e9 demyeliniza\u010dn\u00ed a neurodegenerativn\u00ed onemocn\u011bn\u00ed postihuj\u00edc\u00ed centr\u00e1ln\u00ed nervov\u00fd syst\u00e9m. Interferon (IFN) \u03b2-1a 44 \u03bcg, dimethyl fumar\u00e1t (DMF) a fingolimod jsou zaveden\u00e9 l\u00e9ky pro l\u00e9\u010dbu relaps-remituj\u00edc\u00ed RS (RR RS). C\u00edlem tohoto projektu, kter\u00fd zahrnuje anal\u00fdzu dat z registru ReMuS, bylo porovnat&#8230;<\/p>\n                                                                                                                                                                <div class=\"post-meta-list\">\n                                                                                                <span class=\"meta-date\">\n\n                                <i aria-hidden=\"true\" class=\"icon icon-calendar3\"><\/i>\n                                <span class=\"meta-date-text\">\n                                    7. 6. 2018                                <\/span>\n                            <\/span>\n                                                                                                                                                                                                <span class=\"post-cat\">\n\n                                \n\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/category\/publikace\/\" rel=\"category tag\">publikace<\/a>\n                            <\/span>\n                                                                                    <\/div>\n                                                                                                                            <div class=\"btn-wraper\">\n                                    \n                                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2018\/06\/07\/srovnani-ucinnosti-subkutanne-podavaneho-interferonu-%ce%b2-1a-44-%ce%bcg-dimetyl-fumaratu-a-fingolimodu-v-realne-klinicke-praxi-multicentricka-observacni-studie\/\" class=\"elementskit-btn  whitespace--normal\" >\n                                                                                    P\u0159e\u010d\u00edst v\u00edce                                         <\/a>\n                                                                    <\/div>\n                                                    <\/div><!-- .elementskit-post-body END -->\n                    <\/div>\n                \n            <\/div>\t\t\t\t\n\n            <div class=\"col-lg-12 col-md-12\">\n\n                                    <div class=\"elementskit-post-image-card\">\n                        <div class=\"elementskit-entry-header\">\n                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2016\/11\/15\/remus-cesky-celostatni-registr-pacientu-s-roztrousenou-sklerozou\/\" class=\"elementskit-entry-thumb\">\n                                    <img decoding=\"async\" src=\"\/wp-content\/uploads\/2016\/11\/2016_Horakova_MSN_header.jpg\" alt=\"ReMuS \u2013 \u010desk\u00fd celost\u00e1tn\u00ed registr pacient\u016f s roztrou\u0161enou skler\u00f3zou\">\n                                <\/a><!-- .elementskit-entry-thumb END -->\n                                                            \n                            \n                                                    <\/div><!-- .elementskit-entry-header END -->\n\n                        <div class=\"elementskit-post-body \">\n                            \n                                        \n                                        \t\t\t\t\t\t\t\t\t\t                <h2 class=\"entry-title\">\n                    <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2016\/11\/15\/remus-cesky-celostatni-registr-pacientu-s-roztrousenou-sklerozou\/\">\n                            ReMuS \u2013 \u010desk\u00fd celost\u00e1tn\u00ed registr pacient\u016f s roztrou\u0161enou skler\u00f3zou                    <\/a>\n                <\/h2>\n                                                        \n                                                                                                                                                                            <p>\u010cl\u00e1nek doc. Dany Hor\u00e1kov\u00e9 publikovan\u00fd v \u010dasopisu Multiple Sclerosis News nab\u00edz\u00ed podrobn\u00fd pohled na vznik a v\u00fdvoj \u010desk\u00e9ho celost\u00e1tn\u00edho registru pacient\u016f s roztrou\u0161enou skler\u00f3zou, ReMuS, od jeho zalo\u017een\u00ed v roce 2013. \u010cten\u00e1\u0159 zde nalezne informace o struktu\u0159e registru, procesu sb\u011bru dat, a&#8230;<\/p>\n                                                                                                                                                                <div class=\"post-meta-list\">\n                                                                                                <span class=\"meta-date\">\n\n                                <i aria-hidden=\"true\" class=\"icon icon-calendar3\"><\/i>\n                                <span class=\"meta-date-text\">\n                                    15. 11. 2016                                <\/span>\n                            <\/span>\n                                                                                                                                                                                                <span class=\"post-cat\">\n\n                                \n\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/category\/publikace\/\" rel=\"category tag\">publikace<\/a>\n                            <\/span>\n                                                                                    <\/div>\n                                                                                                                            <div class=\"btn-wraper\">\n                                    \n                                                                            <a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2016\/11\/15\/remus-cesky-celostatni-registr-pacientu-s-roztrousenou-sklerozou\/\" class=\"elementskit-btn  whitespace--normal\" >\n                                                                                    P\u0159e\u010d\u00edst v\u00edce                                         <\/a>\n                                                                    <\/div>\n                                                    <\/div><!-- .elementskit-post-body END -->\n                    <\/div>\n                \n            <\/div>\t\t\t\t        <\/div>\n        \n        \n        <\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ab9d476 elementor-hidden-mobile e-flex e-con-boxed e-con e-child\" data-id=\"ab9d476\" data-element_type=\"container\" data-settings=\"{&quot;sticky&quot;:&quot;bottom&quot;,&quot;sticky_offset&quot;:100,&quot;sticky_parent&quot;:&quot;yes&quot;,&quot;animation&quot;:&quot;none&quot;,&quot;sticky_on&quot;:[&quot;desktop&quot;,&quot;tablet&quot;,&quot;mobile&quot;],&quot;sticky_effects_offset&quot;:0,&quot;sticky_anchor_link_offset&quot;:0}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7155842 elementor-hidden-mobile elementor-widget elementor-widget-heading\" data-id=\"7155842\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Archiv<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e60dc6b elementor-grid-1 elementor-grid-tablet-1 elementor-posts--thumbnail-none elementor-hidden-mobile elementor-grid-mobile-1 elementor-widget elementor-widget-posts\" data-id=\"e60dc6b\" data-element_type=\"widget\" data-settings=\"{&quot;classic_columns&quot;:&quot;1&quot;,&quot;classic_columns_tablet&quot;:&quot;1&quot;,&quot;classic_row_gap&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:0,&quot;sizes&quot;:[]},&quot;classic_columns_mobile&quot;:&quot;1&quot;,&quot;classic_row_gap_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;classic_row_gap_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"posts.classic\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-posts-container elementor-posts elementor-posts--skin-classic elementor-grid\" role=\"list\">\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-9264 post type-post status-publish format-standard has-post-thumbnail hentry category-akce category-publikace\" role=\"listitem\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2026\/05\/27\/tiskova-konference-remus-27-kvetna-2026\/\" >\n\t\t\t\tTiskov\u00e1 konference ReMuS | 27. kv\u011btna 2026\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\t27. 5. 2026\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-8977 post type-post status-publish format-standard has-post-thumbnail hentry category-publikace\" role=\"listitem\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2026\/04\/19\/pet-na-pet-ceska-petileta-data-o-kladribinu-na-aan-2026-v-chicagu\/\" >\n\t\t\t\tP\u011bt na p\u011bt: \u010desk\u00e1 p\u011btilet\u00e1 data o kladribinu na AAN 2026 v Chicagu\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\t19. 4. 2026\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-7673 post type-post status-publish format-standard has-post-thumbnail hentry category-publikace tag-medical-professionals-only\" role=\"listitem\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2025\/12\/23\/od-slunecniho-zareni-k-boji-proti-roztrousene-skleroze-vliv-hladiny-vitaminu-d-na-aktivitu-roztrousene-sklerozy\/\" >\n\t\t\t\tOd slune\u010dn\u00edho z\u00e1\u0159en\u00ed k boji proti roztrou\u0161en\u00e9 skler\u00f3ze: vliv hladiny vitam\u00ednu D na aktivitu roztrou\u0161en\u00e9 skler\u00f3zy\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\t23. 12. 2025\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-4642 post type-post status-publish format-standard hentry category-publikace\" role=\"listitem\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2025\/04\/08\/remus-v-americe-poster-na-prestiznim-neurologickem-kongresu-american-academy-of-neurology\/\" >\n\t\t\t\tReMuS v Americe \u2013 poster na presti\u017en\u00edm neurologick\u00e9m kongresu American Academy of Neurology\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\t8. 4. 2025\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-3758 post type-post status-publish format-standard has-post-thumbnail hentry category-publikace\" role=\"listitem\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2024\/09\/18\/seznamte-se-s-registrem-remus\/\" >\n\t\t\t\tSeznamte se s registrem ReMuS\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\t18. 9. 2024\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-2606 post type-post status-publish format-standard has-post-thumbnail hentry category-publikace tag-medical-professionals-only\" role=\"listitem\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2024\/06\/24\/ucinnost-kladribinu-jako-eskalacni-strategie-u-rs-v-realne-klinicke-praxi-poznatky-z-ceskeho-celostatniho-registru-remus\/\" >\n\t\t\t\t\u00da\u010dinnost kladribinu jako eskala\u010dn\u00ed strategie u RS v re\u00e1ln\u00e9 klinick\u00e9 praxi: Poznatky z \u010desk\u00e9ho celost\u00e1tn\u00edho registru ReMuS\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\t24. 6. 2024\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-2881 post type-post status-publish format-standard has-post-thumbnail hentry category-akce category-publikace\" role=\"listitem\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2024\/05\/29\/neurologove-vsichni-pacienti-musi-dostat-kvalitni-peci-tiskova-konference-registru-remus-2024\/\" >\n\t\t\t\tNeurologov\u00e9: v\u0161ichni pacienti mus\u00ed dostat kvalitn\u00ed p\u00e9\u010di | Tiskov\u00e1 konference registru ReMuS 2024\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\t29. 5. 2024\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-3693 post type-post status-publish format-standard has-post-thumbnail hentry category-publikace tag-medical-professionals-only\" role=\"listitem\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2024\/04\/01\/big-multiple-sclerosis-data-network-mezinarodni-vyzkumna-sit-registru\/\" >\n\t\t\t\tBig Multiple Sclerosis Data network: mezin\u00e1rodn\u00ed v\u00fdzkumn\u00e1 s\u00ed\u0165 registr\u016f\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\t1. 4. 