Article Prof. Dana Horáková published in the journal Multiple Sclerosis News offers a detailed look at the creation and development of the Czech national registry of multiple sclerosis patients, ReMuS, since its inception in 2013. The reader will find information about the structure of the registry, the data collection process, and how the registry has gradually expanded to include more than eight thousand patients across 14 specialized centers in the Czech Republic. The article also provides an overview of key outputs from the registry, including demographic data, disease progression, treatment types and patient employment status. In addition, it discusses the importance of long-term follow-up of patients and presents plans for future expansion of the registry and improvement of the quality of data collected.