Real-world effectiveness of cladribine as an escalation strategy for MS: Insights from the Czech nationwide ReMuS registry
A new study published in the Journal of Central Nervous System Disease provides insights into the efficacy of cladribine in the treatment of multiple sclerosis (MS) in real-world clinical practice. The paper uses data from the Czech nationwide ReMuS registry and...
Big Multiple Sclerosis Data network: an international registry research network
Article doc. Anna Glaser from Karolinska Institutet, Sweden, focuses on the importance and contribution of European multiple sclerosis registries, specifically the Big Multiple Sclerosis Data Network (BMSD) project, in which ReMuS is actively involved...
The impact of healthcare systems on the clinical diagnosis and disease-modifying treatment usage in relapse-onset multiple sclerosis: a real-world perspective in five registries across Europe
In their new study, a team led by Richard Nicholas looked at how health systems in different countries influence clinical diagnosis and access to treatment for multiple sclerosis...
Is breastfeeding in MS harmful or not? An answer from real-world Czech data
The original article by Pavel Hradílek, M.D., Ph.D. from the University Hospital Ostrava based on the ReMuS registry data was published in the journal Multiple Sclerosis and Related Disorders. Because the influence of breastfeeding and its duration on the course of multiple sclerosis is unclear, the authors analyzed real data on breastfeeding women with MS and the course of their disease...
Does initial high efficacy therapy in multiple sclerosis surpass escalation treatment strategy? A comparison of patients with relapsing-remitting multiple sclerosis in the Czech and Swedish national multiple sclerosis registries.
Expert article by Ing. Tereza Hrnčiarová, Ph.D. from the 1st Medical Faculty of Charles University deals with the issue of treatment strategies in relapsing-remitting multiple sclerosis. Her work is based on data from the Czech ReMuS registry and the Swedish SMSR (Swedish MS Registry). It builds on the...
The Czech National MS Registry (ReMuS): Data trends in multiple sclerosis patients whose first disease-modifying therapies were initiated from 2013 to 2021
Multiple sclerosis is a serious neuroimmunological disease and data on its incidence and treatment are systematically and longitudinally evaluated by the national ReMuS registry. Trends in the treatment of patients in the Czech Republic were discussed by Dominika Št'astná, M.D., Ph.D. from the General University Hospital in Prague in her...
Proportion and characteristics of secondary progressive multiple sclerosis in five European registries using objective classifiers
Secondary progressive multiple sclerosis (SPRS) represents an important stage in the development of multiple sclerosis, but is often difficult to diagnose accurately. A study conducted in five European countries used objective classifiers to determine the proportion and characteristics of SPRS in different registries of multiple sclerosis patients, including the national ReMuS registry. The findings suggest ...
To be or not to be vaccinated: The risk of MS or NMOSD relapse after COVID-19 vaccination and infection
In a recent study published in Multiple Sclerosis and Related Disorders, researchers examined the risk of relapse in patients with multiple sclerosis (MS) and neuromyelitis optica (NMOSD) after vaccination against COVID-19 and after undergoing COVID-19. The study looked at data from the Czech national ReMuS registry and showed...
Analysis of the Group of Pediatric Patients With Relapsing-Remitting Multiple Sclerosis: Data From the Czech National Registry
Multiple sclerosis can also affect children, although it is a rarer form of the disease. Approximately 3-10 % patients will develop multiple sclerosis before the age of 16. This study focuses on the analysis of a group of pediatric patients with relapsing form of multiple sclerosis who started treatment...
Is pregnancy in MS patients safe and what is its impact on MS course? Real World evidence of 1,533 pregnancies in Czech Republic
Pregnancy in patients with multiple sclerosis (MS) requires special care, particularly with regard to decisions regarding disease-modifying disease (DMD) treatment and counselling regarding the period of conception, pregnancy and the postpartum period. This study aims to analyze the impact of pregnancy, childbirth or miscarriage on the course of multiple sclerosis ...