2024\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-2572 post type-post status-publish format-standard has-post-thumbnail hentry category-publikace tag-medical-professionals-only\" role=\"listitem\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2023\/09\/26\/vliv-zdravotnickych-systemu-na-diagnozu-a-pouzivani-lecby-modifikujici-onemocneni-u-roztrousene-sklerozy-pohled-na-pet-evropskych-registru\/\" >\n\t\t\t\tVliv zdravotnick\u00fdch syst\u00e9m\u016f na diagn\u00f3zu a pou\u017e\u00edv\u00e1n\u00ed l\u00e9\u010dby modifikuj\u00edc\u00ed onemocn\u011bn\u00ed u roztrou\u0161en\u00e9 skler\u00f3zy: pohled na p\u011bt evropsk\u00fdch registr\u016f\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\t26. 9. 2023\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-2433 post type-post status-publish format-standard has-post-thumbnail hentry category-publikace tag-medical-professionals-only\" role=\"listitem\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2023\/06\/15\/je-kojeni-pri-rs-skodlive-nebo-ne-odpoved-na-zaklade-realnych-dat-z-ceska\/\" >\n\t\t\t\tJe kojen\u00ed p\u0159i RS \u0161kodliv\u00e9, nebo ne? Odpov\u011b\u010f na z\u00e1klad\u011b re\u00e1ln\u00fdch dat z \u010ceska\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\t15. 6. 2023\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-2677 post type-post status-publish format-standard has-post-thumbnail hentry category-publikace tag-medical-professionals-only\" role=\"listitem\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2023\/06\/12\/prekonava-pocatecni-vysoce-ucinna-lecba-u-roztrousene-sklerozy-strategii-postupne-eskalace-lecby-srovnani-pacientu-s-relabujici-remitentni-roztrousenou-sklerozou-v-ceskem-a-svedskem-narodnim-registru\/\" >\n\t\t\t\tP\u0159ekon\u00e1v\u00e1 po\u010d\u00e1te\u010dn\u00ed vysoce \u00fa\u010dinn\u00e1 l\u00e9\u010dba u roztrou\u0161en\u00e9 skler\u00f3zy strategii postupn\u00e9 eskalace l\u00e9\u010dby? Srovn\u00e1n\u00ed pacient\u016f s relabuj\u00edc\u00ed-remitentn\u00ed roztrou\u0161enou skler\u00f3zou v \u010desk\u00e9m a \u0161v\u00e9dsk\u00e9m n\u00e1rodn\u00edm registru roztrou\u0161en\u00e9 skler\u00f3zy.\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\t12. 6. 2023\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-2675 post type-post status-publish format-standard has-post-thumbnail hentry category-akce category-publikace\" role=\"listitem\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2023\/05\/25\/tiskova-konference-registru-remus-2023\/\" >\n\t\t\t\tL\u00e9\u010dba roztrou\u0161en\u00e9 skler\u00f3zy za\u017e\u00edv\u00e1 revoluci | Tiskov\u00e1 konference registru ReMuS 2023\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\t25. 5. 2023\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-2680 post type-post status-publish format-standard has-post-thumbnail hentry category-publikace tag-medical-professionals-only\" role=\"listitem\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2023\/03\/28\/cesky-narodni-registr-roztrousene-sklerozy-remus-trendy-dat-u-pacientu-s-roztrousenou-sklerozou-u-nichz-byla-v-letech-2013-2021-zahajena-prvni-chorobu-modifikujici-lecba\/\" >\n\t\t\t\t\u010cesk\u00fd n\u00e1rodn\u00ed registr roztrou\u0161en\u00e9 skler\u00f3zy ReMuS: Trendy dat u pacient\u016f s roztrou\u0161enou skler\u00f3zou, u nich\u017e byla v letech 2013-2021 zah\u00e1jena prvn\u00ed chorobu modifikuj\u00edc\u00ed l\u00e9\u010dba.\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\t28. 3. 2023\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-2686 post type-post status-publish format-standard has-post-thumbnail hentry category-publikace tag-medical-professionals-only\" role=\"listitem\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2023\/02\/16\/podil-a-charakteristiky-sekundarni-progresivni-roztrousene-sklerozy-v-peti-evropskych-registrech-s-vyuzitim-objektivnich-klasifikatoru\/\" >\n\t\t\t\tPod\u00edl a charakteristiky sekund\u00e1rn\u00ed progresivn\u00ed roztrou\u0161en\u00e9 skler\u00f3zy v p\u011bti evropsk\u00fdch registrech s vyu\u017eit\u00edm objektivn\u00edch klasifik\u00e1tor\u016f\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\t16. 2. 2023\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-2702 post type-post status-publish format-standard has-post-thumbnail hentry category-publikace tag-medical-professionals-only\" role=\"listitem\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2022\/07\/02\/byt-ci-nebyt-ockovan-riziko-relapsu-rs-nebo-nmosd-po-ockovani-a-infekci-covid-19\/\" >\n\t\t\t\tB\u00fdt \u010di neb\u00fdt o\u010dkov\u00e1n: Riziko relapsu RS nebo NMOSD po o\u010dkov\u00e1n\u00ed a infekci COVID-19\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\t2. 7. 2022\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-2705 post type-post status-publish format-standard has-post-thumbnail hentry category-publikace tag-medical-professionals-only\" role=\"listitem\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2022\/04\/18\/analyza-skupiny-detskych-pacientu-s-relabujici-roztrousenou-sklerozou-udaje-z-ceskeho-narodniho-registru\/\" >\n\t\t\t\tAnal\u00fdza skupiny d\u011btsk\u00fdch pacient\u016f s relabuj\u00edc\u00ed roztrou\u0161enou skler\u00f3zou: \u00dadaje z \u010desk\u00e9ho n\u00e1rodn\u00edho registru\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\t18. 4. 2022\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-2708 post type-post status-publish format-standard has-post-thumbnail hentry category-publikace tag-medical-professionals-only\" role=\"listitem\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2021\/11\/28\/je-tehotenstvi-u-pacientek-s-rs-bezpecne-a-jaky-ma-vliv-na-prubeh-rs-realne-poznatky-z-1-533-tehotenstvi-v-ceske-republice\/\" >\n\t\t\t\tJe t\u011bhotenstv\u00ed u pacientek s RS bezpe\u010dn\u00e9 a jak\u00fd m\u00e1 vliv na pr\u016fb\u011bh RS? Re\u00e1ln\u00e9 poznatky z 1 533 t\u011bhotenstv\u00ed v \u010cesk\u00e9 republice\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\t28. 11. 2021\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-2711 post type-post status-publish format-standard has-post-thumbnail hentry category-publikace tag-medical-professionals-only\" role=\"listitem\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2021\/06\/24\/roztrousena-skleroza-neuromyelitis-optica-a-covid-19-pandemicky-rok-v-cesku\/\" >\n\t\t\t\tRoztrou\u0161en\u00e1 skler\u00f3za, neuromyelitis optica a COVID-19: Pandemick\u00fd rok v \u010cesku\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\t24. 6. 2021\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-52 post type-post status-publish format-standard has-post-thumbnail hentry category-akce category-publikace\" role=\"listitem\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2021\/05\/25\/covid-19-a-roztrousena-skleroza-pod-drobnohledem\/\" >\n\t\t\t\tCovid-19 a roztrou\u0161en\u00e1 skler\u00f3za pod drobnohledem | Tiskov\u00e1 konference registru ReMuS 2021\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\t25. 5. 2021\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-2713 post type-post status-publish format-standard has-post-thumbnail hentry category-publikace tag-medical-professionals-only\" role=\"listitem\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2021\/03\/17\/roztrousena-skleroza-neuromyelitis-optica-a-covid-19-pandemicky-rok-v-ceskuzmena-lecby-a-preruseni-lecby-v-prubehu-20-let-ve-skupine-registru-big-multiple-sclerosis-data-network\/\" >\n\t\t\t\tZm\u011bna l\u00e9\u010dby a p\u0159eru\u0161en\u00ed l\u00e9\u010dby v pr\u016fb\u011bhu 20 let ve skupin\u011b registr\u016f Big Multiple Sclerosis Data Network\u200b\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\t17. 3. 2021\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-2717 post type-post status-publish format-standard has-post-thumbnail hentry category-publikace tag-medical-professionals-only\" role=\"listitem\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2021\/01\/12\/srovnani-terapie-u-pacientu-s-rs-po-prvni-demyelinizacni-prihode-v-realne-klinicke-praxi-v-ceske-republice-udaje-z-narodniho-registru-remus\/\" >\n\t\t\t\tSrovn\u00e1n\u00ed terapie u pacient\u016f s RS po prvn\u00ed demyeliniza\u010dn\u00ed p\u0159\u00edhod\u011b v re\u00e1ln\u00e9 klinick\u00e9 praxi v \u010cesk\u00e9 republice: \u00dadaje z n\u00e1rodn\u00edho registru ReMuS\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\t12. 1. 2021\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-2721 post type-post status-publish format-standard has-post-thumbnail hentry category-publikace tag-medical-professionals-only\" role=\"listitem\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2020\/10\/15\/jaka-data-nabizi-celostatni-registr-pacientu-s-roztrousenou-sklerozou-remus\/\" >\n\t\t\t\tJak\u00e1 data nab\u00edz\u00ed celost\u00e1tn\u00ed registr pacient\u016f s roztrou\u0161enou skler\u00f3zou ReMuS?\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\t15. 10. 2020\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-2724 post type-post status-publish format-standard has-post-thumbnail hentry category-publikace tag-medical-professionals-only\" role=\"listitem\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2019\/09\/21\/registr-pacientu-s-roztrousenou-sklerozou-remus-vyznam-dat-u-chronickych-onemocneni\/\" >\n\t\t\t\tRegistr pacient\u016f s roztrou\u0161enou skler\u00f3zou ReMuS \u2013 v\u00fdznam dat u chronick\u00fdch onemocn\u011bn\u00ed\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\t21. 9. 2019\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-2727 post type-post status-publish format-standard has-post-thumbnail hentry category-publikace tag-medical-professionals-only\" role=\"listitem\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2019\/08\/03\/zahajeni-prvni-chorobu-modifikujici-lecby-u-pacientu-s-roztrousenou-sklerozou-v-ceske-republice-v-letech-2013-2016-udaje-z-narodniho-registru-remus\/\" >\n\t\t\t\tZah\u00e1jen\u00ed prvn\u00ed chorobu modifikuj\u00edc\u00ed l\u00e9\u010dby u pacient\u016f s roztrou\u0161enou skler\u00f3zou v \u010cesk\u00e9 republice v letech 2013-2016: \u00dadaje z n\u00e1rodn\u00edho registru ReMuS\u200b\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\t3. 8. 2019\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-2734 post type-post status-publish format-standard has-post-thumbnail hentry category-publikace tag-medical-professionals-only\" role=\"listitem\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2018\/12\/10\/jaka-data-nabizi-celostatni-registr-pacientu-s-roztrousenou-sklerozou-remus-2\/\" >\n\t\t\t\tKam jsme se posunuli za p\u011bt let existence registru ReMuS\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\t10. 12. 2018\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-2730 post type-post status-publish format-standard has-post-thumbnail hentry category-publikace tag-medical-professionals-only\" role=\"listitem\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2018\/10\/04\/registry-roztrousene-sklerozy-v-evrope-aktualizovany-prehled\/\" >\n\t\t\t\tRegistry roztrou\u0161en\u00e9 skler\u00f3zy v Evrop\u011b &#8211; Aktualizovan\u00fd p\u0159ehled\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\t4. 10. 2018\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-2736 post type-post status-publish format-standard has-post-thumbnail hentry category-publikace tag-medical-professionals-only\" role=\"listitem\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2018\/06\/07\/srovnani-ucinnosti-subkutanne-podavaneho-interferonu-%ce%b2-1a-44-%ce%bcg-dimetyl-fumaratu-a-fingolimodu-v-realne-klinicke-praxi-multicentricka-observacni-studie\/\" >\n\t\t\t\tSrovn\u00e1n\u00ed \u00fa\u010dinnosti subkut\u00e1nn\u011b pod\u00e1van\u00e9ho interferonu \u03b2-1a 44 \u03bcg, dimetyl fumar\u00e1tu a fingolimodu v re\u00e1ln\u00e9 klinick\u00e9 praxi \u2013 multicentrick\u00e1 observa\u010dn\u00ed studie\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\t7. 6. 2018\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-2739 post type-post status-publish format-standard has-post-thumbnail hentry category-publikace tag-medical-professionals-only\" role=\"listitem\">\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.multiplesclerosis.cz\/en\/2016\/11\/15\/remus-cesky-celostatni-registr-pacientu-s-roztrousenou-sklerozou\/\" >\n\t\t\t\tReMuS \u2013 \u010desk\u00fd celost\u00e1tn\u00ed registr pacient\u016f s roztrou\u0161enou skler\u00f3zou\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__meta-data\">\n\t\t\t\t\t<span class=\"elementor-post-date\">\n\t\t\t15. 11. 2016\t\t<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<\/div>\n\t\t\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div id=\"e-n-tab-content-1545561062\" role=\"tabpanel\" aria-labelledby=\"e-n-tab-title-1545561062\" data-tab-index=\"2\" style=\"--n-tabs-title-order: 2;\" class=\" elementor-element elementor-element-5616a05 e-con-full e-flex e-con e-child\" data-id=\"5616a05\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-91fc61e e-flex e-con-boxed e-con e-child\" data-id=\"91fc61e\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-8f2b6cf elementor-widget elementor-widget-shortcode\" data-id=\"8f2b6cf\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"shortcode.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-shortcode\"><style id=\"ms-pv-styles\">\n\/* \u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\n * ReMuS Poster Viewer \u2014 Styles (v3)\n * \u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550 *\/\n\n.ms-poster-viewer {\n  --ms-pv-accent: #20a2dc;\n  --ms-pv-accent-weak: rgba(32, 162, 220, .35);\n  --ms-pv-bg-glass: rgba(62, 66, 74, .82);\n  --ms-pv-thumb-h: 110px;\n  --ms-pv-stage-h: 560px;\n\n  position: relative;\n  font-family: system-ui, -apple-system, \"Segoe UI\", Roboto, Helvetica, Arial, sans-serif;\n  color: #fff;\n  background: transparent;\n  overscroll-behavior: contain;\n}\n\n.ms-poster-viewer *,\n.ms-poster-viewer *::before,\n.ms-poster-viewer *::after {\n  box-sizing: border-box;\n}\n\n.ms-poster-viewer > script.ms-pv-config {\n  display: none !important;\n}\n\n\/* \u2500\u2500 Toolbar \u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500 *\/\n.ms-poster-viewer .ms-pv-toolbar {\n  position: absolute;\n  right: 10px;\n  top: 10px;\n  z-index: 10;\n  display: flex;\n  flex-direction: column;\n  gap: 8px;\n  transition: opacity .4s ease;\n}\n\n.ms-poster-viewer .ms-pv-btn {\n  appearance: none;\n  display: inline-flex;\n  align-items: center;\n  justify-content: center;\n  min-width: 44px;\n  height: 44px;\n  padding: 0 12px;\n  border: 1px solid rgba(0, 0, 0, .08);\n  border-radius: 14px;\n  background: var(--ms-pv-bg-glass);\n  color: #fff;\n  font: 600 18px\/1 system-ui, -apple-system, \"Segoe UI\", Roboto, sans-serif;\n  cursor: pointer;\n  text-decoration: none;\n  box-shadow: 0 6px 20px rgba(0, 0, 0, .18);\n  backdrop-filter: blur(6px);\n  -webkit-backdrop-filter: blur(6px);\n  transition: transform .12s ease, opacity .2s ease, background .15s ease;\n  touch-action: manipulation;\n  user-select: none;\n}\n\n.ms-poster-viewer .ms-pv-btn:hover { transform: translateY(-1px); }\n.ms-poster-viewer .ms-pv-btn:active { transform: translateY(0); }\n\n\/* Lock shape across all states; themes often strip these on hover *\/\n.ms-poster-viewer .ms-pv-btn,\n.ms-poster-viewer .ms-pv-btn:hover,\n.ms-poster-viewer .ms-pv-btn:focus,\n.ms-poster-viewer .ms-pv-btn:focus-visible,\n.ms-poster-viewer .ms-pv-btn:active,\n.ms-poster-viewer .ms-pv-btn:visited {\n  border-radius: 14px !important;\n  outline: none !important;\n}\n.ms-poster-viewer .ms-pv-btn:focus:not(:focus-visible) {\n  background: var(--ms-pv-bg-glass);\n}\n.ms-poster-viewer .ms-pv-btn:focus-visible {\n  box-shadow: 0 6px 20px rgba(0, 0, 0, .18),\n              0 0 0 3px var(--ms-pv-accent-weak);\n}\n.ms-poster-viewer .ms-pv-btn[aria-disabled=\"true\"] {\n  opacity: .25;\n  pointer-events: none;\n}\n\n.ms-poster-viewer.is-ui-faded .ms-pv-toolbar,\n.ms-poster-viewer.is-ui-faded .ms-pv-nav {\n  opacity: .08;\n}\n\n\/* Fullscreen icon toggle *\/\n.ms-poster-viewer .ms-pv-icon {\n  display: inline-block;\n  width: 18px;\n  height: 18px;\n  vertical-align: middle;\n  pointer-events: none;\n}\n.ms-poster-viewer .ms-pv-icon-collapse { display: none; }\n.ms-poster-viewer.is-fs-active .ms-pv-icon-expand { display: none; }\n.ms-poster-viewer.is-fs-active .ms-pv-icon-collapse { display: inline-block; }\n\n\/* \u2500\u2500 Thumbnails \u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500 *\/\n.ms-poster-viewer .ms-pv-thumbs-wrap {\n  position: relative;\n  margin: 0 0 12px 0;\n}\n\n.ms-poster-viewer .ms-pv-thumbs {\n  display: flex;\n  flex-wrap: nowrap;\n  gap: 10px;\n  justify-content: safe center;\n  margin: 0;\n  padding: 2px 4px;\n  overflow-x: auto;\n  scroll-snap-type: x proximity;\n  scrollbar-width: thin;\n}\n\n.ms-poster-viewer .ms-pv-thumb {\n  appearance: none;\n  padding: 0;\n  border: 0;\n  background: transparent;\n  cursor: pointer;\n  border-radius: 10px;\n  line-height: 0;\n  scroll-snap-align: start;\n  flex: 0 0 auto;\n}\n.ms-poster-viewer .ms-pv-thumb,\n.ms-poster-viewer .ms-pv-thumb:hover,\n.ms-poster-viewer .ms-pv-thumb:focus,\n.ms-poster-viewer .ms-pv-thumb:focus-visible,\n.ms-poster-viewer .ms-pv-thumb:active {\n  background: transparent !important;\n  box-shadow: none !important;\n  border: 0 !important;\n  outline: none !important;\n}\n\n.ms-poster-viewer .ms-pv-thumb canvas,\n.ms-poster-viewer .ms-pv-thumb .ms-pv-thumb-image,\n.ms-poster-viewer .ms-pv-thumb .ms-pv-thumb-skeleton {\n  display: block;\n  height: var(--ms-pv-thumb-h);\n  width: auto;\n  max-width: 200px;\n  object-fit: contain;\n  border-radius: 10px;\n  border: 4px solid var(--ms-pv-accent-weak);\n  background: rgba(0, 0, 0, .04);\n  transition: border-color .15s ease;\n}\n\n.ms-poster-viewer .ms-pv-thumb .ms-pv-thumb-skeleton {\n  width: calc(var(--ms-pv-thumb-h) * 0.7);\n  background: linear-gradient(90deg,\n    rgba(128, 128, 128, .12) 0%,\n    rgba(128, 128, 128, .22) 50%,\n    rgba(128, 128, 128, .12) 100%);\n  background-size: 200% 100%;\n  animation: ms-pv-shimmer 1.4s ease-in-out infinite;\n}\n\n@keyframes ms-pv-shimmer {\n  0%   { background-position: 200% 0; }\n  100% { background-position: -200% 0; }\n}\n\n.ms-poster-viewer .ms-pv-thumb:hover canvas,\n.ms-poster-viewer .ms-pv-thumb:hover .ms-pv-thumb-image,\n.ms-poster-viewer .ms-pv-thumb:focus-visible canvas,\n.ms-poster-viewer .ms-pv-thumb:focus-visible .ms-pv-thumb-image {\n  border-color: var(--ms-pv-accent);\n}\n\n.ms-poster-viewer .ms-pv-thumb[aria-current=\"true\"] canvas,\n.ms-poster-viewer .ms-pv-thumb[aria-current=\"true\"] .ms-pv-thumb-image {\n  border-color: var(--ms-pv-accent);\n  box-shadow: 0 0 0 2px var(--ms-pv-accent-weak) inset;\n}\n\n\/* Scroll indicators *\/\n.ms-poster-viewer .ms-pv-thumbs-wrap::before,\n.ms-poster-viewer .ms-pv-thumbs-wrap::after {\n  position: absolute;\n  top: 0;\n  bottom: 0;\n  width: 36px;\n  pointer-events: none;\n  z-index: 5;\n  display: flex;\n  align-items: center;\n  font-size: 24px;\n  font-weight: 700;\n  color: rgba(0, 0, 0, .45);\n  opacity: 0;\n  transition: opacity .25s ease;\n}\n.ms-poster-viewer .ms-pv-thumbs-wrap::before {\n  content: '\u2039';\n  left: 0;\n  justify-content: flex-start;\n  padding-left: 6px;\n  background: linear-gradient(to right, rgba(0, 0, 0, .08), rgba(0, 0, 0, 0));\n  border-radius: 10px 0 0 10px;\n}\n.ms-poster-viewer .ms-pv-thumbs-wrap::after {\n  content: '\u203a';\n  right: 0;\n  justify-content: flex-end;\n  padding-right: 6px;\n  background: linear-gradient(to left, rgba(0, 0, 0, .08), rgba(0, 0, 0, 0));\n  border-radius: 0 10px 10px 0;\n}\n.ms-poster-viewer .ms-pv-thumbs-wrap.has-scroll-left::before { opacity: 1; }\n.ms-poster-viewer .ms-pv-thumbs-wrap.has-scroll-right::after { opacity: 1; }\n\n\/* \u2500\u2500 Stage \u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500 *\/\n.ms-poster-viewer .ms-pv-stage {\n  position: relative;\n  width: 100%;\n  min-height: 220px;\n  border-radius: 14px;\n  overflow: hidden;\n}\n\n.ms-poster-viewer .ms-pv-canvas-wrap {\n  position: relative;\n  width: 100%;\n  height: var(--ms-pv-stage-h);\n  overflow: hidden;\n  border-radius: 14px;\n  cursor: grab;\n  touch-action: none;\n  user-select: none;\n  -webkit-user-select: none;\n  -webkit-touch-callout: none;\n  overscroll-behavior: contain;\n}\n.ms-poster-viewer .ms-pv-canvas-wrap[data-fit=\"true\"] {\n  touch-action: pan-y;\n  cursor: auto;\n}\n.ms-poster-viewer .ms-pv-canvas-wrap:active { cursor: grabbing; }\n.ms-poster-viewer .ms-pv-canvas-wrap[data-fit=\"true\"]:active { cursor: auto; }\n\n\/* Canvas element (used in both PDF and JPEG modes).\n   Pan\/zoom transforms apply via transform: translate+scale. *\/\n.ms-poster-viewer .ms-pv-canvas {\n  position: absolute;\n  left: 0;\n  top: 0;\n  transform-origin: 0 0;\n  will-change: transform;\n  visibility: hidden;\n  -webkit-user-drag: none;\n  image-rendering: auto;\n}\n\n\/* Mobile card \u2014 shown in place of inline poster on the JPEG path.\n   Thumbnail + title + \"Open PDF\" button. iOS's native PDF viewer\n   handles actual poster viewing when the user taps the button. *\/\n.ms-poster-viewer .ms-pv-fallback {\n  position: absolute;\n  inset: 0;\n  display: flex;\n  flex-direction: column;\n  align-items: center;\n  justify-content: center;\n  padding: 1.5rem 1rem;\n  text-align: center;\n  color: #333;\n  background: rgba(255, 255, 255, .92);\n  border-radius: 14px;\n  gap: 0.75rem;\n}\n.ms-poster-viewer .ms-pv-fallback-thumb {\n  max-width: 60%;\n  max-height: 60%;\n  object-fit: contain;\n  border-radius: 8px;\n  box-shadow: 0 4px 16px rgba(0, 0, 0, .12);\n}\n.ms-poster-viewer .ms-pv-fallback-title {\n  font-size: 1rem;\n  font-weight: 600;\n  color: #222;\n  max-width: 90%;\n}\n.ms-poster-viewer .ms-pv-fallback-msg {\n  font-size: 0.9rem;\n  font-weight: 400;\n  color: #666;\n  margin: 0;\n}\n.ms-poster-viewer .ms-pv-fallback-link {\n  display: inline-flex;\n  align-items: center;\n  gap: 0.5rem;\n  padding: 0.75rem 1.5rem;\n  background: var(--ms-pv-accent);\n  color: #fff;\n  border-radius: 12px;\n  font-weight: 600;\n  text-decoration: none;\n  transition: background .15s ease;\n}\n.ms-poster-viewer .ms-pv-fallback-link:hover,\n.ms-poster-viewer .ms-pv-fallback-link:focus-visible {\n  background: #1685b5;\n  color: #fff;\n  text-decoration: none;\n}\n\n\/* On the mobile JPEG path there's nothing to zoom, pan, or make\n   fullscreen, so hide those toolbar buttons. Leaves only the\n   download arrow visible in the toolbar. Play\/pause also hidden\n   since mobile autoplay through static cards would be pointless. *\/\n.ms-poster-viewer.is-mode-jpeg [data-act=\"zoom-in\"],\n.ms-poster-viewer.is-mode-jpeg [data-act=\"zoom-out\"],\n.ms-poster-viewer.is-mode-jpeg [data-act=\"reset\"],\n.ms-poster-viewer.is-mode-jpeg [data-act=\"fullscreen\"],\n.ms-poster-viewer.is-mode-jpeg [data-act=\"toggle-play\"] {\n  display: none;\n}\n\n\/* Mobile-mode stage can shrink since there's no image to show.\n   Still give it height so the card has room to breathe. *\/\n.ms-poster-viewer.is-mode-jpeg {\n  --ms-pv-stage-h: 380px;\n}\n.ms-poster-viewer.is-mode-jpeg .ms-pv-canvas-wrap {\n  cursor: auto;\n  touch-action: auto;\n}\n\n\/* Loading overlay *\/\n.ms-poster-viewer .ms-pv-loading {\n  position: absolute;\n  inset: 0;\n  display: flex;\n  align-items: center;\n  justify-content: center;\n  pointer-events: none;\n  opacity: 0;\n  transition: opacity .2s ease;\n  z-index: 7;\n}\n.ms-poster-viewer .ms-pv-loading.is-visible { opacity: 1; }\n\n.ms-poster-viewer .ms-pv-spinner {\n  width: 44px;\n  height: 44px;\n  border-radius: 50%;\n  border: 3px solid rgba(128, 128, 128, .25);\n  border-top-color: var(--ms-pv-accent);\n  animation: ms-pv-spin .9s linear infinite;\n}\n@keyframes ms-pv-spin { to { transform: rotate(360deg); } }\n\n\/* Nav arrows \u2014 same glass styling as toolbar *\/\n.ms-poster-viewer .ms-pv-nav {\n  position: absolute;\n  top: 50%;\n  transform: translateY(-50%);\n  z-index: 6;\n  appearance: none;\n  width: 52px;\n  height: 52px;\n  border: 1px solid rgba(0, 0, 0, .08);\n  border-radius: 16px;\n  background: var(--ms-pv-bg-glass);\n  color: #fff;\n  font: 700 28px\/1 system-ui, sans-serif;\n  cursor: pointer;\n  backdrop-filter: blur(6px);\n  -webkit-backdrop-filter: blur(6px);\n  display: inline-flex;\n  align-items: center;\n  justify-content: center;\n  box-shadow: 0 6px 20px rgba(0, 0, 0, .18);\n  transition: opacity .4s ease, background .15s ease, transform .12s ease;\n  touch-action: manipulation;\n  user-select: none;\n  padding: 0;\n}\n.ms-poster-viewer .ms-pv-nav:hover {\n  background: rgba(32, 162, 220, .55);\n  transform: translateY(calc(-50% - 1px));\n}\n.ms-poster-viewer .ms-pv-nav:active { transform: translateY(-50%); }\n.ms-poster-viewer .ms-pv-nav,\n.ms-poster-viewer .ms-pv-nav:hover,\n.ms-poster-viewer .ms-pv-nav:focus,\n.ms-poster-viewer .ms-pv-nav:focus-visible,\n.ms-poster-viewer .ms-pv-nav:active {\n  border-radius: 16px !important;\n  outline: none !important;\n}\n.ms-poster-viewer .ms-pv-nav:focus:not(:focus-visible) {\n  background: var(--ms-pv-bg-glass);\n}\n.ms-poster-viewer .ms-pv-nav:focus-visible {\n  box-shadow: 0 6px 20px rgba(0, 0, 0, .18),\n              0 0 0 3px var(--ms-pv-accent-weak);\n}\n.ms-poster-viewer .ms-pv-nav.ms-pv-prev { left: 10px; }\n.ms-poster-viewer .ms-pv-nav.ms-pv-next { right: 10px; }\n.ms-poster-viewer .ms-pv-nav[aria-disabled=\"true\"] {\n  opacity: .2;\n  pointer-events: none;\n}\n\n\/* Title bar *\/\n.ms-poster-viewer .ms-pv-title {\n  position: absolute;\n  left: 12px;\n  bottom: 12px;\n  z-index: 6;\n  max-width: 75%;\n  padding: 8px 12px;\n  background: rgba(0, 0, 0, .55);\n  color: #fff;\n  border-radius: 12px;\n  font: 500 14px\/1.3 system-ui, -apple-system, \"Segoe UI\", Roboto, sans-serif;\n  pointer-events: none;\n  backdrop-filter: blur(4px);\n  -webkit-backdrop-filter: blur(4px);\n}\n\n\/* \u2500\u2500 Fullscreen \u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500 *\/\n.ms-poster-viewer:fullscreen,\n.ms-poster-viewer.is-fs-fallback {\n  --ms-pv-stage-h: 100vh;\n  background: #0b0c0e;\n  padding: 0;\n  width: 100vw;\n  height: 100vh;\n  display: flex;\n  flex-direction: column;\n}\n.ms-poster-viewer.is-fs-fallback {\n  position: fixed;\n  inset: 0;\n  z-index: 99999;\n}\n.ms-poster-viewer:fullscreen .ms-pv-thumbs-wrap,\n.ms-poster-viewer.is-fs-fallback .ms-pv-thumbs-wrap {\n  flex: 0 0 auto;\n  padding: 10px;\n  margin: 0;\n  background: rgba(0, 0, 0, .35);\n}\n.ms-poster-viewer:fullscreen .ms-pv-stage,\n.ms-poster-viewer.is-fs-fallback .ms-pv-stage {\n  flex: 1 1 auto;\n  border-radius: 0;\n}\n.ms-poster-viewer:fullscreen .ms-pv-canvas-wrap,\n.ms-poster-viewer.is-fs-fallback .ms-pv-canvas-wrap {\n  height: 100%;\n  border-radius: 0;\n}\n\n\/* \u2500\u2500 Mobile layout \u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500 *\/\n@media (max-width: 767px) {\n  .ms-poster-viewer {\n    --ms-pv-stage-h: 62vh;\n    --ms-pv-thumb-h: 88px;\n  }\n  .ms-poster-viewer .ms-pv-toolbar {\n    position: static;\n    flex-direction: row;\n    justify-content: center;\n    flex-wrap: wrap;\n    gap: 6px;\n    margin: 8px 0 6px;\n  }\n  .ms-poster-viewer .ms-pv-btn {\n    min-width: 38px;\n    height: 38px;\n    padding: 0 10px;\n    border-radius: 11px;\n    font-size: 15px;\n  }\n  .ms-poster-viewer .ms-pv-nav {\n    width: 38px;\n    height: 38px;\n    font-size: 20px;\n    border-radius: 11px !important;\n  }\n  .ms-poster-viewer .ms-pv-title {\n    left: 8px;\n    bottom: 8px;\n    font-size: 12px;\n    padding: 6px 10px;\n    max-width: calc(100% - 100px);\n  }\n  .ms-poster-viewer .ms-pv-thumbs { gap: 6px; }\n  .ms-poster-viewer .ms-pv-fallback-msg { font-size: 1rem; }\n}\n\n@media (max-width: 400px) {\n  .ms-poster-viewer .ms-pv-nav { display: none; }\n}\n\n@media (prefers-reduced-motion: reduce) {\n  .ms-poster-viewer * {\n    transition-duration: 0.01ms !important;\n    animation-duration: 0.01ms !important;\n  }\n}<\/style>\n<script id=\"ms-pv-runtime\">\n\/* \u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\n * ReMuS Poster Viewer \u2014 v3 runtime\n *\n * Two rendering paths:\n *   - PDF path (desktop): PDF.js canvas render, pan\/zoom, re-render\n *     at higher DPI after zoom change for crispness\n *   - JPEG path (mobile): Static <img> from shortcode field 4, same\n *     pan\/zoom code operating on the img element\n *\n * Path selection is driven by device-type detection matched against\n * the PHP-side routing config. See detectDeviceType() and init().\n *\n * Deep-link contract preserved:\n *   window.remusPosterSwiper.slideToLoop(n)\n *   CustomEvent \"remus:poster-ready\"  { count }\n *   CustomEvent \"remus:poster-change\" { index }\n * \u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550 *\/\n\n(() => {\n  'use strict';\n\n  \/\/ \u2500\u2500 Tunables \u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\n  const THUMB_RENDER_SCALE = 0.35;\n  const UI_FADE_MS         = 3000;\n  const ZOOM_STEP          = 1.5;\n  const ZOOM_MAX           = 10.0;   \/\/ 2\u00d7 prior limit (was 5.0)\n  const RERENDER_DEBOUNCE  = 350;\n  const DOUBLE_TAP_MS      = 280;\n  const DOUBLE_TAP_PX      = 40;\n\n  \/\/ \u2500\u2500 Internationalization \u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\n  \/\/\n  \/\/ TranslatePress doesn't reach strings that are injected by our JS\n  \/\/ runtime (fallback card, dynamic aria updates) because they don't\n  \/\/ exist in the HTML when TP scans. It also misses aria-labels on\n  \/\/ some setups. Solution: self-contained i18n with a CS\/EN map, and\n  \/\/ detect current language from <html lang> (which TranslatePress\n  \/\/ sets correctly on translated pages) or URL pattern.\n  const STRINGS = {\n    cs: {\n      zoomIn:       'P\u0159ibl\u00ed\u017eit',\n      zoomOut:      'Odd\u00e1lit',\n      reset:        'Obnovit zobrazen\u00ed',\n      fullscreen:   'Cel\u00e1 obrazovka',\n      playPause:    'P\u0159ehr\u00e1t \/ Pauza',\n      downloadPdf:  'St\u00e1hnout PDF',\n      prev:         'P\u0159edchoz\u00ed',\n      next:         'Dal\u0161\u00ed',\n      thumbsLabel:  'Postery',\n      posterImage:  'Obr\u00e1zek posteru',\n      viewerLabel:  'Prohl\u00ed\u017ee\u010d poster\u016f',\n      posterControls: 'Ovl\u00e1d\u00e1n\u00ed poster\u016f',\n      cardMsg:      'Pro pln\u00e9 rozli\u0161en\u00ed otev\u0159ete PDF.',\n      openPdf:      'Otev\u0159\u00edt PDF',\n      loadFailed:   'Prohl\u00ed\u017ee\u010d se nepoda\u0159ilo na\u010d\u00edst.',\n      couldNotLoad: 'Nelze na\u010d\u00edst: ',\n    },\n    en: {\n      zoomIn:       'Zoom in',\n      zoomOut:      'Zoom out',\n      reset:        'Reset view',\n      fullscreen:   'Fullscreen',\n      playPause:    'Play \/ Pause',\n      downloadPdf:  'Download PDF',\n      prev:         'Previous',\n      next:         'Next',\n      thumbsLabel:  'Posters',\n      posterImage:  'Poster image',\n      viewerLabel:  'Poster viewer',\n      posterControls: 'Poster controls',\n      cardMsg:      'Open the PDF for full resolution.',\n      openPdf:      'Open PDF',\n      loadFailed:   'Viewer failed to load.',\n      couldNotLoad: 'Could not load: ',\n    },\n  };\n\n  \/\/ Detect current page language. Priority:\n  \/\/   1. <html lang=\"...\"> attribute (TranslatePress sets this, most\n  \/\/      WordPress themes set it, most reliable source).\n  \/\/   2. URL pattern \/en\/ anywhere in path (TranslatePress subdirectory\n  \/\/      style: multiplesclerosis.cz\/en\/o-registru\/).\n  \/\/   3. Default to Czech.\n  \/\/ Only two languages are supported; anything else falls back to CS.\n  function detectLanguage() {\n    const htmlLang = (document.documentElement.getAttribute('lang') || '').toLowerCase();\n    if (htmlLang.startsWith('en')) return 'en';\n    if (htmlLang.startsWith('cs') || htmlLang.startsWith('cz')) return 'cs';\n    const path = location.pathname;\n    if (\/\\\/en\\\/\/.test(path) || \/\\\/en$\/.test(path)) return 'en';\n    return 'cs';\n  }\n\n  \/\/ Resolved once at module load. If TranslatePress switches language\n  \/\/ it does a full page reload, so caching this is safe.\n  const LANG = detectLanguage();\n  const T = STRINGS[LANG] || STRINGS.cs;\n\n  \/\/ \u2500\u2500 Render budget (PDF path only) \u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\n  \/\/\n  \/\/ Desktop has the memory headroom so we can be generous here.\n  \/\/ Mobile never hits this code.\n  function computeRenderBudget() {\n    const dpr = window.devicePixelRatio || 1;\n    \/\/ DPR \u00d7 2.5, capped. On a 1\u00d7 display gives 2.5\u00d7 oversample;\n    \/\/ on a 2\u00d7 display (most laptops) gives 5\u00d7 CSS pixels.\n    return Math.min(dpr * 2.5, 6.0);\n  }\n\n  function computeMaxCanvasPixels() {\n    \/\/ Desktop-only path. 64 Mpx covers 10\u00d7 zoom on a 2.5\u00d7 budget\n    \/\/ without shrinkage for typical poster dimensions.\n    return 64 * 1024 * 1024;\n  }\n\n  \/\/ \u2500\u2500 Device type detection \u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\n  \/\/\n  \/\/ Returns one of: 'ios', 'android', 'desktop', 'unknown'.\n  \/\/ The PHP side sets up routing.jpeg \/ routing.pdf arrays; init()\n  \/\/ picks the path by looking up the detected type in those arrays.\n  function detectDeviceType() {\n    const ua = navigator.userAgent || '';\n    \/\/ iPad since iPadOS 13 reports 'MacIntel' + touch support\n    const isIPad = navigator.platform === 'MacIntel' && 'ontouchend' in document;\n    if (isIPad || \/iP(ad|hone|od)\/.test(ua)) return 'ios';\n    if (\/Android\/i.test(ua)) return 'android';\n    \/\/ Rough desktop check: no touch-primary pointer, or wide viewport\n    const hasTouch = ('ontouchstart' in window) || navigator.maxTouchPoints > 0;\n    const isWide   = window.matchMedia('(min-width: 1024px)').matches;\n    if (!hasTouch || isWide) return 'desktop';\n    return 'unknown';\n  }\n\n  \/\/ \u2500\u2500 PDF.js lazy loader (loaded on PDF path only) \u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\n  let pdfJsPromise = null;\n  function loadPdfJs(scriptUrl, workerUrl) {\n    if (pdfJsPromise) return pdfJsPromise;\n    if (window.pdfjsLib?.getDocument) {\n      window.pdfjsLib.GlobalWorkerOptions.workerSrc = workerUrl;\n      pdfJsPromise = Promise.resolve(window.pdfjsLib);\n      return pdfJsPromise;\n    }\n    pdfJsPromise = import(\/* @vite-ignore *\/ scriptUrl)\n      .then((mod) => {\n        const pdfjs = mod.getDocument ? mod : (mod.default || mod);\n        if (!pdfjs.getDocument) {\n          throw new Error('PDF.js module loaded but getDocument() not found');\n        }\n        pdfjs.GlobalWorkerOptions.workerSrc = workerUrl;\n        window.pdfjsLib = pdfjs;\n        return pdfjs;\n      })\n      .catch((err) => {\n        pdfJsPromise = null;\n        throw new Error('Failed to load PDF.js: ' + err.message);\n      });\n    return pdfJsPromise;\n  }\n\n  \/\/ \u2500\u2500 Utilities \u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\n  const clamp = (v, lo, hi) => Math.max(lo, Math.min(v, hi));\n\n  \/\/ \u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\n  \/\/ PosterViewer \u2014 one instance per .ms-poster-viewer root\n  \/\/ \u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\n  class PosterViewer {\n    constructor(root) {\n      this.root = root;\n\n      const cfgEl = root.querySelector('.ms-pv-config');\n      if (!cfgEl) { console.warn('<!-- ms_poster_viewer: no valid posters configured --> no config'); return; }\n      try {\n        this.config = JSON.parse(cfgEl.textContent);\n      } catch (e) {\n        console.error('<!-- ms_poster_viewer: no valid posters configured --> config parse failed', e);\n        return;\n      }\n\n      this.posters = this.config.posters || [];\n      if (!this.posters.length) return;\n\n      \/\/ Element refs\n      this.stage        = root.querySelector('.ms-pv-stage');\n      this.canvasWrap   = root.querySelector('.ms-pv-canvas-wrap');\n      this.loadingEl    = root.querySelector('.ms-pv-loading');\n      this.titleEl      = root.querySelector('.ms-pv-title');\n      this.thumbsEl     = root.querySelector('.ms-pv-thumbs');\n      this.toolbar      = root.querySelector('.ms-pv-toolbar');\n      this.prevBtn      = root.querySelector('.ms-pv-prev');\n      this.nextBtn      = root.querySelector('.ms-pv-next');\n      this.dlLink       = root.querySelector('[data-act=\"download\"]');\n      this.playBtn      = root.querySelector('[data-act=\"toggle-play\"]');\n      this.zoomInBtn    = root.querySelector('[data-act=\"zoom-in\"]');\n      this.zoomOutBtn   = root.querySelector('[data-act=\"zoom-out\"]');\n      this.resetBtn     = root.querySelector('[data-act=\"reset\"]');\n      this.fsBtn        = root.querySelector('[data-act=\"fullscreen\"]');\n\n      \/\/ These get populated by initPdfPath() or initJpegPath()\n      this.canvas       = null;  \/\/ canvas (PDF path) or img (JPEG path)\n      this.ctx          = null;  \/\/ 2D context (PDF path only)\n\n      \/\/ Common state\n      this.currentIndex   = 0;\n      this.initialized    = false;\n      this.initializing   = false;\n      this.autoplay       = !!this.config.autoplay;\n      this.idleMs         = this.config.idleMs | 0;\n      this.idleTimer      = null;\n      this.uiFadeTimer    = null;\n      this.appliedHashOnce= false;\n      this.mode           = null; \/\/ 'pdf' or 'jpeg'\n\n      \/\/ Geometry & transform\n      this.fitScale       = 1;\n      this.userZoom       = 1;\n      this.canvasCssW     = 0;\n      this.canvasCssH     = 0;\n      this.tx             = 0;\n      this.ty             = 0;\n\n      \/\/ Input state\n      this.pointers       = new Map();\n      this.pinchBase      = null;\n      this.dragRef        = null;\n      this.postPinchUntil = 0;\n      this.lastTap        = { t: 0, x: 0, y: 0 };\n\n      \/\/ PDF-path-only state\n      this.pdfCache       = new Map();\n      this.renderBudget   = computeRenderBudget();\n      this.maxCanvasPx    = computeMaxCanvasPixels();\n      this.renderedZoom   = 1;\n      this.rerenderTimer  = null;\n      this.currentRender  = null;\n\n      \/\/ Panel\/tab context for lazy init\n      this.panel  = root.closest('[role=\"tabpanel\"], [id^=\"e-n-tab-content-\"]');\n      this.tabBtn = this.panel\n        ? document.querySelector('.e-n-tab-title[aria-controls=\"' + CSS.escape(this.panel.id) + '\"]')\n        : null;\n\n      this.setupLazyInit();\n    }\n\n    setupLazyInit() {\n      if (!this.tabBtn) { this.init(); return; }\n      if (this.tabBtn.getAttribute('aria-selected') === 'true') {\n        this.init();\n        return;\n      }\n      const mo = new MutationObserver(() => {\n        if (this.tabBtn.getAttribute('aria-selected') === 'true') {\n          mo.disconnect();\n          this.init();\n        }\n      });\n      mo.observe(this.tabBtn, { attributes: true, attributeFilter: ['aria-selected', 'class'] });\n\n      \/\/ When tab is reactivated later, refit + maybe resume autoplay\n      const visMo = new MutationObserver(() => {\n        if (!this.initialized) return;\n        if (this.isPanelActive()) {\n          requestAnimationFrame(() => {\n            this.refit();\n            if (this.autoplay) this.scheduleAutoAdvance();\n          });\n        } else {\n          this.stopAutoAdvance();\n        }\n      });\n      visMo.observe(this.tabBtn, { attributes: true, attributeFilter: ['aria-selected'] });\n    }\n\n    isPanelActive() {\n      if (this.tabBtn) return this.tabBtn.getAttribute('aria-selected') === 'true';\n      if (!this.panel) return true;\n      if (this.panel.hasAttribute('hidden')) return false;\n      if (this.panel.getAttribute('aria-hidden') === 'true') return false;\n      return !!this.panel.offsetParent;\n    }\n\n    \/\/ \u2500\u2500 Path selection + init \u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\n    async init() {\n      if (this.initialized || this.initializing) return;\n      this.initializing = true;\n\n      \/\/ Pick path from device type \u2229 routing table\n      const deviceType = detectDeviceType();\n      const routing = this.config.routing || { jpeg: ['ios', 'android'], pdf: ['desktop'], unknown_path: 'jpeg' };\n      let path;\n      if (routing.jpeg.indexOf(deviceType) !== -1) path = 'jpeg';\n      else if (routing.pdf.indexOf(deviceType) !== -1) path = 'pdf';\n      else path = routing.unknown_path || 'jpeg';\n\n      this.mode = path;\n      this.root.classList.add('is-mode-' + path);\n      this.root.dataset.deviceType = deviceType;\n\n      if (path === 'jpeg') {\n        await this.initJpegPath();\n      } else {\n        await this.initPdfPath();\n      }\n\n      this.initialized  = true;\n      this.initializing = false;\n    }\n\n    \/\/ \u2500\u2500 Shared init pieces \u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\n    setAccentFromTab() {\n      try {\n        const heading = document.querySelector('.e-n-tabs-heading');\n        const active  = heading?.querySelector('.e-n-tab-title[aria-selected=\"true\"]')\n                     || heading?.querySelector('.e-n-tab-title');\n        if (!active) return;\n        const color = getComputedStyle(active).color;\n        this.root.style.setProperty('--ms-pv-accent', color);\n        const m = color.match(\/rgba?\\((\\d+),\\s*(\\d+),\\s*(\\d+)\/i);\n        if (m) {\n          this.root.style.setProperty('--ms-pv-accent-weak',\n            `rgba(${m[1]},${m[2]},${m[3]},.35)`);\n        }\n      } catch (e) { \/* non-fatal *\/ }\n    }\n\n    \/\/ Patches all static labels in the viewer's DOM to match the\n    \/\/ detected language. Runs once per init, before any user-facing\n    \/\/ text is visible. Idempotent \u2014 safe to call multiple times.\n    applyI18n() {\n      \/\/ Root aria-label\n      this.root.setAttribute('aria-label', T.viewerLabel);\n      \/\/ Toolbar group aria-label\n      if (this.toolbar) this.toolbar.setAttribute('aria-label', T.posterControls);\n      \/\/ Individual toolbar buttons\n      const setBtn = (sel, txt) => {\n        const el = this.root.querySelector(sel);\n        if (!el) return;\n        el.setAttribute('aria-label', txt);\n        el.setAttribute('title', txt);\n      };\n      setBtn('[data-act=\"zoom-in\"]',     T.zoomIn);\n      setBtn('[data-act=\"zoom-out\"]',    T.zoomOut);\n      setBtn('[data-act=\"reset\"]',       T.reset);\n      setBtn('[data-act=\"fullscreen\"]',  T.fullscreen);\n      setBtn('[data-act=\"toggle-play\"]', T.playPause);\n      setBtn('[data-act=\"download\"]',    T.downloadPdf);\n      setBtn('.ms-pv-prev',              T.prev);\n      setBtn('.ms-pv-next',              T.next);\n      \/\/ Thumbnails container\n      if (this.thumbsEl) this.thumbsEl.setAttribute('aria-label', T.thumbsLabel);\n    }\n\n    \/\/ \u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\n    \/\/ PDF path (desktop)\n    \/\/ \u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\n    async initPdfPath() {\n      try {\n        await loadPdfJs(this.config.pdfJsUrl, this.config.workerUrl);\n      } catch (err) {\n        console.error('<!-- ms_poster_viewer: no valid posters configured -->', err);\n        this.showLoading(false);\n        this.titleEl.textContent = T.loadFailed;\n        return;\n      }\n\n      \/\/ Insert canvas into the stage\n      const canvas = document.createElement('canvas');\n      canvas.className = 'ms-pv-canvas';\n      canvas.setAttribute('aria-label', T.posterImage);\n      this.canvasWrap.insertBefore(canvas, this.loadingEl);\n      this.canvas = canvas;\n      this.ctx    = canvas.getContext('2d');\n\n      this.setAccentFromTab();\n      this.applyI18n();\n      this.buildThumbPlaceholders();\n      this.wireControls();\n      this.wirePointerHandlers();\n      this.wireKeyboard();\n      this.wireResize();\n      this.wireThumbScrollIndicator();\n\n      if (this.config.deepLink) this.exposeDeepLinkShim();\n\n      await this.goTo(0, { emit: false });\n\n      if (this.config.deepLink) {\n        document.dispatchEvent(new CustomEvent('remus:poster-ready', {\n          detail: { count: this.posters.length }\n        }));\n      }\n\n      this.applyHashOnce();\n\n      const schedule = window.requestIdleCallback || (cb => setTimeout(cb, 400));\n      schedule(() => this.renderThumbnails());\n\n      if (this.autoplay) this.scheduleAutoAdvance();\n      this.showUI();\n    }\n\n    async loadPdf(index) {\n      if (this.pdfCache.has(index)) return this.pdfCache.get(index);\n      const poster = this.posters[index];\n      if (!poster) throw new Error('Poster out of range: ' + index);\n\n      const doc = await window.pdfjsLib.getDocument({\n        url: poster.url,\n        disableAutoFetch: false,\n        disableStream: false,\n      }).promise;\n\n      const page = await doc.getPage(1);\n      const vp1  = page.getViewport({ scale: 1 });\n      const entry = { doc, page, naturalW: vp1.width, naturalH: vp1.height };\n      this.pdfCache.set(index, entry);\n      return entry;\n    }\n\n    async destroyPdf(index) {\n      const entry = this.pdfCache.get(index);\n      if (!entry) return;\n      this.pdfCache.delete(index);\n      try { entry.page?.cleanup?.(); } catch (e) {}\n      try { entry.doc?.cleanup?.(); } catch (e) {}\n      try { await entry.doc?.destroy?.(); } catch (e) {}\n    }\n\n    enforceCacheLimit() {\n      const n = this.posters.length;\n      const keep = new Set([\n        this.currentIndex,\n        (this.currentIndex + 1) % n,\n        (this.currentIndex - 1 + n) % n,\n      ]);\n      for (const i of this.pdfCache.keys()) {\n        if (!keep.has(i)) this.destroyPdf(i);\n      }\n    }\n\n    prefetchNeighbors(center) {\n      const candidates = [center + 1, center - 1];\n      const schedule = window.requestIdleCallback || (cb => setTimeout(cb, 600));\n      schedule(() => {\n        for (const i of candidates) {\n          const idx = (i + this.posters.length) % this.posters.length;\n          if (!this.pdfCache.has(idx)) {\n            this.loadPdf(idx).catch(() => {});\n            break;\n          }\n        }\n      });\n    }\n\n    async renderCurrent({ atUserZoom = null } = {}) {\n      const { page, naturalW, naturalH } = this.pdfCache.get(this.currentIndex);\n\n      const wrapW = this.canvasWrap.clientWidth  || 1;\n      const wrapH = this.canvasWrap.clientHeight || 1;\n      this.fitScale = Math.min(wrapW \/ naturalW, wrapH \/ naturalH);\n      this.canvasCssW = naturalW * this.fitScale;\n      this.canvasCssH = naturalH * this.fitScale;\n\n      const zoomForRender = atUserZoom != null ? atUserZoom : this.userZoom;\n      let bitmapScale = this.renderBudget * zoomForRender;\n\n      let bitmapW = Math.round(this.canvasCssW * bitmapScale);\n      let bitmapH = Math.round(this.canvasCssH * bitmapScale);\n      if (bitmapW * bitmapH > this.maxCanvasPx) {\n        const shrink = Math.sqrt(this.maxCanvasPx \/ (bitmapW * bitmapH));\n        bitmapScale *= shrink;\n      }\n\n      const pdfScale = this.fitScale * bitmapScale;\n      const viewport = page.getViewport({ scale: pdfScale });\n\n      if (this.currentRender) {\n        try { this.currentRender.cancel(); } catch (e) {}\n        this.currentRender = null;\n      }\n\n      this.canvas.width  = Math.round(viewport.width);\n      this.canvas.height = Math.round(viewport.height);\n      this.canvas.style.width  = this.canvasCssW + 'px';\n      this.canvas.style.height = this.canvasCssH + 'px';\n      this.ctx.clearRect(0, 0, this.canvas.width, this.canvas.height);\n\n      const task = page.render({ canvasContext: this.ctx, viewport });\n      this.currentRender = task;\n\n      try { await task.promise; }\n      catch (err) {\n        if (err?.name === 'RenderingCancelledException') return;\n        throw err;\n      }\n\n      this.currentRender = null;\n      this.renderedZoom  = zoomForRender;\n      this.canvas.style.visibility = 'visible';\n    }\n\n    scheduleRerender() {\n      if (this.rerenderTimer) clearTimeout(this.rerenderTimer);\n      this.rerenderTimer = setTimeout(() => {\n        this.rerenderTimer = null;\n        const ratio = this.userZoom \/ this.renderedZoom;\n        if (ratio > 1.15 && this.userZoom > 1.01) {\n          this.renderCurrent({ atUserZoom: this.userZoom })\n            .then(() => this.applyTransform())\n            .catch(() => {});\n        }\n      }, RERENDER_DEBOUNCE);\n    }\n\n    async goToPdf(index, { emit = true } = {}) {\n      const n = this.posters.length;\n      index = ((index % n) + n) % n;\n\n      this.currentIndex = index;\n      this.showLoading(true);\n      this.titleEl.textContent = this.posters[index].title;\n      this.updateDownloadLink();\n      this.highlightThumb(index);\n\n      try {\n        await this.loadPdf(index);\n        this.userZoom = 1;\n        await this.renderCurrent({ atUserZoom: 1 });\n        this.resetView();\n      } catch (err) {\n        console.error('<!-- ms_poster_viewer: no valid posters configured --> render failed:', err);\n        this.titleEl.textContent = T.couldNotLoad + this.posters[index].title;\n      } finally {\n        this.showLoading(false);\n      }\n\n      if (emit && this.config.deepLink) {\n        document.dispatchEvent(new CustomEvent('remus:poster-change', {\n          detail: { index }\n        }));\n      }\n\n      this.prefetchNeighbors(index);\n      this.enforceCacheLimit();\n    }\n\n    async renderThumbnails() {\n      if (this.thumbsBuilt) return;\n      this.thumbsBuilt = true;\n\n      const idle = () => new Promise((resolve) => {\n        const cb = window.requestIdleCallback || ((fn) => setTimeout(fn, 50));\n        cb(resolve, { timeout: 1000 });\n      });\n\n      for (let i = 0; i < this.posters.length; i++) {\n        const btn = this.thumbsEl.querySelector('.ms-pv-thumb[data-index=\"' + i + '\"]');\n        if (!btn || btn.dataset.thumbFilled) continue;\n\n        await idle();\n\n        const wasCached = this.pdfCache.has(i);\n        try {\n          const { page } = await this.loadPdf(i);\n          const vp = page.getViewport({ scale: THUMB_RENDER_SCALE });\n          const canvas = document.createElement('canvas');\n          canvas.width  = Math.round(vp.width);\n          canvas.height = Math.round(vp.height);\n          await page.render({ canvasContext: canvas.getContext('2d'), viewport: vp }).promise;\n\n          btn.innerHTML = '';\n          btn.appendChild(canvas);\n          btn.dataset.thumbFilled = 'rendered';\n        } catch (err) {\n          console.warn('[ms_poster_viewer] thumb', i, 'failed:', err);\n        } finally {\n          const n = this.posters.length;\n          const isCurrent = i === this.currentIndex;\n          const isNext = i === (this.currentIndex + 1) % n;\n          const isPrev = i === (this.currentIndex - 1 + n) % n;\n          if (!wasCached && !isCurrent && !isNext && !isPrev) {\n            await this.destroyPdf(i);\n          }\n        }\n      }\n    }\n\n    \/\/ \u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\n    \/\/ JPEG path (mobile)\n    \/\/ \u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\n    async initJpegPath() {\n      this.setAccentFromTab();\n      this.applyI18n();\n      this.buildThumbPlaceholders();\n      this.wireControls();\n      \/\/ No wirePointerHandlers \/ wireResize \/ wireRerender needed \u2014\n      \/\/ mobile shows a static card, there's nothing to pan or zoom.\n      this.wireKeyboard();\n      this.wireThumbScrollIndicator();\n\n      if (this.config.deepLink) this.exposeDeepLinkShim();\n\n      this.goTo(0, { emit: false });\n\n      if (this.config.deepLink) {\n        document.dispatchEvent(new CustomEvent('remus:poster-ready', {\n          detail: { count: this.posters.length }\n        }));\n      }\n\n      this.applyHashOnce();\n\n      if (this.autoplay) this.scheduleAutoAdvance();\n      this.showUI();\n    }\n\n    \/\/ Mobile JPEG-path navigation \u2014 no inline rendering.\n    \/\/\n    \/\/ After much testing we concluded that reliably displaying a\n    \/\/ high-resolution poster with full pinch-zoom fidelity on iOS\n    \/\/ Safari is unsolvable without a commercial viewer SDK. Both\n    \/\/ CSS image-scaling and canvas.drawImage (even with multi-step\n    \/\/ downsampling and DPR oversampling) produced blurry output at\n    \/\/ the 15\u00d7+ downsampling ratios inherent to 6000px-source \u2192\n    \/\/ ~400px-display on phone screens.\n    \/\/\n    \/\/ Instead, on mobile we show a small preview card with the\n    \/\/ poster's thumbnail + title + \"Open PDF\" button. iOS's native\n    \/\/ PDF viewer handles the PDF perfectly (zoom, pan, search) when\n    \/\/ opened in a new tab. This is also how native apps like Mail\n    \/\/ and Files preview PDFs \u2014 the right primitive for the platform.\n    showMobileCard(poster) {\n      this.removeDisplayElement();\n      const card = document.createElement('div');\n      card.className = 'ms-pv-fallback';\n      const thumbHtml = poster.thumb\n        ? '<img decoding=\"async\" class=\"ms-pv-fallback-thumb\" src=\"' + poster.thumb + '\" alt=\"\" loading=\"lazy\">'\n        : '';\n      card.innerHTML =\n        thumbHtml +\n        '<div class=\"ms-pv-fallback-title\">' + poster.title + '<\/div>' +\n        '<div class=\"ms-pv-fallback-msg\">' + T.cardMsg + '<\/div>' +\n        '<a class=\"ms-pv-fallback-link\" href=\"' + poster.url + '\" target=\"_blank\" rel=\"noopener\">' +\n        '<svg viewBox=\"0 0 20 20\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\" aria-hidden=\"true\" style=\"width:18px;height:18px;\"><path d=\"M10 3v10M5 10l5 5 5-5M4 17h12\"\/><\/svg>' +\n        T.openPdf + '<\/a>';\n      this.canvasWrap.insertBefore(card, this.loadingEl);\n      this.canvas = null;\n      this.fallbackEl = card;\n    }\n\n    removeDisplayElement() {\n      if (this.canvas) {\n        this.canvas.remove();\n        this.canvas = null;\n      }\n      if (this.fallbackEl) {\n        this.fallbackEl.remove();\n        this.fallbackEl = null;\n      }\n    }\n\n    goToJpeg(index, { emit = true } = {}) {\n      const n = this.posters.length;\n      index = ((index % n) + n) % n;\n\n      this.currentIndex = index;\n      const poster = this.posters[index];\n      this.titleEl.textContent = poster.title;\n      this.updateDownloadLink();\n      this.highlightThumb(index);\n      this.showMobileCard(poster);\n\n      if (emit && this.config.deepLink) {\n        document.dispatchEvent(new CustomEvent('remus:poster-change', {\n          detail: { index }\n        }));\n      }\n    }\n\n    \/\/ No-op on mobile \u2014 there's nothing to re-fit since we don't\n    \/\/ render an inline image. Kept as a method so refit() can call\n    \/\/ it uniformly in both modes.\n    recomputeImageFit() { \/* intentionally empty *\/ }\n\n    \/\/ \u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\n    \/\/ Shared navigation + pan\/zoom machinery\n    \/\/ \u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\n    async goTo(index, opts) {\n      if (this.mode === 'jpeg') return this.goToJpeg(index, opts);\n      return this.goToPdf(index, opts);\n    }\n\n    applyTransform() {\n      if (!this.canvas) return; \/\/ fallback visible, nothing to transform\n      const zoom = this.userZoom;\n      const displayW = this.canvasCssW * zoom;\n      const displayH = this.canvasCssH * zoom;\n\n      const wrapW = this.canvasWrap.clientWidth  || 1;\n      const wrapH = this.canvasWrap.clientHeight || 1;\n\n      const minTx = (displayW <= wrapW) ? (wrapW - displayW) \/ 2 : wrapW - displayW;\n      const maxTx = (displayW <= wrapW) ? (wrapW - displayW) \/ 2 : 0;\n      const minTy = (displayH <= wrapH) ? (wrapH - displayH) \/ 2 : wrapH - displayH;\n      const maxTy = (displayH <= wrapH) ? (wrapH - displayH) \/ 2 : 0;\n\n      this.tx = clamp(this.tx, minTx, maxTx);\n      this.ty = clamp(this.ty, minTy, maxTy);\n\n      this.canvas.style.transform =\n        `translate(${Math.round(this.tx)}px, ${Math.round(this.ty)}px) scale(${zoom})`;\n\n      this.updateFitState();\n    }\n\n    updateFitState() {\n      const atFit = this.userZoom <= 1.001;\n      this.canvasWrap.dataset.fit = atFit ? 'true' : 'false';\n      this.zoomOutBtn?.setAttribute('aria-disabled', atFit ? 'true' : 'false');\n      this.resetBtn?.setAttribute('aria-disabled', atFit ? 'true' : 'false');\n      this.zoomInBtn?.setAttribute('aria-disabled',\n        this.userZoom >= ZOOM_MAX - 0.01 ? 'true' : 'false');\n    }\n\n    resetView() {\n      this.userZoom = 1;\n      const wrapW = this.canvasWrap.clientWidth  || 1;\n      const wrapH = this.canvasWrap.clientHeight || 1;\n      this.tx = (wrapW - this.canvasCssW) \/ 2;\n      this.ty = (wrapH - this.canvasCssH) \/ 2;\n      this.applyTransform();\n    }\n\n    zoomAtCenter(factor) {\n      const wrapW = this.canvasWrap.clientWidth;\n      const wrapH = this.canvasWrap.clientHeight;\n      this.zoomAt(factor, wrapW \/ 2, wrapH \/ 2);\n    }\n\n    zoomAt(factor, cxLocal, cyLocal) {\n      const newZoom = clamp(this.userZoom * factor, 1, ZOOM_MAX);\n      if (Math.abs(newZoom - this.userZoom) < 1e-4) return;\n\n      const worldX = (cxLocal - this.tx) \/ this.userZoom;\n      const worldY = (cyLocal - this.ty) \/ this.userZoom;\n      this.userZoom = newZoom;\n      this.tx = cxLocal - worldX * newZoom;\n      this.ty = cyLocal - worldY * newZoom;\n\n      if (this.userZoom <= 1.001) this.resetView();\n      else this.applyTransform();\n\n      if (this.mode === 'pdf') this.scheduleRerender();\n    }\n\n    panBy(dx, dy) {\n      this.tx += dx;\n      this.ty += dy;\n      this.applyTransform();\n    }\n\n    \/\/ \u2500\u2500 Controls wiring \u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\n    wireControls() {\n      this.prevBtn?.addEventListener('click', (e) => {\n        this.goTo(this.currentIndex - 1);\n        this.userActivity();\n        e.currentTarget.blur();\n      });\n      this.nextBtn?.addEventListener('click', (e) => {\n        this.goTo(this.currentIndex + 1);\n        this.userActivity();\n        e.currentTarget.blur();\n      });\n      this.zoomInBtn?.addEventListener('click', (e) => {\n        this.zoomAtCenter(ZOOM_STEP);\n        this.userActivity();\n        e.currentTarget.blur();\n      });\n      this.zoomOutBtn?.addEventListener('click', (e) => {\n        this.zoomAtCenter(1 \/ ZOOM_STEP);\n        this.userActivity();\n        e.currentTarget.blur();\n      });\n      this.resetBtn?.addEventListener('click', (e) => {\n        this.resetView();\n        this.userActivity();\n        e.currentTarget.blur();\n      });\n      this.playBtn?.addEventListener('click', () => {\n        this.autoplay = !this.autoplay;\n        this.playBtn.setAttribute('aria-pressed', String(this.autoplay));\n        this.playBtn.textContent = this.autoplay ? '\u23f8' : '\u25b6';\n        if (this.autoplay) this.scheduleAutoAdvance();\n        else this.stopAutoAdvance();\n        this.userActivity();\n        this.playBtn.blur();\n      });\n      this.fsBtn?.addEventListener('click', (e) => {\n        this.toggleFullscreen();\n        this.userActivity();\n        e.currentTarget.blur();\n      });\n\n      const onFsChange = () => {\n        const isNative = document.fullscreenElement === this.root\n                      || document.webkitFullscreenElement === this.root;\n        this.root.classList.toggle('is-fs-active',\n          isNative || this.root.classList.contains('is-fs-fallback'));\n      };\n      document.addEventListener('fullscreenchange', onFsChange);\n      document.addEventListener('webkitfullscreenchange', onFsChange);\n\n      if (this.playBtn) {\n        this.playBtn.setAttribute('aria-pressed', String(this.autoplay));\n        this.playBtn.textContent = this.autoplay ? '\u23f8' : '\u25b6';\n      }\n    }\n\n    \/\/ \u2500\u2500 Pointer handlers (pan + pinch + double-tap) \u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\n    wirePointerHandlers() {\n      const w = this.canvasWrap;\n\n      \/\/ UI-reawaken on any pointer\/mouse activity\n      let lastActivityMs = 0;\n      const onActivity = () => {\n        const now = Date.now();\n        if (now - lastActivityMs < 250) return;\n        lastActivityMs = now;\n        this.userActivity();\n      };\n      this.root.addEventListener('mousemove',   onActivity, { passive: true });\n      this.root.addEventListener('pointermove', onActivity, { passive: true });\n      this.root.addEventListener('touchstart',  onActivity, { passive: true });\n\n      w.addEventListener('wheel', (e) => {\n        e.preventDefault();\n        const r = w.getBoundingClientRect();\n        const factor = Math.exp(-e.deltaY * 0.0015);\n        this.zoomAt(factor, e.clientX - r.left, e.clientY - r.top);\n        this.userActivity();\n      }, { passive: false });\n\n      w.addEventListener('pointerdown', (e) => {\n        this.pointers.set(e.pointerId, { x: e.clientX, y: e.clientY });\n        if (this.pointers.size === 2) {\n          this.beginPinch();\n          w.setPointerCapture?.(e.pointerId);\n          return;\n        }\n        if (this.userZoom > 1.001) {\n          this.dragRef = { x: e.clientX, y: e.clientY };\n          w.setPointerCapture?.(e.pointerId);\n          e.preventDefault();\n        }\n      });\n\n      window.addEventListener('pointermove', (e) => {\n        if (!this.pointers.has(e.pointerId)) return;\n        this.pointers.set(e.pointerId, { x: e.clientX, y: e.clientY });\n\n        if (this.pointers.size === 2) {\n          if (!this.pinchBase) this.beginPinch();\n          this.updatePinch();\n          e.preventDefault();\n          return;\n        }\n        if (this.dragRef && Date.now() >= this.postPinchUntil) {\n          const dx = e.clientX - this.dragRef.x;\n          const dy = e.clientY - this.dragRef.y;\n          this.dragRef = { x: e.clientX, y: e.clientY };\n          this.panBy(dx, dy);\n          e.preventDefault();\n        }\n      }, { passive: false });\n\n      const endPointer = (e) => {\n        if (!this.pointers.has(e.pointerId)) return;\n        this.pointers.delete(e.pointerId);\n        if (this.pointers.size < 2 && this.pinchBase) {\n          this.pinchBase = null;\n          this.postPinchUntil = Date.now() + 200;\n          this.dragRef = null;\n          if (this.mode === 'pdf') this.scheduleRerender();\n        }\n        if (this.pointers.size === 0) this.dragRef = null;\n      };\n      window.addEventListener('pointerup', endPointer);\n      window.addEventListener('pointercancel', endPointer);\n\n      \/\/ Double-click \/ double-tap = toggle zoom(2.2x) <-> fit\n      w.addEventListener('dblclick', (e) => {\n        const r = w.getBoundingClientRect();\n        this.doubleZoomAt(e.clientX - r.left, e.clientY - r.top);\n        this.userActivity();\n      });\n\n      w.addEventListener('touchend', (e) => {\n        if (e.touches.length) return;\n        \/\/ iOS pinch-end fallback: scheduleRerender covers cases where\n        \/\/ pointerup didn't fire reliably.\n        if (this.mode === 'pdf') this.scheduleRerender();\n        const t = e.changedTouches[0];\n        const r = w.getBoundingClientRect();\n        const x = t.clientX - r.left, y = t.clientY - r.top;\n        const now = performance.now();\n        const dt = now - this.lastTap.t;\n        const dx = x - this.lastTap.x, dy = y - this.lastTap.y;\n        if (dt < DOUBLE_TAP_MS && (dx * dx + dy * dy) < (DOUBLE_TAP_PX * DOUBLE_TAP_PX)) {\n          this.doubleZoomAt(x, y);\n          this.lastTap.t = 0;\n          e.preventDefault();\n        } else {\n          this.lastTap = { t: now, x, y };\n        }\n      });\n    }\n\n    doubleZoomAt(cx, cy) {\n      if (this.userZoom > 1.01) {\n        this.resetView();\n        if (this.mode === 'pdf') this.scheduleRerender();\n      } else {\n        this.zoomAt(2.2, cx, cy);\n      }\n    }\n\n    beginPinch() {\n      const pts = [...this.pointers.values()];\n      if (pts.length < 2) return;\n      const dist = Math.hypot(pts[0].x - pts[1].x, pts[0].y - pts[1].y);\n      const r = this.canvasWrap.getBoundingClientRect();\n      const cx = ((pts[0].x + pts[1].x) \/ 2) - r.left;\n      const cy = ((pts[0].y + pts[1].y) \/ 2) - r.top;\n      const worldX = (cx - this.tx) \/ this.userZoom;\n      const worldY = (cy - this.ty) \/ this.userZoom;\n      this.pinchBase = { dist0: dist || 1, zoom0: this.userZoom, worldX, worldY };\n    }\n\n    updatePinch() {\n      if (!this.pinchBase) return;\n      const pts = [...this.pointers.values()];\n      if (pts.length < 2) return;\n      const dist = Math.hypot(pts[0].x - pts[1].x, pts[0].y - pts[1].y);\n      const r = this.canvasWrap.getBoundingClientRect();\n      const cx = ((pts[0].x + pts[1].x) \/ 2) - r.left;\n      const cy = ((pts[0].y + pts[1].y) \/ 2) - r.top;\n      const newZoom = clamp(this.pinchBase.zoom0 * (dist \/ this.pinchBase.dist0), 1, ZOOM_MAX);\n      this.userZoom = newZoom;\n      this.tx = cx - this.pinchBase.worldX * newZoom;\n      this.ty = cy - this.pinchBase.worldY * newZoom;\n      this.applyTransform();\n    }\n\n    \/\/ \u2500\u2500 Keyboard \u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\n    wireKeyboard() {\n      this.root.setAttribute('tabindex', '-1');\n      this.root.addEventListener('keydown', (e) => {\n        const tag = (e.target.tagName || '').toLowerCase();\n        if (tag === 'input' || tag === 'textarea' || tag === 'select') return;\n        switch (e.key) {\n          case 'ArrowLeft':  e.preventDefault(); this.goTo(this.currentIndex - 1); break;\n          case 'ArrowRight': e.preventDefault(); this.goTo(this.currentIndex + 1); break;\n          case '+': case '=': e.preventDefault(); this.zoomAtCenter(ZOOM_STEP); break;\n          case '-': case '_': e.preventDefault(); this.zoomAtCenter(1 \/ ZOOM_STEP); break;\n          case '0':           e.preventDefault(); this.resetView(); break;\n          case 'f': case 'F': e.preventDefault(); this.toggleFullscreen(); break;\n          case 'Escape':\n            if (this.root.classList.contains('is-fs-fallback')) {\n              e.preventDefault();\n              this.exitFullscreen();\n            }\n            break;\n        }\n        this.userActivity();\n      });\n    }\n\n    \/\/ \u2500\u2500 Resize 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type=\"button\" class=\"ms-pv-btn\" data-act=\"toggle-play\" aria-pressed=\"true\" aria-label=\"Pauza \/ P\u0159ehr\u00e1t\" title=\"Pauza \/ P\u0159ehr\u00e1t\">\u23f8<\/button>\n            <a href=\"#\" class=\"ms-pv-btn ms-pv-dl\" data-act=\"download\" target=\"_blank\" rel=\"noopener\" aria-label=\"St\u00e1hnout PDF\" title=\"St\u00e1hnout PDF\">\u2b07<\/a>\n        <\/div>\n\n        <div class=\"ms-pv-thumbs-wrap\">\n            <div class=\"ms-pv-thumbs\" role=\"tablist\" aria-label=\"Postery\"><\/div>\n        <\/div>\n\n        <div class=\"ms-pv-stage\">\n            <div class=\"ms-pv-canvas-wrap\" data-fit=\"true\">\n                <!-- JS swaps in <canvas> for desktop, <img> for mobile,\n                     or a fallback message div for mobile-with-no-jpeg. -->\n                <div class=\"ms-pv-loading\" aria-hidden=\"true\">\n                    <span class=\"ms-pv-spinner\"><\/span>\n                <\/div>\n            <\/div>\n            <button type=\"button\" class=\"ms-pv-nav ms-pv-prev\" aria-label=\"P\u0159edchoz\u00ed\">\u2039<\/button>\n            <button type=\"button\" class=\"ms-pv-nav ms-pv-next\" aria-label=\"Dal\u0161\u00ed\">\u203a<\/button>\n            <div class=\"ms-pv-title\" aria-live=\"polite\"><\/div>\n        <\/div>\n    <\/div>\n    <\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div id=\"e-n-tab-content-1545561063\" role=\"tabpanel\" aria-labelledby=\"e-n-tab-title-1545561063\" data-tab-index=\"3\" style=\"--n-tabs-title-order: 3;\" class=\" elementor-element elementor-element-76fef4a e-con-full e-flex e-con e-child\" data-id=\"76fef4a\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-38bfe04 e-flex e-con-boxed e-con e-child\" data-id=\"38bfe04\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-97a5a3d elementor-widget elementor-widget-html\" data-id=\"97a5a3d\" data-element_type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"html.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\n<!-- \u2554\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2557\n     \u2551  BLOCK 2 \u2014 PDF PRESENTATION VIEWER                             \u2551\n     \u2551  Place in: Elementor Tab 4 (\"Nejnov\u011bj\u0161\u00ed prezentace\") as HTML   \u2551\n     \u255a\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u255d -->\n\n<!-- ReMuS \u2013 Prezentace (PDF.js; no-blink paints, leaflet-safe init, width-only recalc, multi-instance, nested Tabs safe) -->\n<link rel=\"preload\" as=\"script\" href=\"https:\/\/cdn.jsdelivr.net\/npm\/pdfjs-dist@3.11.174\/build\/pdf.min.js\">\n\n<style>\n  #remus-pdf{\n    --accent:#20A2DC; --ink:#fff;\n    --glass:rgba(2,18,34,.55); --glass-border:rgba(255,255,255,.18);\n    --page-bg:#0e0f12; --shadow:0 12px 28px rgba(0,0,0,.35);\n    --toolbar-top:104px;\n    position:relative; font:500 14px\/1.45 system-ui,-apple-system,Segoe UI,Roboto,Helvetica,Arial,sans-serif; color:var(--ink)\n  }\n  #remus-pdf .frame{position:relative}\n  #remus-pdf .sticky-sentinel{height:1px}\n\n  #remus-pdf .toolbar{\n    position:sticky; top:0; z-index:20; margin-inline:auto; max-width:min(980px,100%);\n    display:flex; align-items:center; gap:8px; flex-wrap:wrap;\n    backdrop-filter:saturate(130%) blur(10px); -webkit-backdrop-filter:saturate(130%) blur(10px);\n    background:var(--glass); border:1px solid var(--glass-border); border-radius:14px; padding:10px 12px; box-shadow:var(--shadow)\n  }\n  #remus-pdf .toolbar.stuck{top:var(--toolbar-top)}\n\n  #remus-pdf .toolbar .btn, #remus-pdf .toolbar .link{\n    appearance:none; border:1px solid rgba(255,255,255,.22); background:rgba(255,255,255,.12); color:#fff;\n    border-radius:10px; padding:8px 12px; font:700 13px\/1 system-ui,-apple-system,Segoe UI,Roboto,Helvetica,Arial,sans-serif;\n    cursor:pointer; text-decoration:none; transition:background .2s ease, transform .04s ease; user-select:none\n  }\n  #remus-pdf .toolbar .btn:disabled{opacity:.45; cursor:not-allowed}\n  #remus-pdf .toolbar .btn:hover:not(:disabled), #remus-pdf .toolbar .link:hover{background:rgba(255,255,255,.2)}\n  #remus-pdf .toolbar .btn:active:not(:disabled){transform:translateY(1px)}\n  #remus-pdf .toolbar .meta{margin-left:auto; display:inline-flex; align-items:center; gap:8px; font-weight:600; opacity:.95}\n  #remus-pdf .toolbar .dot{display:inline-block; width:8px; height:8px; border-radius:50%; background:var(--accent); box-shadow:0 0 0 3px rgba(32,162,220,.25)}\n\n  #remus-pdf .pages{margin:10px auto 24px auto; max-width:min(980px,100%); display:flex; flex-direction:column; gap:14px}\n\n  #remus-pdf .page{position:relative; background:var(--page-bg); border-radius:12px; overflow:hidden; min-height:220px; box-shadow:0 14px 24px rgba(0,0,0,.22)}\n  #remus-pdf .page canvas{display:block; width:100%; height:auto; background:#111; opacity:0; transition:opacity .12s ease-out}\n  #remus-pdf .page.ready canvas{opacity:1}\n\n  #remus-pdf .page.can-pan{overflow:auto; cursor:grab; touch-action:pan-x pan-y}\n  #remus-pdf .page.can-pan:active{cursor:grabbing}\n\n  #remus-pdf .ios-tip{display:none; margin:6px auto 0; max-width:min(980px,100%); color:#d6eaff}\n\n  @media (max-width:767px){\n    #remus-pdf .toolbar{gap:6px; padding:8px 10px}\n    #remus-pdf .toolbar .btn, #remus-pdf .toolbar .link{padding:7px 10px; font-size:12px}\n  }\n<\/style>\n\n<!--\n  \u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\n  HOW TO CHANGE \/ ADD A PRESENTATION\n  \u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\n  This viewer shows ONE PDF. To swap it, update data-pdf below.\n\n  Example \u2014 new presentation for 2026:\n    data-pdf=\"\/wp-content\/uploads\/2026\/01\/ECTRIMS_2026.pdf\"\n\n  To show MULTIPLE presentations as separate viewers:\n    1. Duplicate this entire <div id=\"remus-pdf\"> block.\n    2. Change id=\"remus-pdf\" to class=\"remus-pdf\" on the copy\n       (the JS supports both id and class selectors).\n    3. Set a different data-pdf on each copy.\n\n  Deep-link URL:  \/o-registru\/#tab=4&page=3  (scrolls to page 3)\n  \u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\n-->\n<div id=\"remus-pdf\"\n     data-pdf=\"\/wp-content\/uploads\/2025\/09\/ECTRIMS_2025.pdf\"\n     data-max-dpr=\"2\"\n     data-load-all=\"1\">\n  <div class=\"frame\">\n    <div class=\"sticky-sentinel\" aria-hidden=\"true\"><\/div>\n\n    <div class=\"toolbar\" role=\"group\" aria-label=\"PDF ovl\u00e1d\u00e1n\u00ed\">\n      <button class=\"btn\" data-act=\"zoom-out\" aria-label=\"Zmen\u0161it\">Zoom \u2212<\/button>\n      <button class=\"btn\" data-act=\"zoom-in\"  aria-label=\"Zv\u011bt\u0161it\">Zoom +<\/button>\n      <button class=\"btn\" data-act=\"reset\"    aria-label=\"P\u0159izp\u016fsobit \u0161\u00ed\u0159ce\">Fit<\/button>\n      <a class=\"link open\" target=\"_blank\" rel=\"noopener\">Open<\/a>\n      <a class=\"link dl\" download>Download<\/a>\n      <span class=\"meta\" aria-live=\"polite\">\n        <span class=\"dot\" aria-hidden=\"true\"><\/span>\n        <span>Page <b class=\"curr\">1<\/b>\/<span class=\"total\">?<\/span><\/span>\n      <\/span>\n    <\/div>\n\n    <div class=\"ios-tip\">Na iOS m\u016f\u017eete pou\u017e\u00edt tla\u010d\u00edtko <b>Open<\/b> pro nativn\u00ed prohl\u00ed\u017ee\u010d PDF (rychlej\u0161\u00ed a \u00fasporn\u011bj\u0161\u00ed).<\/div>\n    <div class=\"pages\" aria-label=\"Str\u00e1nky PDF\"><\/div>\n  <\/div>\n<\/div>\n\n<script>\n(() => {'use strict';\n  const $  = (sel, ctx=document) => ctx.querySelector(sel);\n  const $$ = (sel, ctx=document) => Array.from(ctx.querySelectorAll(sel));\n  const clamp = (v, a, b) => Math.max(a, Math.min(v, b));\n  const on = (el, ev, fn, opt) => el && el.addEventListener(ev, fn, opt);\n  const idle = (cb) => ('requestIdleCallback' in window) ? requestIdleCallback(cb) : setTimeout(cb, 0);\n\n  const PDF_JS     = 'https:\/\/cdn.jsdelivr.net\/npm\/pdfjs-dist@3.11.174\/build\/pdf.min.js';\n  const PDF_WORKER = 'https:\/\/cdn.jsdelivr.net\/npm\/pdfjs-dist@3.11.174\/build\/pdf.worker.min.js';\n  function loadScript(src){\n    return new Promise((res, rej)=>{\n      if (document.querySelector(`script[src=\"${src}\"]`)) return res();\n      const s=document.createElement('script'); s.src=src; s.async=true;\n      s.onload=res; s.onerror=()=>rej(new Error('Nepoda\u0159ilo se na\u010d\u00edst: '+src));\n      document.head.appendChild(s);\n    });\n  }\n  async function ensurePdfLib(){\n    await loadScript(PDF_JS);\n    const pdfjs = window['pdfjsLib'];\n    pdfjs.GlobalWorkerOptions.workerSrc = PDF_WORKER;\n    return pdfjs;\n  }\n\n  function collectAncestorTabButtons(root){\n    const btns=[]; let n=root.parentElement;\n    while(n){\n      if(n.matches('[id^=\"e-n-tab-content-\"], [id^=\"elementor-tab-content-\"], [role=\"tabpanel\"]')){\n        const id=n.id;\n        if(id){\n          const btn=document.querySelector(`.e-n-tab-title[aria-controls=\"${id}\"], .elementor-tab-title[aria-controls=\"${id}\"]`);\n          if(btn) btns.push(btn);\n        }\n      }\n      n=n.parentElement;\n    }\n    return btns;\n  }\n  const isTabActive = (btn) => btn.getAttribute('aria-selected')==='true' || btn.classList.contains('elementor-active');\n\n  async function setupViewer(root){\n    if(!root || root.dataset.remusInited==='1') return;\n    root.dataset.remusInited='1';\n\n    const pdfUrl  = (root.dataset.pdf || '').trim();\n    const maxDpr  = Number(root.dataset.maxDpr||2);\n    const LOAD_ALL= root.dataset.loadAll==='1';\n    const dpr     = Math.min(maxDpr, window.devicePixelRatio||1);\n\n    const pagesEl = $('.pages', root);\n    const currEl  = $('.curr', root);\n    const totalEl = $('.total', root);\n    const btnIn   = $('[data-act=\"zoom-in\"]', root);\n    const btnOut  = $('[data-act=\"zoom-out\"]', root);\n    const btnFit  = $('[data-act=\"reset\"]', root);\n    const iosTip  = $('.ios-tip', root);\n    const toolbar = $('.toolbar', root);\n    const sentinel= $('.sticky-sentinel', root);\n\n    const openA=$('.open', root); const dlA=$('.dl', root);\n    if(openA) openA.href = pdfUrl || '#';\n    if(dlA)   dlA.href   = pdfUrl || '#';\n    if(!pdfUrl){\n      if(openA) openA.setAttribute('aria-disabled','true');\n      if(dlA)   dlA.setAttribute('aria-disabled','true');\n      console.warn('ReMuS PDF: instance p\u0159esko\u010dena \u2013 chyb\u00ed data-pdf.', root);\n      return;\n    }\n\n    let pdfDoc=null, uiScale=1, rasterScale=1, minScale=1, maxScale=4;\n    let io=null, initialized=false;\n    const meta=new Map();\n    const renderTasks=new Map();\n    let lastWidth = null;\n\n    const viewportMidY = () => window.innerHeight \/ 2;\n    function getBestCenteredPageIndex(){\n      const midY = viewportMidY();\n      let bestI=1, bestDist=Infinity;\n      $$('.page', pagesEl).forEach(el=>{\n        const r=el.getBoundingClientRect();\n        const d=Math.abs((r.top+r.height\/2)-midY);\n        if(d<bestDist){bestDist=d; bestI=Number(el.dataset.p||'1');}\n      });\n      return bestI;\n    }\n    function updateCounterFromViewport(){\n      const i=getBestCenteredPageIndex();\n      if(currEl && currEl.textContent!==String(i)) currEl.textContent=String(i);\n      return i;\n    }\n\n    async function ensurePdf(){\n      const pdfjs=await ensurePdfLib();\n      pdfDoc=await pdfjs.getDocument({url:pdfUrl}).promise;\n      totalEl.textContent=String(pdfDoc.numPages);\n      return pdfDoc;\n    }\n    function ensurePageDom(i){\n      let holder=pagesEl.querySelector(`.page[data-p=\"${i}\"]`);\n      if(!holder){\n        holder=document.createElement('div'); holder.className='page'; holder.dataset.p=String(i);\n        holder.appendChild(document.createElement('canvas'));\n        pagesEl.appendChild(holder);\n        if(io) io.observe(holder);\n      }\n      return holder;\n    }\n    async function primePageMeta(i){\n      if(meta.has(i)) return meta.get(i);\n      const page=await pdfDoc.getPage(i);\n      const rotation=page.rotate||0;\n      const vp=page.getViewport({scale:1, rotation});\n      const info={w1:vp.width, h1:vp.height, rot:rotation};\n      meta.set(i, info);\n      return info;\n    }\n    function containerWidth(){\n      return Math.max(0, pagesEl.getBoundingClientRect().width || root.getBoundingClientRect().width || 0);\n    }\n    function computeMinScaleForWidth(w1){\n      const avail=Math.max(320, containerWidth() || 800);\n      return clamp(avail \/ w1, 0.5, 3.0);\n    }\n    function updateZoomButtons(){\n      const bestI=getBestCenteredPageIndex();\n      const m=meta.get(bestI);\n      if(!m) return;\n      minScale=computeMinScaleForWidth(m.w1);\n      maxScale=Math.max(minScale*4, minScale+.5);\n      if(btnOut) btnOut.disabled = uiScale <= (minScale+1e-3);\n    }\n\n    async function renderPage(i, opts={force:false, preview:false}){\n      if(!pdfDoc) return;\n      const m=await primePageMeta(i);\n      const pageEl=ensurePageDom(i);\n      const canvas=pageEl.querySelector('canvas');\n      canvas.style.width  = Math.round(m.w1*uiScale)+'px';\n      canvas.style.height = Math.round(m.h1*uiScale)+'px';\n      const relDelta=Math.abs(uiScale\/rasterScale-1);\n      const needRepaint=opts.force || (relDelta>0.25) || (canvas.width===0 || canvas.height===0);\n      if(!needRepaint && !opts.preview) return;\n      const prev=renderTasks.get(i);\n      if(prev && prev.cancel){ try{prev.cancel();}catch(_){} }\n      const effectiveDpr = opts.preview ? 1 : dpr;\n      const targetScale  = opts.preview ? Math.max(minScale, Math.min(uiScale, minScale*1.05)) : uiScale;\n      const page=await pdfDoc.getPage(i);\n      const vp=page.getViewport({scale:targetScale*effectiveDpr, rotation:m.rot});\n      const w=Math.floor(vp.width), h=Math.floor(vp.height);\n      let off, octx;\n      if('OffscreenCanvas' in window){ off=new OffscreenCanvas(w,h); octx=off.getContext('2d',{alpha:false}); }\n      else { off=document.createElement('canvas'); off.width=w; off.height=h; octx=off.getContext('2d',{alpha:false}); }\n      if(octx){octx.save(); octx.fillStyle='#111'; octx.fillRect(0,0,w,h); octx.restore();}\n      let task;\n      try{\n        task=page.render({canvasContext:octx, viewport:vp, intent:'display'});\n        renderTasks.set(i, task);\n        await task.promise;\n        if(canvas.width!==w || canvas.height!==h){ canvas.width=w; canvas.height=h; }\n        const vctx=canvas.getContext('2d', {alpha:false});\n        try{ vctx.drawImage(off,0,0); } catch(_){ if(off.transferToImageBitmap){ vctx.drawImage(off.transferToImageBitmap(),0,0); } }\n        if(!opts.preview) rasterScale=targetScale;\n        if(!pageEl.classList.contains('ready')) pageEl.classList.add('ready');\n      }catch(err){\n        if(!err || err.name!=='RenderingCancelledException'){\n          if(!opts.preview) await renderPage(i, {force:true, preview:true});\n        }\n      }finally{\n        if(renderTasks.get(i)===task) renderTasks.delete(i);\n      }\n    }\n\n    function rerenderVisible(opts={force:false}){\n      const vTop=0, vBottom=window.innerHeight;\n      $$('.page', pagesEl).forEach(el=>{\n        const r=el.getBoundingClientRect();\n        const near=(r.bottom>vTop-1200)&&(r.top<vBottom+1200);\n        if(near) renderPage(Number(el.dataset.p), {force:opts.force, preview:false});\n      });\n      updateZoomButtons();\n      togglePanningClass();\n    }\n\n    function cleanupFar(iCenter){\n      if(LOAD_ALL) return;\n      const keepFrom=Math.max(1, iCenter-4);\n      const keepTo=Math.min(pdfDoc.numPages, iCenter+4);\n      $$('.page', pagesEl).forEach(p=>{\n        const i=Number(p.dataset.p);\n        if(i<keepFrom || i>keepTo){\n          const c=p.querySelector('canvas');\n          if(c){ c.width=0; c.height=0; c.style.width=''; c.style.height=''; }\n        }\n      });\n    }\n\n    function setupIO(){\n      if(io) io.disconnect();\n      io=new IntersectionObserver((entries)=>{\n        entries.forEach(e=>{\n          if(!e.isIntersecting) return;\n          const i=Number(e.target.dataset.p);\n          renderPage(i,{force:false, preview:false}).then(()=>{\n            currEl.textContent=String(updateCounterFromViewport());\n            cleanupFar(i);\n          });\n        });\n      }, {root:null, rootMargin:'1400px 0px', threshold:0.01});\n      new MutationObserver(muts=>{\n        muts.forEach(m=>m.addedNodes.forEach(n=>{\n          if(n.nodeType===1 && n.classList.contains('page')) io.observe(n);\n        }));\n      }).observe(pagesEl, {childList:true});\n    }\n\n    function togglePanningClass(){\n      const i=getBestCenteredPageIndex();\n      const m=meta.get(i); if(!m) return;\n      const currMin=computeMinScaleForWidth(m.w1);\n      const zoomed=uiScale>(currMin+1e-3);\n      $$('.page', pagesEl).forEach(el=>el.classList.toggle('can-pan', zoomed));\n    }\n    let repaintTimer=null;\n    function scheduleCrispRepaint(){ clearTimeout(repaintTimer); repaintTimer=setTimeout(()=>rerenderVisible({force:true}), 280); }\n    function zoomBy(f){\n      uiScale=clamp(uiScale*f, 0.25, 12);\n      updateZoomButtons();\n      uiScale=clamp(uiScale, minScale, maxScale);\n      rerenderVisible({force:false}); scheduleCrispRepaint();\n    }\n    function fitToWidth(){\n      updateZoomButtons(); uiScale=minScale;\n      rerenderVisible({force:false}); rerenderVisible({force:true});\n    }\n    on(btnIn,'click',()=>zoomBy(1.2));\n    on(btnOut,'click',()=>zoomBy(1\/1.2));\n    on(btnFit,'click',fitToWidth);\n\n    const headerOffset = parseInt(getComputedStyle(root).getPropertyValue('--toolbar-top'))||84;\n    const stuckObserver=new IntersectionObserver((entries)=>{\n      const entry=entries[0];\n      if(entry && entry.isIntersecting) toolbar.classList.remove('stuck');\n      else toolbar.classList.add('stuck');\n    }, {root:null, threshold:0, rootMargin:`-${headerOffset}px 0px 0px 0px`});\n    stuckObserver.observe(sentinel);\n\n    const ancestorBtns=collectAncestorTabButtons(root);\n    const allTabsActive = ()=>ancestorBtns.every(isTabActive);\n    const isVisible = ()=>{ const r=root.getBoundingClientRect(); return r.width>0 && r.height>0 && !!root.offsetParent; };\n    const maybeStart=()=>{ if(!initialized && allTabsActive() && isVisible()) init(); };\n    ancestorBtns.forEach(btn=>{\n      new MutationObserver(maybeStart).observe(btn, {attributes:true, attributeFilter:['aria-selected','class']});\n      btn.addEventListener('click', ()=>setTimeout(maybeStart,0), {passive:true});\n    });\n    const ioVisible=new IntersectionObserver(()=>maybeStart(), {threshold:0.01}); ioVisible.observe(root);\n    const roGate=new ResizeObserver(()=>maybeStart()); roGate.observe(root);\n\n    async function estimateBaseWidth(){\n      const sampleW=[]; const maxCheck=Math.min(8, pdfDoc.numPages);\n      for(let i=1;i<=maxCheck;i++){ const m=await primePageMeta(i); sampleW.push(m.w1); }\n      return Math.max(...sampleW);\n    }\n\n    async function init(){\n      if(initialized) return; initialized=true;\n      try{\n        await ensurePdf();\n        const frag=document.createDocumentFragment();\n        for(let i=1;i<=pdfDoc.numPages;i++){\n          const p=document.createElement('div'); 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V\u00fdsledky registru ReMuS jsou d\u00e1le prezentov\u00e1ny na odborn\u00fdch tuzemsk\u00fdch [&hellip;] <\/p>\n","protected":false},"author":1,"featured_media":3237,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"inline_featured_image":false,"footnotes":""},"class_list":["post-38","page","type-page","status-publish","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/www.multiplesclerosis.cz\/en\/wp-json\/wp\/v2\/pages\/38","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.multiplesclerosis.cz\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.multiplesclerosis.cz\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.multiplesclerosis.cz\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.multiplesclerosis.cz\/en\/wp-json\/wp\/v2\/comments?post=38"}],"version-history":[{"count":18,"href":"https:\/\/www.multiplesclerosis.cz\/en\/wp-json\/wp\/v2\/pages\/38\/revisions"}],"predecessor-version":[{"id":9392,"href":"https:\/\/www.multiplesclerosis.cz\/en\/wp-json\/wp\/v2\/pages\/38\/revisions\/9392"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.multiplesclerosis.cz\/en\/wp-json\/wp\/v2\/media\/3237"}],"wp:attachment":[{"href":"https:\/\/www.multiplesclerosis.cz\/en\/wp-json\/wp\/v2\/media?parent=38"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}